(Q39678666)

13 September 2017

title

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation (English)

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13 September 2017

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Chan Gao

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13 September 2017

Weipeng Cao

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13 September 2017

Lan Bao

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13 September 2017

Wei Zuo

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13 September 2017

Guoming Xie

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13 September 2017

Tiantian Cai

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13 September 2017

Wei Fu

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13 September 2017

Jian Zhang

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13 September 2017

Wei Wu

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13 September 2017

Xu Zhang

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13 September 2017

Ye-Guang Chen

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13 September 2017

publication date

18 July 2010

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13 September 2017

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13 September 2017

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13 September 2017

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13 September 2017

page(s)

781-790

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Autophagy: process and function

13 September 2017

cites work

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Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.

21 January 2018

1 reference

Autophagy: dual roles in life and death?

21 January 2018

1 reference

Overview of macroautophagy regulation in mammalian cells

21 January 2018

1 reference

Autophagy in the Pathogenesis of Disease

21 January 2018

1 reference

Role of autophagy in cancer

21 January 2018

1 reference

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

Autophagosome formation: core machinery and adaptations

21 January 2018

1 reference

WNT and beta-catenin signalling: diseases and therapies

21 January 2018

1 reference

Wnt/beta-catenin signaling in development and disease

21 January 2018

1 reference

The Wnt signaling pathway in development and disease

21 January 2018

1 reference

Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction

21 January 2018

1 reference

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

21 January 2018

1 reference

Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer

21 January 2018

1 reference

NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1.

21 January 2018

1 reference

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

21 January 2018

1 reference

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

The role of autophagy during the early neonatal starvation period

21 January 2018

1 reference

Dishevelled: The hub of Wnt signaling

21 January 2018

1 reference

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

1 reference

The selectivity of autophagy and its role in cell death and survival

21 January 2018

1 reference

Structural basis for sorting mechanism of p62 in selective autophagy

21 January 2018

1 reference

Structural basis of target recognition by Atg8/LC3 during selective autophagy

21 January 2018

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The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization

21 January 2018

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The Wnt signalling effector Dishevelled forms dynamic protein assemblies rather than stable associations with cytoplasmic vesicles.

21 January 2018

1 reference

A role for ubiquitin in selective autophagy

21 January 2018

1 reference

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

21 January 2018

1 reference

The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

21 January 2018

1 reference

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

21 January 2018

1 reference

Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL

21 January 2018

1 reference

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

21 January 2018

1 reference

Autophagy suppresses tumorigenesis through elimination of p62

21 January 2018

1 reference

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability

21 January 2018

1 reference

Down-regulation of Bax-interacting factor-1 in colorectal adenocarcinoma

21 January 2018

1 reference

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

21 January 2018

1 reference

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

21 January 2018

1 reference

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

Regulation mechanisms and signaling pathways of autophagy

21 January 2018

1 reference

Mammalian autophagy: core molecular machinery and signaling regulation

21 January 2018

1 reference

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

21 January 2018

1 reference

LC3 conjugation system in mammalian autophagy

21 January 2018

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Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

21 January 2018

1 reference

Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation

21 January 2018

1 reference

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

21 January 2018

1 reference

Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor

21 January 2018

1 reference

The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.

21 January 2018

1 reference

von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination

21 January 2018

1 reference

Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

21 January 2018

1 reference

Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus

21 January 2018

1 reference

Interaction with vesicle luminal protachykinin regulates surface expression of delta-opioid receptors and opioid analgesia

21 January 2018

1 reference

pVHL: a multipurpose adaptor protein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20639871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20639871

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB2082

1 reference

13 September 2017

1 reference