(Q39461570)

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Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model

scientific article published on March 2013

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1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

1 reference

ChEBI release 2020-05-28

Karin Scharffetter-Kochanek

10

object named as

Karin Scharffetter-Kochanek

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

Bernd L Fiebich

9

object named as

Bernd L Fiebich

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

author name string

Agatha Stegemann

1

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Europe PubMed Central

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12 September 2017

Anca Sindrilaru

2

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Europe PubMed Central

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12 September 2017

Beate Eckes

3

1 reference

Europe PubMed Central

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12 September 2017

Adriana del Rey

4

1 reference

Europe PubMed Central

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12 September 2017

Alexander Heinick

5

1 reference

Europe PubMed Central

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12 September 2017

Jan S Schulte

6

1 reference

Europe PubMed Central

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12 September 2017

Frank U Müller

7

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Europe PubMed Central

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12 September 2017

Sergei A Grando

8

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12 September 2017

Thomas A Luger

11

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12 September 2017

Markus Böhm

12

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12 September 2017

publication date

1 March 2013

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12 September 2017

Arthritis & Rheumatology

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12 September 2017

65

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Europe PubMed Central

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12 September 2017

3

1 reference

Europe PubMed Central

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12 September 2017

792-804

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Europe PubMed Central

PubMed publication ID

12 September 2017

TGF-beta signaling and the fibrotic response

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Scleroderma: from pathophysiology to novel therapeutic approaches

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Collagen metabolism is a novel target of the neuropeptide alpha-melanocyte-stimulating hormone.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Treatment of Raynaud's phenomenon with the selective serotonin reuptake inhibitor fluoxetine

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Platelet-derived serotonin links vascular disease and tissue fibrosis

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Fibrosis and carcinoid syndrome: from causation to future therapy

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Cutaneous scleroderma in association with carcinoid syndrome

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Scleroderma and the carcinoid syndrome

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Functional activity of serotoninergic and melatoninergic systems expressed in the skin

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Hydroxychloroquine modulates metabolic activity and proliferation and induces autophagic cell death of human dermal fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

5-Hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Relationship between alpha 7 nAChR and apoptosis in human lymphocytes.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Tobacco-specific carcinogen enhances colon cancer cell migration through alpha7-nicotinic acetylcholine receptor.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Control of connective tissue gene expression by TGF beta: role of Smad proteins in fibrosis.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

TGF-beta-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Transforming growth factor-beta signaling through the Smad proteins: role in systemic sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5‐HT3C, 5‐HT3D, and 5‐HT3E

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Distribution of serotonin receptors and interacting proteins in the human sigmoid colon.

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Molecular dissection of tropisetron, an alpha7 nicotinic acetylcholine receptor-selective partial agonist

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

The α-Bungarotoxin-binding Nicotinic Acetylcholine Receptor from Rat Brain Contains Only the α7 Subunit

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Nicotinic acetylcholine receptors on hippocampal neurons: distribution on the neuronal surface and modulation of receptor activity

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

The non-neuronal cholinergic system of human skin

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Receptor-mediated tobacco toxicity: cooperation of the Ras/Raf-1/MEK1/ERK and JAK-2/STAT-3 pathways downstream of alpha7 nicotinic receptor in oral keratinocytes

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Green tea polyphenol epigallocatechin-3-gallate suppresses collagen production and proliferation in keloid fibroblasts via inhibition of the STAT3-signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor α7 subunit gene knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Cytokine-Induced Alterations of α7 Nicotinic Receptor in Colonic CD4 T Cells Mediate Dichotomous Response to Nicotine in Murine Models of Th1/Th17- versus Th2-Mediated Colitis

1 reference

https://api.crossref.org/works/10.1002%2FART.37809

21 January 2018

Identifiers

10.1002/ART.37809

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 September 2017

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