Rawat R - Search Results

1

The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance.

Rawat R, Whitty A, Tonge PJ. Rawat R, et al. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13881-6. doi: 10.1073/pnas.2235848100. Epub 2003 Nov 17. Proc Natl Acad Sci U S A. 2003. PMID: 14623976 Free PMC article.

2

Evidence from Raman spectroscopy that InhA, the mycobacterial enoyl reductase, modulates the conformation of the NADH cofactor to promote catalysis.

Bell AF, Stratton CF, Zhang X, Novichenok P, Jaye AA, Nair PA, Parikh S, Rawat R, Tonge PJ. Bell AF, et al. Among authors: rawat r. J Am Chem Soc. 2007 May 23;129(20):6425-31. doi: 10.1021/ja068219m. Epub 2007 May 2. J Am Chem Soc. 2007. PMID: 17472376

3

Probing mechanisms of resistance to the tuberculosis drug isoniazid: Conformational changes caused by inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis.

Kruh NA, Rawat R, Ruzsicska BP, Tonge PJ. Kruh NA, et al. Among authors: rawat r. Protein Sci. 2007 Aug;16(8):1617-27. doi: 10.1110/ps.062749007. Epub 2007 Jun 28. Protein Sci. 2007. PMID: 17600151 Free PMC article.

4

Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli.

Rafi S, Novichenok P, Kolappan S, Stratton CF, Rawat R, Kisker C, Simmerling C, Tonge PJ. Rafi S, et al. Among authors: rawat r. J Biol Chem. 2006 Dec 22;281(51):39285-39293. doi: 10.1074/jbc.M608758200. Epub 2006 Sep 29. J Biol Chem. 2006. PMID: 17012233 Free PMC article.

5

Structure- and substrate-based inhibitor design for Clostridium botulinum neurotoxin serotype A.

Kumaran D, Rawat R, Ludivico ML, Ahmed SA, Swaminathan S. Kumaran D, et al. Among authors: rawat r. J Biol Chem. 2008 Jul 4;283(27):18883-91. doi: 10.1074/jbc.M801240200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18434312 Free article.

6

Conjugated fatty acid synthesis: residues 111 and 115 influence product partitioning of Momordica charantia conjugase.

Rawat R, Yu XH, Sweet M, Shanklin J. Rawat R, et al. J Biol Chem. 2012 May 11;287(20):16230-7. doi: 10.1074/jbc.M111.325316. Epub 2012 Mar 26. J Biol Chem. 2012. PMID: 22451660 Free PMC article.

7

Characterization and analysis of the cotton cyclopropane fatty acid synthase family and their contribution to cyclopropane fatty acid synthesis.

Yu XH, Rawat R, Shanklin J. Yu XH, et al. Among authors: rawat r. BMC Plant Biol. 2011 May 25;11:97. doi: 10.1186/1471-2229-11-97. BMC Plant Biol. 2011. PMID: 21612656 Free PMC article.

8

Substrate binding mode and its implication on drug design for botulinum neurotoxin A.

Kumaran D, Rawat R, Ahmed SA, Swaminathan S. Kumaran D, et al. Among authors: rawat r. PLoS Pathog. 2008 Sep 26;4(9):e1000165. doi: 10.1371/journal.ppat.1000165. PLoS Pathog. 2008. PMID: 18818739 Free PMC article.

9

High level expression of the light chain of botulinum neurotoxin serotype C1 and an efficient HPLC assay to monitor its proteolytic activity.

Rawat R, Ashraf Ahmed S, Swaminathan S. Rawat R, et al. Protein Expr Purif. 2008 Aug;60(2):165-9. doi: 10.1016/j.pep.2008.03.010. Epub 2008 Mar 25. Protein Expr Purif. 2008. PMID: 18482846

10

The Clinical Profile of Heatstroke Patients Admitted to the Intensive Care Unit: A Case Series From a Tertiary Care Center in New Delhi, India.

Aggarwal A, Rawat R, Sharma B, Saini K, Damera A, Yadav L, Das SK. Aggarwal A, et al. Among authors: rawat r. Cureus. 2024 Oct 22;16(10):e72114. doi: 10.7759/cureus.72114. eCollection 2024 Oct. Cureus. 2024. PMID: 39575050 Free PMC article.

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