(Q38301976)

English

Early administration of the glucose-dependent insulinotropic polypeptide receptor antagonist (Pro3)GIP prevents the development of diabetes and related metabolic abnormalities associated with genetically inherited obesity in ob/ob mice.

scientific article published on 08 May 2007

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Early administration of the glucose-dependent insulinotropic polypeptide receptor antagonist (Pro3)GIP prevents the development of diabetes and related metabolic abnormalities associated with genetically inherited obesity in ob/ob mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Finbarr O'Harte

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Victor A. Gault

4

1 reference

Europe PubMed Central

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30 December 2019

6

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Europe PubMed Central

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30 December 2019

author name string

P L McClean

2

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Europe PubMed Central

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30 December 2019

P Harriott

5

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Europe PubMed Central

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30 December 2019

publication date

8 May 2007

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

50

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1532-1540

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Effects of the novel (Pro3)GIP antagonist and exendin(9-39)amide on GIP- and GLP-1-induced cyclic AMP generation, insulin secretion and postprandial insulin release in obese diabetic (ob/ob) mice: evidence that GIP is the major physiological increti

1 reference

https://api.crossref.org/works/10.1007%2FS00125-007-0692-2

21 January 2018

Elevated Post-Prandial Gastric Inhibitory Polypeptide Concentrations in Hypertriglyceridaemic Subjects

1 reference

https://api.crossref.org/works/10.1007%2FS00125-007-0692-2

21 January 2018

Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

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Therapeutic approaches to preserve islet mass in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

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Immunoreactive gastric inhibitory polypeptide and K cell hyperplasia in obese hyperglycaemic (ob/ob) mice fed high fat and high carbohydrate cafeteria diets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

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Hormonal changes after Roux-en Y gastric bypass for morbid obesity and the control of type-II diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

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Plasma immunoreactive gastric inhibitory polypeptide in obese hyperglycaemic (ob/ob) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

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Glucose-dependent insulinotropic polypeptide analogues and their therapeutic potential for the treatment of obesity-diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preparation of highly active enterogastrone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of GIP in spontaneous syndromes of obesity and diabetes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cellular and metabolic effects of a novel enzyme-resistant antagonist of glucose-dependent insulinotropic polypeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of short-term chemical ablation of the GIP receptor on insulin secretion, islet morphology and glucose homeostasis in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulation and degradation of GIP and GLP-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The entero-insular axis in type 2 diabetes--incretins as therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Restoration of normal glucose tolerance in severely obese patients after bilio-pancreatic diversion: role of insulin sensitivity and beta cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the physiology of GIP and GLP-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancing Incretin Action for the Treatment of Type 2 Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the entero-pancreatic hormones, gastric inhibitory polypeptide and glucagon-like polypeptide-1(7-36) amide, on fatty acid synthesis in explants of rat adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Ingestion of Triglyceride or Galactose on Secretion of Gastric Inhibitory Polypeptide and on Responses to Intravenous Glucose in Normal and Diabetic Subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of glucagon-like peptide-1(7-36)amide on motility and sensation of the proximal stomach in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric inhibitory polypeptide (GIP) and insulin in obesity: Increased response to stimulation and defective feedback control of serum levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GIP biology and fat metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiology and pathophysiology of GIP

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical ablation of gastric inhibitory polypeptide receptor action by daily (Pro3)GIP administration improves glucose tolerance and ameliorates insulin resistance and abnormalities of islet structure in obesity-related diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structurally modified analogues of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) as future antidiabetic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced hepatic insulin extraction in response to gastric inhibitory polypeptide compensates for reduced insulin secretion in normal-weight and normal glucose tolerant first-degree relatives of type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of genetic background and age on the expression of the obese hyperglycaemic syndrome in Aston ob/ob mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastric inhibitory polypeptide and effects of glycation on glucose transport and metabolism in isolated mouse abdominal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal plasma glucose and insulin responses in heterozygous lean (ob/+) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The key role of islet dysfunction in type II diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigations into the actions of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide on lipoprotein lipase activity in explants of rat adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-dependent insulinotropic polypeptide (GIP): anti-diabetic and anti-obesity potential?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17486314

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-007-0692-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486314%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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