(Q38550879)

4 September 2017

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title

Drug and environmental factors associated with adverse pregnancy outcomes. Part I: Antiepileptic drugs, contraceptives, smoking, and folate (English)

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4 September 2017

D P Lewis

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4 September 2017

D C Van Dyke

series ordinal

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4 September 2017

P J Stumbo

series ordinal

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4 September 2017

M J Berg

series ordinal

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4 September 2017

language of work or name

English

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publication date

1 July 1998

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Annals of Pharmacotherapy

4 September 2017

published in

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4 September 2017

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4 September 2017

issue

7-8

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4 September 2017

page(s)

802-817

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The fetal hydantoin syndrome

4 September 2017

cites work

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Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 2: Human studies

21 January 2018

1 reference

Phenytoin-folic acid interaction

21 January 2018

1 reference

Maternal serum folacin levels during and after normal pregnancy

21 January 2018

1 reference

Periconceptional folic acid supplementation as a social intervention

21 January 2018

1 reference

The role of nutrition in neural tube defects

21 January 2018

1 reference

Evidence for multi-site closure of the neural tube in humans

21 January 2018

1 reference

The epidemiology of neural tube defects: a review of dietary intake and related factors as etiologic agents

21 January 2018

1 reference

Impact of prenatal diagnosis and elective termination on prevalence and risk estimates of neural tube defects in California, 1989-1991.

21 January 2018

1 reference

Hispanic origin and neural tube defects in Houston/Harris County, Texas. I. Descriptive epidemiology

21 January 2018

1 reference

Spina bifida and parental occupation

21 January 2018

1 reference

Looking for causes of neural tube defects: where does the environment fit in?

21 January 2018

1 reference

Case-control study of congenital defects and parental employment in health care.

21 January 2018

1 reference

Maternal Heat Exposure and Neural Tube Defects

21 January 2018

1 reference

Involvement of deprivation and environmental lead in neural tube defects: a matched case-control study

21 January 2018

1 reference

Teratogenicity of high vitamin A intake.

21 January 2018

1 reference

Pantothenic acid decreases valproic acid-induced neural tube defects in mice (I).

21 January 2018

1 reference

Risk of neural tube defect-affected pregnancies among obese women

21 January 2018

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Prepregnant weight in relation to risk of neural tube defects

21 January 2018

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Maternal serum folate and vitamin B12 concentrations in pregnancies associated with neural tube defects

21 January 2018

1 reference

Maternal vitamin levels during pregnancies producing infants with neural tube defects

21 January 2018

1 reference

The methylfolate axis in neural tube defects: in vitro characterisation and clinical investigation.

21 January 2018

1 reference

Folic acid absorption in women with a history of pregnancy with neural tube defect

21 January 2018

1 reference

Multi-institutional study on the teratogenicity and fetal toxicity of antiepileptic drugs: a report of a collaborative study group in Japan

21 January 2018

1 reference

Family studies in fetal phenytoin exposure

21 January 2018

1 reference

Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy

21 January 2018

1 reference

The effects of prenatal exposure to phenytoin and other anticonvulsants on intellectual function at 4 to 8 years of age

21 January 2018

1 reference

Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies

21 January 2018

1 reference

The fetal hydantoin syndrome: answers from a mouse model.

21 January 2018

1 reference

Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding

21 January 2018

1 reference

The effect of pregnancy in humans on the pharmacokinetics of stable isotope labelled phenytoin

21 January 2018

1 reference

Prenatal prediction of risk of the fetal hydantoin syndrome

21 January 2018

1 reference

Phenytoin teratogenicity and effects on embryonic and maternal folate metabolism [published errtum appears in Teratology 1986 Dec;34(3):487]

21 January 2018

1 reference

Pattern of malformations in the children of women treated with carbamazepine during pregnancy

21 January 2018

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Spina bifida in infants of women treated with carbamazepine during pregnancy

21 January 2018

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Antiepileptic medication in pregnancy: late effects on the children's central nervous system development.

21 January 2018

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Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy

21 January 2018

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Interactions between folates and carbamazepine or valproate in the rat.

21 January 2018

1 reference

Valproic Acid-Induced Neural Tube Defects in Mouse and Human: Aspects of Chirality, Alternative Drug Development, Pharmacokinetics and Possible Mechanisms

21 January 2018

1 reference

The fetal valproate syndrome

21 January 2018

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Fetal growth, major malformations, and minor anomalies in infants born to women receiving valproic acid

21 January 2018

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Verification of the fetal valproate syndrome phenotype

21 January 2018

1 reference

Malformations, withdrawal manifestations, and hypoglycaemia after exposure to valproate in utero

21 January 2018

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Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome

21 January 2018

1 reference

Antiepileptic drugs alter endogenous retinoid concentrations: A possible mechanism of teratogenesis of anticonvulsant therapy

21 January 2018

1 reference

Effects of exposure to benzodiazepine during fetal life.

21 January 2018

1 reference

Neurodevelopment in late infancy after prenatal exposure to benzodiazepines--a prospective study

21 January 2018

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Growth retardation, dysmorphic facies and minor malformations following massive exposure to phenobarbitone in utero.

21 January 2018

1 reference

A possible primidone embryopathy

21 January 2018

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Outcomes of pregnancy associated with antiepileptic drugs

21 January 2018

1 reference

In utero exposure to phenobarbital and intelligence deficits in adult men.

21 January 2018

1 reference

Folate Metabolism and the Anticonvulsant Efficacy of Phenobarbital

21 January 2018

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Changes in hepatic folylpolyglutamate pattern in phenobarbitone-treated rats

21 January 2018

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Effect of chronic primidone treatment on folate-dependent one-carbon metabolism in the rat

21 January 2018

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Lamotrigine: an antiepileptic agent for the treatment of partial seizures

21 January 2018

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Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication

21 January 2018

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Gabapentin: a new agent for the management of epilepsy

21 January 2018

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Genetic predisposition to phenytoin-induced birth defects

21 January 2018

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Maternal drug histories and congenital malformations: limb reduction defects and oral clefts

21 January 2018

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Serum folic acid levels in epileptic mothers and their relationship to congenital malformations

21 January 2018

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Drugs and folate metabolism

21 January 2018

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Use of oral contraceptives by women with epilepsy

21 January 2018

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Vitamin and trace mineral metabolism in medroxyprogesterone acetate users

21 January 2018

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Anencephaly and ovulation stimulation.

21 January 2018

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Risk of neural tube defects in relation to maternal fertility and fertility drug use.

21 January 2018

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Chronic treatment of rats with primidone causes depletion of pteroylpentaglutamates in liver

21 January 2018

1 reference

Folic acid safety and toxicity: a brief review

21 January 2018

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Neural tube defects--why are rates high among populations of Mexican descent?

21 January 2018

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Benzodiazepine Amplification of Valproate Teratogenic Effects in Children of Mothers with Absence Epilepsy

21 January 2018

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Congenital abnormalities in two sibs exposed to valproic acid in utero

21 January 2018

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An assessment of serum and red blood cell folate concentrations in patients with epilepsy on lamotrigine therapy

21 January 2018

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Anticonvulsant drugs and congenital abnormalities

21 January 2018

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Risks to the offspring of women treated with hydantoin anticonvulsants, with emphasis on the fetal hydantoin syndrome

21 January 2018

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Plasma folate adequacy as determined by homocysteine level

21 January 2018

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Folate levels and neural tube defects. Implications for prevention

21 January 2018

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Accelerated folate breakdown in pregnancy

21 January 2018

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Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

21 January 2018

1 reference

Hispanic origin and neural tube defects in Houston/Harris County, Texas. II. Risk factors

21 January 2018

1 reference

Periconceptional folate supplementation and neural tube defects

21 January 2018

1 reference

Vitamin A concentration in amniotic fluid and maternal serum related to neural-tube defects

21 January 2018

1 reference

The effects of various levels of dietary protein on retinoic acid-induced teratogenicity in rats

21 January 2018

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Vitamin B12 and anencephaly

21 January 2018

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Dehydroepiandrosterone sulfate and testosterone are independently associated with body fat distribution in premenopausal women

21 January 2018

1 reference

Survival of infants with neural tube defects in Western Australia 1966-1990

21 January 2018

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Open spina bifida: outcome for a complete cohort treated unselectively and followed into adulthood

21 January 2018

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Is disordered folate metabolism the basis for the genetic predisposition to neural tube defects?

21 January 2018

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Investigation of folate intake and metabolism in women who have had two pregnancies complicated by neural tube defects.

21 January 2018

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Maternal-Fetal Folate Status and Neural Tube Defects: A Case Control Study

21 January 2018

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Local and systemic effects of cigarette smoking on folate and vitamin B-12

21 January 2018

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Influence of smoking on folate intake and blood folate concentrations in a group of elderly Spanish men

21 January 2018

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Folate, carotene, and smoking.

21 January 2018

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Serum folic acid levels and antipyrine clearance rates in smokers and non-smokers

21 January 2018

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Epilepsy and pregnancy: a prospective study of seizure control in relation to free and total plasma concentrations of carbamazepine and phenytoin

21 January 2018

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Disposition of carbamazepine and phenytoin in pregnancy

21 January 2018

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Plasma antiepileptic drug concentrations during pregnancy

21 January 2018

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Phenytoin-folic acid: a review.

21 January 2018

1 reference

Phenytoin metabolism during pregnancy

21 January 2018

1 reference

Protection from phenytoin-induced congenital malformations by coadministration of the antiepileptic drug stiripentol in a mouse model

21 January 2018

1 reference

[Embryofetopathy due to valproate: a pathology only little known. Apropos of 4 cases]

21 January 2018

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Teratogenicity of antiepileptic drug combinations with special emphasis on epoxidation (of carbamazepine)

21 January 2018

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Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation

21 January 2018

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21 January 2018

Fetal valproate syndrome

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Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs.

21 January 2018

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Teratogenic effects of benzodiazepine use during pregnancy

21 January 2018

1 reference

Four siblings with similar malformations after exposure to phenytoin and primidone

21 January 2018

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Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.

21 January 2018

1 reference

Inhibition of epoxide hydrolase by anticonvulsants and risk of teratogenicity

21 January 2018

1 reference

Lamotrigine-induced carbamazepine toxicity: an interaction with carbamazepine-10,11 -epoxide

21 January 2018

1 reference

21 January 2018

1 reference

Effects of felbamate on the pharmacokinetics of phenobarbital

21 January 2018

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21 January 2018

1 reference

Fetal hydantoin syndrome in triplets. A unique experiment of nature

21 January 2018

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Discordant expression of fetal hydantoin syndrome in heteropaternal dizygotic twins

21 January 2018

1 reference

Spina bifida and cleft lip among newborns of Norwegian women with epilepsy: changes related to the use of anticonvulsants

21 January 2018

1 reference

Anticonvulsants, folate levels, and pregnancy outcome: a prospective study

21 January 2018

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Effects of oral contraceptives on vitamins B6, B12, C, and folacin

21 January 2018

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Sub-50 oral contraceptives affect folate kinetics

21 January 2018

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Evidence against oral contraceptives as a cause of neural-tube defects

21 January 2018

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Oral contraception and congenital abnormalities.

21 January 2018

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The outcome of pregnancy in former oral contraceptive users

21 January 2018

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Role of oral contraception in congenital malformations of offspring

21 January 2018

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Letter: Ovulation stimulation and defects of neural-tube closure

21 January 2018

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Possible relationship between clomiphene and neural tube defects

21 January 2018

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Anencephaly and ovulation stimulation

21 January 2018

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Outcome of pregnancy after clomiphene therapy

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Congenital malformations of newborn infants after clomiphene-induced ovulation.

21 January 2018

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Clomiphene citrate and neural tube defects: a pooled analysis of controlled epidemiologic studies and recommendations for future studies

21 January 2018

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21 January 2018

Identifiers

DOI

10.1345/APH.17297

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4 September 2017

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