(Q39664674)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination (English)

1 reference

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11 February 2020

1 reference

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11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Zhenming Xu

1 reference

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11 February 2020

Zsolt Fulop

1 reference

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11 February 2020

Guikai Wu

1 reference

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11 February 2020

Egest J Pone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Thach Mai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Lisa M Thomas

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Ahmed Al-Qahtani

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Clayton A White

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Petra Steinacker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Zenggang Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

John Yates

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Bruce Herron

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Markus Otto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Hong Zan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Haian Fu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Paolo Casali

1 reference

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11 February 2020

publication date

22 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

Nature Structural & Molecular Biology

11 February 2020

published in

1 reference

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11 February 2020

volume

1 reference

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11 February 2020

issue

1 reference

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11 February 2020

page(s)

1124-1135

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 February 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3645988/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3645988/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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A coming-of-age story: activation-induced cytidine deaminase turns 10.

14 September 2017

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IgE in horses: occurrence in health and disease

14 September 2017

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Temporal regulation of Ig gene diversification revealed by single-cell imaging

14 September 2017

1 reference

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Multiple functions of MRN in end-joining pathways during isotype class switching

14 September 2017

1 reference

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S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination

14 September 2017

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14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response

14 September 2017

1 reference

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HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

14 September 2017

1 reference

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The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence

14 September 2017

1 reference

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Balancing AID and DNA repair during somatic hypermutation

14 September 2017

1 reference

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Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination

14 September 2017

1 reference

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Lupus-prone MRL/faslpr/lpr mice display increased AID expression and extensive DNA lesions, comprising deletions and insertions, in the immunoglobulin locus: concurrent upregulation of somatic hypermutation and class switch DNA recombination.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

14 September 2017

1 reference

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Sgamma3 switch sequences function in place of endogenous Sgamma1 to mediate antibody class switching

14 September 2017

1 reference

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Proteasomal degradation restricts the nuclear lifespan of AID

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Mechanism and regulation of class switch recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The biochemistry of somatic hypermutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

14-3-3 cruciform-binding proteins as regulators of eukaryotic DNA replication

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

IgH class switching and translocations use a robust non-classical end-joining pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Immunoglobulin somatic hypermutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Role of AID in tumorigenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Discovery of activation-induced cytidine deaminase, the engraver of antibody memory

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Regulation of AID expression in the immune response

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Targeting of somatic hypermutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

DNA repair in antibody somatic hypermutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Immunoglobulin gene diversification

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Inducible DNA breaks in Ig S regions are dependent on AID and UNG

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Unchanged survival rates of 14-3-3gamma knockout mice after inoculation with pathological prion protein

14 September 2017

1 reference

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Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Specificity of 14-3-3 isoform dimer interactions and phosphorylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Visualization of interactions among bZIP and Rel family proteins in living cells using bimolecular fluorescence complementation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Physiology of IgA and IgA deficiency

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

14-3-3 proteins: structure, function, and regulation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

DNA sequences at immunoglobulin switch region recombination sites

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

AID upmutants isolated using a high-throughput screen highlight the immunity/cancer balance limiting DNA deaminase activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

AID-dependent generation of resected double-strand DNA breaks and recruitment of Rad52/Rad51 in somatic hypermutation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Shotgun protein identification and quantification by mass spectrometry.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Active nuclear import and cytoplasmic retention of activation-induced deaminase

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

AID is required for germinal center-derived lymphomagenesis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

MRE11/RAD50 cleaves DNA in the AID/UNG-dependent pathway of immunoglobulin gene diversification

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

An evolutionarily conserved target motif for immunoglobulin class-switch recombination

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Mutations in the hydrophobic surface of an amphipathic groove of 14-3-3zeta disrupt its interaction with Raf-1 kinase

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645988

Insights into DNA deaminases

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.1884

Spontaneously hypertensive rat: cholera toxin converts suppression to immunity through a Th2 cell-IL-4 pathway

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20729863

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NSMB.1884

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

release_5cgqzvwkffhqfms6mwwyere4bm

11 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5cgqzvwkffhqfms6mwwyere4bm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

20729863

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20729863%20AND%20SRC:MED&resulttype=core&format=json