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Page 1
A Membrane-Bound Diacylglycerol Species Induces PKCϵ-Mediated Hepatic Insulin Resistance.
Lyu K, Zhang Y, Zhang D, Kahn M, Ter Horst KW, Rodrigues MRS, Gaspar RC, Hirabara SM, Luukkonen PK, Lee S, Bhanot S, Rinehart J, Blume N, Rasch MG, Serlie MJ, Bogan JS, Cline GW, Samuel VT, Shulman GI. Lyu K, et al. Cell Metab. 2020 Oct 6;32(4):654-664.e5. doi: 10.1016/j.cmet.2020.08.001. Epub 2020 Sep 2. Cell Metab. 2020. PMID: 32882164 Free PMC article.
Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease.
Luukkonen PK, Dufour S, Lyu K, Zhang XM, Hakkarainen A, Lehtimäki TE, Cline GW, Petersen KF, Shulman GI, Yki-Järvinen H. Luukkonen PK, et al. Among authors: lyu k. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7347-7354. doi: 10.1073/pnas.1922344117. Epub 2020 Mar 16. Proc Natl Acad Sci U S A. 2020. PMID: 32179679 Free PMC article.
Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice.
Abulizi A, Vatner DF, Ye Z, Wang Y, Camporez JP, Zhang D, Kahn M, Lyu K, Sirwi A, Cline GW, Hussain MM, Aspichueta P, Samuel VT, Shulman GI. Abulizi A, et al. Among authors: lyu k. J Lipid Res. 2020 Dec;61(12):1565-1576. doi: 10.1194/jlr.RA119000586. Epub 2020 Sep 9. J Lipid Res. 2020. PMID: 32907986 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33455703
[No title available]
[No authors listed] [No authors listed] PMID: 33531237
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.
Gaspar RC, Lyu K, Hubbard BT, Leitner BP, Luukkonen PK, Hirabara SM, Sakuma I, Nasiri A, Zhang D, Kahn M, Cline GW, Pauli JR, Perry RJ, Petersen KF, Shulman GI. Gaspar RC, et al. Among authors: lyu k. Diabetologia. 2023 Mar;66(3):567-578. doi: 10.1007/s00125-022-05838-8. Epub 2022 Dec 1. Diabetologia. 2023. PMID: 36456864 Free PMC article.
202 results