We got a report of permanent JS problems on IE 11 on ro.wp [1], which in theory [2] is still supported. See comment below for details on the console output. This seems to be different from the wikidata issue reported at [3] (at least I get a different error)
[1] https://ro.wikipedia.org/wiki/Wikipedia:Cafenea#Probleme_cu_interfa.C8.9Ba
[2] https://www.mediawiki.org/wiki/Compatibility#Browser_support_matrix
[3] https://www.wikidata.org/wiki/Wikidata:Contact_the_development_team#A_bug.3F