Barford D - Search Results

1

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.

Komander D, Patel M, Laurin M, Fradet N, Pelletier A, Barford D, Côté JF. Komander D, et al. Among authors: barford d. Mol Biol Cell. 2008 Nov;19(11):4837-51. doi: 10.1091/mbc.e08-04-0345. Epub 2008 Sep 3. Mol Biol Cell. 2008. PMID: 18768751 Free PMC article.

2

The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs.

Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D. Groves MR, et al. Among authors: barford d. Cell. 1999 Jan 8;96(1):99-110. doi: 10.1016/s0092-8674(00)80963-0. Cell. 1999. PMID: 9989501 Free article.

3

The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis.

Song H, Mugnier P, Das AK, Webb HM, Evans DR, Tuite MF, Hemmings BA, Barford D. Song H, et al. Among authors: barford d. Cell. 2000 Feb 4;100(3):311-21. doi: 10.1016/s0092-8674(00)80667-4. Cell. 2000. PMID: 10676813 Free article.

4

Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B.

Salmeen A, Andersen JN, Myers MP, Tonks NK, Barford D. Salmeen A, et al. Among authors: barford d. Mol Cell. 2000 Dec;6(6):1401-12. doi: 10.1016/s1097-2765(00)00137-4. Mol Cell. 2000. PMID: 11163213 Free article.

5

Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.

Song H, Hanlon N, Brown NR, Noble ME, Johnson LN, Barford D. Song H, et al. Among authors: barford d. Mol Cell. 2001 Mar;7(3):615-26. doi: 10.1016/s1097-2765(01)00208-8. Mol Cell. 2001. PMID: 11463386 Free article.

6

Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit.

Au SW, Leng X, Harper JW, Barford D. Au SW, et al. Among authors: barford d. J Mol Biol. 2002 Mar 1;316(4):955-68. doi: 10.1006/jmbi.2002.5399. J Mol Biol. 2002. PMID: 11884135

7

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.

Yang J, Cron P, Thompson V, Good VM, Hess D, Hemmings BA, Barford D. Yang J, et al. Among authors: barford d. Mol Cell. 2002 Jun;9(6):1227-40. doi: 10.1016/s1097-2765(02)00550-6. Mol Cell. 2002. PMID: 12086620 Free article.

8

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP.

Yang J, Cron P, Good VM, Thompson V, Hemmings BA, Barford D. Yang J, et al. Among authors: barford d. Nat Struct Biol. 2002 Dec;9(12):940-4. doi: 10.1038/nsb870. Nat Struct Biol. 2002. PMID: 12434148

9

Regulation of protein kinases in insulin, growth factor and Wnt signalling.

Pearl LH, Barford D. Pearl LH, et al. Among authors: barford d. Curr Opin Struct Biol. 2002 Dec;12(6):761-7. doi: 10.1016/s0959-440x(02)00386-x. Curr Opin Struct Biol. 2002. PMID: 12504681 Review.

10

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.

Wan PT, Garnett MJ, Roe SM, Lee S, Niculescu-Duvaz D, Good VM, Jones CM, Marshall CJ, Springer CJ, Barford D, Marais R; Cancer Genome Project. Wan PT, et al. Among authors: barford d. Cell. 2004 Mar 19;116(6):855-67. doi: 10.1016/s0092-8674(04)00215-6. Cell. 2004. PMID: 15035987 Free article.

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