(Q38724669)

English

Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway

scientific article published on 21 December 2016

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6272965

Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway (English)

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6272965

Ligustrum lucidum

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Ligustrum lucidum

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inferred from title

1

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8 June 2020

author name string

Xiao Ke

2

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8 June 2020

Wei Fu

3

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8 June 2020

Xiaoping Gao

4

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8 June 2020

Hongcheng Zhang

5

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8 June 2020

Wei Wang

6

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8 June 2020

Na Ma

7

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8 June 2020

Manxi Zhao

8

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8 June 2020

Xiaofeng Hao

9

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Europe PubMed Central

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8 June 2020

Zhirong Zhang

10

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8 June 2020

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publication date

21 December 2016

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6272965

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28009852%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

21

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8 June 2020

12

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8 June 2020

copyright license

Creative Commons Attribution 4.0 International

21 December 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Influence of an aqueous extract of Ligustrum lucidum and an ethanol extract of Schisandra chinensis on parameters of antioxidative metabolism and spleen lymphocyte proliferation of broilers

1 reference

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Antioxidative glucosides from the fruits of Ligustrum lucidum

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21 January 2018

Ligustrum lucidum Ait. fruit extract induces apoptosis and cell senescence in human hepatocellular carcinoma cells through upregulation of p21.

1 reference

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21 January 2018

New secoiridoid glucosides from Ligustrum lucidum induce ERK and CREB phosphorylation in cultured cortical neurons

1 reference

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21 January 2018

Antidiabetic and antioxidant effects of oleanolic acid from Ligustrum lucidum Ait in alloxan-induced diabetic rats

1 reference

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21 January 2018

Antidiabetic potential of oleanolic acid from Ligustrum lucidum Ait.

1 reference

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21 January 2018

Hepatoprotective action of an oleanolic acid-enriched extract of Ligustrum lucidum fruits is mediated through an enhancement on hepatic glutathione regeneration capacity in mice

1 reference

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21 January 2018

In vitro evaluation of secoiridoid glucosides from the fruits of Ligustrum lucidum as antiviral agents

1 reference

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21 January 2018

Bioactivity-guided Isolation of antiosteoporotic compounds from Ligustrum lucidum

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Quality assessment of Fructus Ligustri Lucidi by the simultaneous determination of six compounds and chemometric analysis.

1 reference

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21 January 2018

New Therapeutic Approaches in Diabetic Retinopathy

1 reference

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21 January 2018

Hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina is suppressed by HIF-1α destabilization by SH-1242 and SH-1280, novel hsp90 inhibitors

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Inhibition of EGF signaling protects the diabetic retina from insulin-induced vascular leakage

1 reference

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21 January 2018

Zeaxanthin inhibits hypoxia-induced VEGF secretion by RPE cells through decreased protein levels of hypoxia-inducible factors-1α.

1 reference

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21 January 2018

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function

1 reference

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21 January 2018

Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature

1 reference

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21 January 2018

Transcriptional regulation of the Vascular Endothelial Growth Factor gene--a concert of activating factors

1 reference

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21 January 2018

Hypoxia-inducible factor (HIF)/vascular endothelial growth factor (VEGF) signaling in the retina

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Deguelin inhibits retinal neovascularization by down-regulation of HIF-1alpha in oxygen-induced retinopathy

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Pleiotropic effects of YC-1 selectively inhibit pathological retinal neovascularization and promote physiological revascularization in a mouse model of oxygen-induced retinopathy

1 reference

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21 January 2018

Sustained delivery of a HIF-1 antagonist for ocular neovascularization

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Oxygen-induced retinopathy in the rat model

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Induction of VEGFA mRNA translation by CoCl2 mediated by HuR.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

HIF-1α pathway: role, regulation and intervention for cancer therapy

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Effects of modified LDL and HDL on retinal pigment epithelial cells: a role in diabetic retinopathy?

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathy.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Different Expression of Hypoxic and Angiogenic Factors in Human Endometriotic Lesions

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Regulation of erythropoietin production

1 reference

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21 January 2018

HIF-1 alpha: a key survival factor for serum-deprived prostate cancer cells

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Hypoxic upregulation of arginase II in human lung endothelial cells

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21121756

21 January 2018

Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors

1 reference

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21 January 2018

Modeling the interplay between the HIF-1 and p53 pathways in hypoxia

1 reference

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21 January 2018

Heat-shock-protein 90 protects from downregulation of HIF-1α in calcineurin-induced myocardial hypertrophy.

1 reference

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21 January 2018

Influence of the difference of breastfeeding volume on a rat model of oxygen-induced retinopathy

1 reference

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21 January 2018

Impairment of extramitochondrial oxidative phosphorylation in mouse rod outer segments by blue light irradiation

1 reference

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21 January 2018

Isolation and identification of two new secoiridoids of water-soluble chemical constituents from the fruits of Ligustrum lucidum Ait

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extract and identify ingredient from Ligustrum Lucidum Ait and study its effect to periodontal pathogen.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct Transcriptional Up-regulation of Cyclooxygenase-2 by Hypoxia-Inducible Factor (HIF)-1 Promotes Colorectal Tumor Cell Survival and Enhances HIF-1 Transcriptional Activity during Hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of Ligustrum lucidum fruit extract on acute butylated hydroxytoluene-induced oxidative stress in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seasonal variations in metabolite profiling of the fruits of Ligustrum lucidum Ait

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Hypoxia-inducible factor 1-α and vascular endothelial growth factor-C in locally advanced breast cancer patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro immunomodulatory effects of an oleanolic acid-enriched extract of Ligustrum lucidum fruit (Ligustrum lucidum supercritical CO2 extract) on piglet immunocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New secoiridoids from the fruits of Ligustrum lucidum Ait with triglyceride accumulation inhibitory effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active components of Ligustrum lucidum inhibiting hepatitis C virus replicase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-hyperoxia paradigms in the development of oxygen-induced retinopathy in a rat pup model

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-obesity effect of (8-E)-niizhenide, a secoiridoid from Ligustrum lucidum, in high-fat diet-induced obese mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of experimental atherosclerosis in rabbits with Ligustrum lucidum fruit

1 reference

https://pubmed.ncbi.nlm.nih.gov/28009852

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES21121756

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28009852%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28009852%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28009852%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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