(Q39693828)

14 September 2017

title

L1CAM-integrin interaction induces constitutive NF-kappaB activation in pancreatic adenocarcinoma cells by enhancing IL-1beta expression (English)

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pancreatic adenocarcinoma

14 September 2017

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14 September 2017

H Kiefel

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14 September 2017

S Bondong

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14 September 2017

N Erbe-Hoffmann

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14 September 2017

J Hazin

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14 September 2017

S Riedle

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14 September 2017

J Wolf

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14 September 2017

M Pfeifer

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14 September 2017

H Schäfer

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14 September 2017

S Sebens Müerköster

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14 September 2017

P Altevogt

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14 September 2017

language of work or name

English

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publication date

14 June 2010

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14 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

page(s)

4766-4778

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Activation of cell-survival transcription factor NFkappaB in L1Ig6-stimulated endothelial cells

14 September 2017

cites work

1 reference

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Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

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Targeting cancer stem cells through L1CAM suppresses glioma growth

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L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer

31 March 2020

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Neural cell recognition molecule L1: from cell biology to human hereditary brain malformations

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Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

31 March 2020

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L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas.

31 March 2020

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L1 adhesion molecule (CD 171) in development and progression of human malignant melanoma

31 March 2020

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The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies

31 March 2020

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The RGD integrin binding site in human L1-CAM is important for nuclear signaling

31 March 2020

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L1 augments cell migration and tumor growth but not beta3 integrin expression in ovarian carcinomas

31 March 2020

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L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers

31 March 2020

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Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.

31 March 2020

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Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer

31 March 2020

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Kinetic analysis of L1 homophilic interaction: role of the first four immunoglobulin domains and implications on binding mechanism

31 March 2020

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ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles

31 March 2020

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Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells

31 March 2020

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Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

31 March 2020

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Structural and functional evolution of the L1 family: are four adhesion molecules better than one?

31 March 2020

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Enhanced L1CAM expression on pancreatic tumor endothelium mediates selective tumor cell transmigration

31 March 2020

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31 March 2020

Cancer statistics, 2007

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L1 is associated with micrometastatic spread and poor outcome in colorectal cancer

31 March 2020

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ILK, PINCH and parvin: the tIPP of integrin signalling

31 March 2020

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The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells

31 March 2020

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L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

31 March 2020

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The adhesion molecule L1 (CD171) promotes melanoma progression

31 March 2020

1 reference

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Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3

31 March 2020

1 reference

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Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Increased expression of the E3-ubiquitin ligase receptor subunit betaTRCP1 relates to constitutive nuclear factor-kappaB activation and chemoresistance in pancreatic carcinoma cells

31 March 2020

1 reference

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A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer

31 March 2020

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Antibodies directed against L1-CAM synergize with Genistein in inhibiting growth and survival pathways in SKOV3ip human ovarian cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Integrin and neurocan binding to L1 involves distinct Ig domains

31 March 2020

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Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements

31 March 2020

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ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling

31 March 2020

1 reference

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Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity

31 March 2020

1 reference

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Pancreatic cancer: basic and clinical aspects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

L1 on ovarian carcinoma cells is a binding partner for Neuropilin-1 on mesothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

The neural cell adhesion molecule L1 potentiates integrin-dependent cell migration to extracellular matrix proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.230

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.230

1 reference

14 September 2017

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