Although hyperspectral images provide abundant information about objects, their high
dimensionality also substantially increases computational burden. Dimensionality reduction offers …

Background and Aim The clinical features and etiology of B udd– C hiari syndrome ( BCS )
vary from region to region, and there is lack of large sample studies about BCS in C hina. The …

Network pharmacology is a novel approach that uses bioinformatics to predict and identify
multiple drug targets and interactions in disease. Here, we used network pharmacology to …

Network pharmacology uses bioinformatics to broaden our understanding of drug actions
and thereby to advance drug discovery. Here we apply network pharmacology to generate …

In this study, we designed and synthesized a series of deoxyvasicinone–donepezil hybrids
and determined whether they could be used as novel multitarget inhibitors for Alzheimer’s …

In this research, extraction optimization, preliminary characterization and immunological
activities in vitro of polysaccharides from Elaeagnus angustifolia L. pulp were investigated. A …

A response surface and Box-Behnken design approach was applied to augment polysaccharide
extraction from the residue of Rhizoma gastrodiae. Statistical analysis revealed that the …

A series of novel bivalent β-carbolines were synthesized and evaluated for their anti-proliferative
activities on a panel of cancer cell lines, apoptosis induction and cell cycle effects. The …

In this study, a series of potential ligands for the treatment of AD were synthesised and
characterised as novel harmine derivatives modified at position 9 with benzyl piperazinyl. In vitro …

A series of multitarget ligands was designed by introducing several structurally diverse
aminoacetamide groups at position 6 of the deoxyvasicinone group, with the aim of obtaining …