(Q39805693)

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LFA-1 antagonists as agents limiting human immunodeficiency virus type 1 infection and transmission and potentiating the effect of the fusion inhibitor T-20.

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Europe PubMed Central

PMC publication ID

14 September 2017

LFA-1 antagonists as agents limiting human immunodeficiency virus type 1 infection and transmission and potentiating the effect of the fusion inhibitor T-20. (English)

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

author name string

Mélanie R Tardif

1

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Caroline Gilbert

2

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Sandra Thibault

3

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Jean-François Fortin

4

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Michel J Tremblay

5

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Europe PubMed Central

PMC publication ID

14 September 2017

language of work or name

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publication date

31 August 2009

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Europe PubMed Central

PMC publication ID

14 September 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

PMC publication ID

14 September 2017

53

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

11

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

4656-4666

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Human immunodeficiency virus type 1 (HIV-1) integration: a potential target for microbicides to prevent cell-free or cell-associated HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

HIV transfer between CD4 T cells does not require LFA-1 binding to ICAM-1 and is governed by the interaction of HIV envelope glycoprotein with CD4.

1 reference

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22 September 2017

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

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22 September 2017

Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Opposing roles of blood myeloid and plasmacytoid dendritic cells in HIV-1 infection of T cells: transmission facilitation versus replication inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Transition from rolling to firm adhesion can be mimicked by extension of integrin alphaLbeta2 in an intermediate affinity state

1 reference

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22 September 2017

Statins could be used to control replication of some viruses, including HIV-1.

1 reference

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22 September 2017

Regulation of LFA-1 activity through cytoskeleton remodeling and signaling components modulates the efficiency of HIV type-1 entry in activated CD4+ T lymphocytes

1 reference

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22 September 2017

Pleiotropic effects of statins

1 reference

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22 September 2017

Therapeutic antagonists and the conformational regulation of the beta2 integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Dangerous liaisons at the virological synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Statins inhibit HIV-1 infection by down-regulating Rho activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Susceptibility of HIV type 1 to the fusion inhibitor T-20 is reduced on insertion of host intercellular adhesion molecule 1 in the virus membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

The importance of virus-associated host ICAM-1 in human immunodeficiency virus type 1 dissemination depends on the cellular context.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

HLA-DR, ICAM-1, CD40, CD40L, and CD86 are incorporated to a similar degree into clinical human immunodeficiency virus type 1 variants expanded in natural reservoirs such as peripheral blood mononuclear cells and human lymphoid tissue cultured ex viv

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Rolling adhesion through an extended conformation of integrin alphaLbeta2 and relation to alpha I and beta I-like domain interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

B lymphocyte dysfunctions in HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Membranes as messengers in T cell adhesion signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Presence of Host ICAM-1 in Human Immunodeficiency Virus Type 1 Virions Increases Productive Infection of CD4 + T Lymphocytes by Favoring Cytosolic Delivery of Viral Material

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Modulating T cell responses for the treatment of psoriasis: a focus on efalizumab

1 reference

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22 September 2017

Structures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Leukocyte-endothelial interactions: clinical trials of anti-adhesion therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depletion in human lymphoid tissue, a major site of replication in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

A novel virus capture assay reveals a differential acquisition of host HLA-DR by clinical isolates of human immunodeficiency virus type 1 expanded in primary human cells depending on the nature of producing cells and the donor source

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Integrin antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells

1 reference

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22 September 2017

Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis

1 reference

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22 September 2017

Modulation of human immunodeficiency virus type 1-induced syncytium formation by the conformational state of LFA-1 determined by a new luciferase-based syncytium quantitative assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

1 reference

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22 September 2017

T Cells Expressing Activated LFA-1 Are More Susceptible to Infection with Human Immunodeficiency Virus Type 1 Particles Bearing Host-Encoded ICAM-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Host-derived ICAM-1 glycoproteins incorporated on human immunodeficiency virus type 1 are biologically active and enhance viral infectivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Host cell-dependent alterations in envelope components of human immunodeficiency virus type 1 virions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Quantitation of human immunodeficiency virus type 1 infection kinetics

1 reference

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22 September 2017

Ins and outs of LFA-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

Involvement of a leukocyte adhesion receptor (LFA-1) in HIV-induced syncytium formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

22 September 2017

The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

25 September 2017

Role of the leukocyte function antigen-1 conformational state in the process of human immunodeficiency virus type 1-mediated syncytium formation and virus infection

1 reference

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25 September 2017

HIV-1 virions produced from replicating peripheral blood lymphocytes are more infectious than those from nonproliferating macrophages due to higher levels of intravirion reverse transcripts: implications for pathogenesis and transmission

1 reference

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25 September 2017

The amount of host HLA-DR proteins acquired by HIV-1 is virus strain- and cell type-specific

1 reference

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25 September 2017

A simple and reliable method to detect cell membrane proteins on infectious human immunodeficiency virus type 1 particles.

1 reference

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15 June 2018

Functional Epitope Analysis of the Human CD 11 a/CD 18 Molecule (LFA-1, Lymphocyte Function-Associated Antigen 1) Involved in HIV-1-Induced Syncytium Formation

1 reference

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15 June 2018

The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester

1 reference

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17 June 2018

LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772324

20 August 2018

Allosteric LFA-1 inhibitors modulate natural killer cell function

1 reference

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20 August 2018

Adhesion molecule interactions facilitate human immunodeficiency virus type 1-induced virological synapse formation between T cells

1 reference

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20 August 2018

Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells

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20 August 2018

Statin blocks Rho/Rho-kinase signalling and disrupts the actin cytoskeleton: relationship to enhancement of LPS-mediated nitric oxide synthesis in vascular smooth muscle cells

1 reference

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20 August 2018

Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells.

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20 August 2018

Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

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20 August 2018

Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other

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20 August 2018

Transmission of HIV-1 infection between trophoblast placental cells and T-cells take place via an LFA-1-mediated cell to cell contact

1 reference

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20 August 2018

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

1 reference

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20 August 2018

Rapid and efficient cell-to-cell transmission of human immunodeficiency virus infection from monocyte-derived macrophages to peripheral blood lymphocytes.

1 reference

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20 August 2018

RANTES Stimulates Cell-Mediated Transmission of HIV-1 Infection

1 reference

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2 December 2018

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19721069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adhesion co-receptor expression and intracellular signalling in HIV disease: implications for immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19721069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Src and Syk tyrosine kinases in HIV-1 transfer from dendritic cells to CD4+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19721069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 upregulates intercellular adhesion molecule-1 gene expression in lymphoid tissue of patients with chronic HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/19721069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy, antagonism, and what the chequerboard puts between them

1 reference

https://pubmed.ncbi.nlm.nih.gov/19721069

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00117-09

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 September 2017

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