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Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism.
Ouimet M, Koster S, Sakowski E, Ramkhelawon B, van Solingen C, Oldebeken S, Karunakaran D, Portal-Celhay C, Sheedy FJ, Ray TD, Cecchini K, Zamore PD, Rayner KJ, Marcel YL, Philips JA, Moore KJ. Ouimet M, et al. Among authors: philips ja. Nat Immunol. 2016 Jun;17(6):677-86. doi: 10.1038/ni.3434. Epub 2016 Apr 18. Nat Immunol. 2016. PMID: 27089382 Free PMC article.
Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis.
Sakowski ET, Koster S, Portal Celhay C, Park HS, Shrestha E, Hetzenecker SE, Maurer K, Cadwell K, Philips JA. Sakowski ET, et al. Among authors: philips ja. PLoS Pathog. 2015 Jul 30;11(7):e1005076. doi: 10.1371/journal.ppat.1005076. eCollection 2015 Jul. PLoS Pathog. 2015. PMID: 26225865 Free PMC article.
Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4+ T-cell activation.
Portal-Celhay C, Tufariello JM, Srivastava S, Zahra A, Klevorn T, Grace PS, Mehra A, Park HS, Ernst JD, Jacobs WR Jr, Philips JA. Portal-Celhay C, et al. Among authors: philips ja. Nat Microbiol. 2016 Dec 5;2:16232. doi: 10.1038/nmicrobiol.2016.232. Nat Microbiol. 2016. PMID: 27918526 Free PMC article.
Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.
Köster S, Upadhyay S, Chandra P, Papavinasasundaram K, Yang G, Hassan A, Grigsby SJ, Mittal E, Park HS, Jones V, Hsu FF, Jackson M, Sassetti CM, Philips JA. Köster S, et al. Among authors: philips ja. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8711-E8720. doi: 10.1073/pnas.1707792114. Epub 2017 Sep 27. Proc Natl Acad Sci U S A. 2017. PMID: 28973896 Free PMC article.
Why macrophages cannot LAP up TB.
Köster S, Upadhyay S, Philips JA. Köster S, et al. Among authors: philips ja. Autophagy. 2018;14(3):552-554. doi: 10.1080/15548627.2018.1425054. Epub 2018 Feb 21. Autophagy. 2018. PMID: 29313424 Free PMC article.
Tuberculosis and the art of macrophage manipulation.
Upadhyay S, Mittal E, Philips JA. Upadhyay S, et al. Among authors: philips ja. Pathog Dis. 2018 Jun 1;76(4):fty037. doi: 10.1093/femspd/fty037. Pathog Dis. 2018. PMID: 29762680 Free PMC article. Review.
66 results