(Q38308128)

2 September 2017

title

Role of heteroduplex joints in the functional interactions between human Rad51 and wild-type p53. (English)

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2 September 2017

Süsse S

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2 September 2017

Janz C

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2 September 2017

Janus F

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2 September 2017

Deppert W

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2 September 2017

Wiesmüller L

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2 September 2017

language of work or name

English

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publication date

1 September 2000

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2 September 2017

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2 September 2017

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2 September 2017

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2 September 2017

page(s)

4500-4512

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p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.

2 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

21 January 2018

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The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A

21 January 2018

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Heteroduplex formation by human Rad51 protein: effects of DNA end-structure, hRP-A and hRad52.

21 January 2018

1 reference

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One-sided invasion events in homologous recombination at double-strand breaks

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Interaction of p53 with the human Rad51 protein

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Recombinational crossroads: Eukaryotic enzymes and the limits of bacterial precedents

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Expression of Wild-type p53 Is Required for Efficient Global Genomic Nucleotide Excision Repair in UV-irradiated Human Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Terminal deoxyribonucleotidyl transferase (EC 2.7.7.31).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Activities of human recombination protein Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Human Rad51 protein can form homologous joints in the absence of net strand exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Rapid exchange of A:T base pairs is essential for recognition of DNA homology by human Rad51 recombination protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

DNA recombination: the replication connection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Excision of mismatched nucleotides from DNA: a potential mechanism for enhancing DNA replication fidelity by the wild-type p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Increased UV-induced SCEs but normal repair of DNA damage in p53-deficient mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The dual role model for p53 in maintaining genomic integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Different regulation of the p53 core domain activities 3'-to-5' exonuclease and sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

p53-mediated DNA renaturation can mimic strand exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The hRad51 and RecA proteins show significant differences in cooperative binding to single-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Biochemistry of Genetic Recombination: Energetics and Mechanism of DNA Strand Exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Surface plasmon resonance measurements reveal stable complex formation between p53 and DNA polymerase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Cancer. p53, guardian of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Model for Homologous Recombination During Transfer of DNA into Mouse L Cells: Role for DNA Ends in the Recombination Process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Intermolecular recombination between DNAs introduced into mouse L cells is mediated by a nonconservative pathway that leads to crossover products

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The BRCA2 gene product functionally interacts with p53 and RAD51

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

How p53 binds DNA as a tetramer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Inactivation of p53 results in high rates of homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Mismatch repair in replication fidelity, genetic recombination, and cancer biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Structure and function of the multifunctional DNA-repair enzyme exonuclease III

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Brca1 controls homology-directed DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Characterization of Strand Exchange Activity of Yeast Rad51 Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Interaction of Rad51 with ATP and Mg2+ induces a conformational change in Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Rad51 uses one mechanism to drive DNA strand exchange in both directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

BRCA1 regulates p53-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Effect of transition metals on binding of p53 protein to supercoiled DNA and to consensus sequence in DNA fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Two Pathways for Removal of Nonhomologous DNA Ends during Double-Strand Break Repair in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The RecA protein: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

GTPase-activating proteins: helping hands to complement an active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Regulation of CAK kinase activity by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Association of BRCA1 with Rad51 in mitotic and meiotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Binding of double-strand breaks in DNA by human Rad52 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

The multistep nature of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

p53 domains: identification and characterization of two autonomous DNA-binding regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

p53 domains: structure, oligomerization, and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

p53 modulation of TFIIH–associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Enzymes and molecular mechanisms of genetic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Elevated Recombination in Immortal Human Cells Is Mediated by HsRAD51 Recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

From competition to collaboration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

Dissociation of the recombination control and the sequence-specific transactivation function of P53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

A genetic study of x-ray sensitive mutants in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

Faulty DNA polymerase delta/epsilon-mediated excision repair in response to gamma radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

p53 Protein exhibits 3'-to-5' exonuclease activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

p53-catalyzed annealing of complementary single-stranded nucleic acids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

The dihedral symmetry of the p53 tetramerization domain mandates a conformational switch upon DNA binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203809

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203809

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Dimensions Publication ID

2 September 2017

1021946906

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1 reference