(Q39101616)

9 September 2017

title

Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase (English)

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pancreatic adenocarcinoma

9 September 2017

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N Weizman

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9 September 2017

Y Krelin

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9 September 2017

A Shabtay-Orbach

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9 September 2017

M Amit

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9 September 2017

Y Binenbaum

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9 September 2017

R J Wong

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9 September 2017

Z Gil

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9 September 2017

language of work or name

English

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publication date

2 September 2013

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

page(s)

3812-3819

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Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 study

9 September 2017

cites work

1 reference

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Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma

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Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial

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Pharmacogenetics of anticancer drug sensitivity in pancreatic cancer

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c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK.

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Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis

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Pancreatic cancer-associated stroma production

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Implication of tumor microenvironment in the resistance to chemotherapy in breast cancer patients

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Macrophages, innate immunity and cancer: balance, tolerance, and diversity

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https://api.crossref.org/works/10.1038%2FONC.2013.357

Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.357

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

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Microenvironmental regulation of metastasis

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Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves.

21 January 2018

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Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.357

Bone marrow stromal-derived soluble factors and direct cell contact contribute to de novo drug resistance of myeloma cells by distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis

21 January 2018

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The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance

21 January 2018

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

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Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

21 January 2018

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Phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in progressive or recurrent ovarian cancer

21 January 2018

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Role of checkpoint kinase 1 in preventing premature mitosis in response to gemcitabine

21 January 2018

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TGF-β1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells

21 January 2018

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Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth.

21 January 2018

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Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response

21 January 2018

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Gene expression profiling of liver metastases and tumour invasion in pancreatic cancer using an orthotopic SCID mouse model

21 January 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2013.357

"In vivo" depletion of macrophages by liposome-mediated "suicide".

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Chemotherapeutic resistance: surviving stressful situations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Recruitment of myeloid but not endothelial precursor cells facilitates tumor regrowth after local irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

CXCL12–CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Stromal responses to carcinomas of the pancreas: juxtatumoral gene expression conforms to the infiltrating pattern and not the biologic subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Cancer: Macrophages limit chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Dynamics of the immune reaction to pancreatic cancer from inception to invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Secretion of functional hematopoietic growth factors by human carcinoma cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

Inflammation and necrosis promote tumour growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.357

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.357

1 reference

9 September 2017

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