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The TSC-mTOR pathway regulates macrophage polarization.
Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. Byles V, et al. Among authors: horng t. Nat Commun. 2013;4:2834. doi: 10.1038/ncomms3834. Nat Commun. 2013. PMID: 24280772 Free PMC article.
ROS sets the stage for macrophage differentiation.
Covarrubias A, Byles V, Horng T. Covarrubias A, et al. Among authors: horng t. Cell Res. 2013 Aug;23(8):984-5. doi: 10.1038/cr.2013.88. Epub 2013 Jul 9. Cell Res. 2013. PMID: 23835480 Free PMC article.
IL-6 strikes a balance in metabolic inflammation.
Covarrubias AJ, Horng T. Covarrubias AJ, et al. Among authors: horng t. Cell Metab. 2014 Jun 3;19(6):898-9. doi: 10.1016/j.cmet.2014.05.009. Cell Metab. 2014. PMID: 24896536 Free PMC article.
mTOR trains heightened macrophage responses.
Horng T. Horng T. Trends Immunol. 2015 Jan;36(1):1-2. doi: 10.1016/j.it.2014.11.004. Epub 2014 Dec 2. Trends Immunol. 2015. PMID: 25488670 Free PMC article.
Metabolism as a guiding force for immunity.
Jung J, Zeng H, Horng T. Jung J, et al. Among authors: horng t. Nat Cell Biol. 2019 Jan;21(1):85-93. doi: 10.1038/s41556-018-0217-x. Epub 2019 Jan 2. Nat Cell Biol. 2019. PMID: 30602764 Review.
Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses.
Langston PK, Nambu A, Jung J, Shibata M, Aksoylar HI, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani ET, Locasale JW, Snyder NW, Horng T. Langston PK, et al. Among authors: horng t. Nat Immunol. 2019 Sep;20(9):1186-1195. doi: 10.1038/s41590-019-0453-7. Epub 2019 Aug 5. Nat Immunol. 2019. PMID: 31384058 Free PMC article.
71 results