(Q38451773)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis (English)

1 reference

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1 March 2020

1 reference

1 reference

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Chunying Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Kristen E N Scott

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Michael D Cameron

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Mohammad Fallahi

1 reference

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1 March 2020

Weimin Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Mark A Hall

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Jitendra K Mishra

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Fangzheng Li

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Heide Marika Genau

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Robert J Rounbehler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Yunqi Lu

1 reference

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1 March 2020

K Ganesh Kumar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Andrew A Butler

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Thomas D Bannister

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Andrea T Hooper

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Keziban Unsal-Kacmaz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

William R Roush

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

John L Cleveland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

27 November 2013

1 reference

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1 March 2020

1 reference

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1 March 2020

volume

1 reference

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1 March 2020

issue

1 reference

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1 March 2020

page(s)

908-920

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

1 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Transcriptional amplification in tumor cells with elevated c-Myc.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Role of monocarboxylate transporters in human cancers: state of the art.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Cell-type independent MYC target genes reveal a primordial signature involved in biomass accumulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Metformin and cancer: new applications for an old drug

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Immunity, Inflammation, and Cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Understanding the Warburg effect: the metabolic requirements of cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Tumor cell metabolism: cancer's Achilles' heel

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Lactate favours the dissociation of skeletal muscle 6-phosphofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

On the Origin of Cancer Cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Repression of p15INK4b expression by Myc through association with Miz-1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

c-Myc transactivation of LDH-A: implications for tumor metabolism and growth

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Lactate dehydrogenase M-subunit deficiency: a new type of hereditary exertional myopathy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Monocarboxylate transporter MCT1 is a target for immunosuppression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Cell cycle activation by c-myc in a burkitt lymphoma model cell line.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

DNA methylation of the SLC16A3 promoter regulates expression of the human lactate transporter MCT4 in renal cancer with consequences for clinical outcome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Global gene expression analysis reveals specific patterns of cell junctions in non-small cell lung cancer subtypes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3946415

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

31 August 2018

1 reference

12 December 2020

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

12 December 2020

LACTIC DEHYDROGENASES: FUNCTIONS OF THE TWO TYPES RATES OF SYNTHESIS OF THE TWO MAJOR FORMS CAN BE CORRELATED WITH METABOLIC DIFFERENTIATION

1 reference

12 December 2020

Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number

1 reference

12 December 2020

Optimization of monocarboxylate transporter 1 blockers through analysis and modulation of atropisomer interconversion properties

1 reference

12 December 2020

MUC12 mRNA expression is an independent marker of prognosis in stage II and stage III colorectal cancer

1 reference

12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

1 reference

12 December 2020

10.1158/0008-5472.CAN-13-2034

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24285728

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24285728%20AND%20SRC:MED&resulttype=core&format=json