(Q39085008)

8 September 2017

title

Understanding Parkinson's Disease through the Use of Cell Reprogramming (English)

1 reference

8 September 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Rebecca Playne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

1 reference

12 January 2017

1 reference

Stem Cell Reviews and Reports

8 September 2017

published in

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8 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

151-169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json

Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

10 June 2020

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Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in parkinsonian rats

21 January 2018

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Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

21 January 2018

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Gli1 is an inducing factor in generating floor plate progenitor cells from human embryonic stem cells

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21 January 2018

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Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors

21 January 2018

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Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis

21 January 2018

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Efficient derivation of functional floor plate tissue from human embryonic stem cells

21 January 2018

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Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions

21 January 2018

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Specification of midbrain dopamine neurons from primate pluripotent stem cells

21 January 2018

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Glycogen synthase kinase 3β and activin/nodal inhibition in human embryonic stem cells induces a pre-neuroepithelial state that is required for specification to a floor plate cell lineage.

21 January 2018

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Cerebral organoids model human brain development and microcephaly

21 January 2018

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Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons

21 January 2018

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Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons

21 January 2018

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Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

21 January 2018

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iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease

21 January 2018

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Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation

21 January 2018

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Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Autologous iPSC-derived dopamine neuron transplantation in a nonhuman primate Parkinson's disease model

21 January 2018

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Identification of intrinsic determinants of midbrain dopamine neurons

21 January 2018

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Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells

21 January 2018

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Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells

21 January 2018

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Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype.

21 January 2018

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Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors

21 January 2018

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Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons

21 January 2018

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Cytoplasmic activation of human nuclear genes in stable heterocaryons

21 January 2018

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Expression of a single transfected cDNA converts fibroblasts to myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of fibroblasts to functional neurons by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of induced neuronal cells by the single reprogramming factor ASCL1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

MicroRNA-mediated conversion of human fibroblasts to neurons.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct Conversion of Normal and Alzheimer's Disease Human Fibroblasts into Neuronal Cells by Small Molecules

21 January 2018

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Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of human fibroblasts to dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct reprogramming of mouse fibroblasts to neural progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of fibroblasts into stably expandable neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Zic3 induces conversion of human fibroblasts to stable neural progenitor-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct reprogramming of human astrocytes into neural stem cells and neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Induced neural stem cells generated from rat fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of integration-free neural progenitor cells from cells in human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of integration-free and region-specific neural progenitors from primate fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of primitive neural stem cells from human fibroblasts using a defined set of factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct reprogramming of fibroblasts into neural stem cells by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of dopaminergic neurons directly from mouse fibroblasts and fibroblast-derived neural progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of dermal fibroblasts into neural progenitor cells by a novel cocktail of defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Characterization of induced neural progenitors from skin fibroblasts by a novel combination of defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of human fibroblasts into dopaminergic neural progenitor-like cells using TAT-mediated protein transduction of recombinant factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Induction of Neural Progenitor-Like Cells from Human Fibroblasts via a Genetic Material-Free Approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

FGF8 is Essential for Functionality of Induced Neural Precursor Cell-derived Dopaminergic Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of Dopamine Neurons from Rodent Fibroblasts through the Expandable Neural Precursor Cell Stage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Direct conversion of human fibroblasts into neuronal restricted progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of neural progenitor cells by chemical cocktails and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Virtual karyotyping reveals greater chromosomal stability in neural cells derived by transdifferentiation than those from stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Concise review: the involvement of SOX2 in direct reprogramming of induced neural stem/precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

RNA-based tools for nuclear reprogramming and lineage-conversion: towards clinical applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Genetic correction of a LRRK2 mutation in human iPSCs links parkinsonian neurodegeneration to ERK-dependent changes in gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Interplay of LRRK2 with chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Human iPSC-based modeling of late-onset disease via progerin-induced aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Programming and Reprogramming Cellular Age in the Era of Induced Pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Rapid single-step induction of functional neurons from human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Enhanced Rejuvenation in Induced Pluripotent Stem Cell-Derived Neurons Compared with Directly Converted Neurons from an Aged Mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-017-9717-5

Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency

21 January 2018

1 reference

12 December 2020

Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: effect of in vitro differentiation on graft survival and teratoma formation

1 reference

12 December 2020

Induction of human neuronal cells by defined transcription factors

1 reference

12 December 2020

Generating regionalized neuronal cells from pluripotency, a step-by-step protocol

1 reference

12 December 2020

Direct generation of neurosphere-like cells from human dermal fibroblasts

1 reference

12 December 2020

Non-Viral Generation of Neural Precursor-like Cells from Adult Human Fibroblasts

1 reference

12 December 2020

Reversal of X-inactivation in female mouse somatic cells hybridized with murine teratocarcinoma stem cells in vitro

1 reference

12 December 2020

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

1 reference

12 December 2020

10.1007/S12015-017-9717-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28083784%20AND%20SRC:MED&resulttype=core&format=json