Address
:
[go:
up one dir
,
main page
]
Include Form
Remove Scripts
Accept Cookies
Show Images
Show Referer
Rotate13
Base64
Strip Meta
Strip Title
Session Cookies
Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q38359705)
Watch
English
Hedgehog signaling in cancer stem cells: a focus on hematological cancers.
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
review article
1 reference
stated in
Europe PubMed Central
title
Hedgehog signaling in cancer stem cells: a focus on hematological cancers
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
main subject
neoplastic stem cells
1 reference
based on heuristic
inferred from title
author
Mhairi Copland
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
Victoria Campbell
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
publication date
16 January 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
published in
Stem Cells and Cloning: advances and applications
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
27-38
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
copyright license
Creative Commons Attribution-NonCommercial 3.0 Unported
start time
1 January 2015
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
0 references
cites work
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Somatic mutations of calreticulin in myeloproliferative neoplasms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Characterization of the TGF-β1 signaling abnormalities in the Gata1low mouse model of myelofibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The role of mutations in epigenetic regulators in myeloid malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hematopoietic stem cell heterogeneity takes center stage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Targeting the hedgehog pathway: role in cancer and clinical implications of its inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Palmitoylation of Hedgehog proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Targeting hedgehog in hematologic malignancy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
A crucial requirement for Hedgehog signaling in small cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The cancer stem cell: premises, promises and challenges
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Cancer stem cells: problems for therapy?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Small-molecule modulators of the Sonic Hedgehog signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
T-cell lymphoblastic lymphoma and T-cell acute lymphoblastic leukemia: a separate entity?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Paracrine Hedgehog signaling in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog signaling is dispensable for adult hematopoietic stem cell function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog signalling: emerging evidence for non-canonical pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Leukemia stem cells and human acute lymphoblastic leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Stem cell concepts renew cancer research
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The Gli code: an information nexus regulating cell fate, stemness and cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Patched1 regulates hedgehog signaling at the primary cilium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Essential role of stromally induced hedgehog signaling in B-cell malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Orchestrating ontogenesis: variations on a theme by sonic hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Prospective identification of tumorigenic prostate cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Cancer stem cells: lessons from leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Clinical resistance to imatinib: mechanisms and implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Distinct roles of PTCH2 splice variants in Hedgehog signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Identification of a cancer stem cell in human brain tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Small molecule modulation of Smoothened activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Patched acts catalytically to suppress the activity of Smoothened
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Hedgehog signaling in animal development: paradigms and principles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Stem cells, cancer, and cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
The molecular biology of chronic myeloid leukemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Development of the hematopoietic system in the mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Characterization of two patched receptors for the vertebrate hedgehog protein family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Activating Smoothened mutations in sporadic basal-cell carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Sertoli cell signaling by Desert hedgehog regulates the male germline
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Autoproteolysis in hedgehog protein biogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Mutations affecting segment number and polarity in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Charles F. Kettering Prize. P-glycoprotein and resistance to anticancer drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Effects of the hedgehog inhibitor GDC-0449, alone or in combination with dasatinib, on BCR-ABL-positive leukemia cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Novel therapy for therapy-resistant mantle cell lymphoma: multipronged approach with targeting of hedgehog signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
6 September 2017
Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Indian hedgehog supports definitive erythropoiesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Targeting of sonic hedgehog-GLI signaling: a potential strategy to improve therapy for mantle cell lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Hedgehog signalling in medulloblastoma, glioblastoma and neuroblastoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
A small-molecule antagonist of the hedgehog signaling pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
14 September 2017
Stromal cells expressing hedgehog-interacting protein regulate the proliferation of myeloid neoplasms.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
23 June 2018
Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: modification of the core skeleton for improved solubility
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
23 June 2018
Adenoviral vector-mediated transfer of the Indian hedgehog gene modulates lymphomyelopoiesis in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
23 June 2018
Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
23 June 2018
Bcl-2 family proteins: strategies for overcoming chemoresistance in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
23 June 2018
Cancer stem cell definitions and terminology: the devil is in the details.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Pharmacokinetic–Pharmacodynamic Analysis of Vismodegib in Preclinical Models of Mutational and Ligand-Dependent Hedgehog Pathway Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Heterogeneity of familial medulloblastoma and contribution of germline PTCH1 and SUFU mutations to sporadic medulloblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Turning off the switch in medulloblastoma: the inhibitory acetylation of an oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Hedgehog signaling pathway is activated in diffuse large B-cell lymphoma and contributes to tumor cell survival and proliferation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Bcl2 phosphorylation and active PKC alpha are associated with poor survival in AML.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Hedgehog signaling controls thymocyte progenitor homeostasis and differentiation in the thymus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-beta2m-/- repopulating cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Medulloblastoma growth inhibition by hedgehog pathway blockade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Teratogen-mediated inhibition of target tissue response to Shh signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
The product of hedgehog autoproteolytic cleavage active in local and long-range signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4325629
retrieved
31 August 2018
Patterned carbon nanotube growth using an electron beam sensitive direct writable catalyst
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25691811
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cancer stem cells: an evolving concept
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25691811
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25691811
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differential expression of Sonic hedgehog and Gli1 in hematological malignancies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25691811
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2147/SCCAA.S58613
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
4325629
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
25691811
1 reference
stated in
Europe PubMed Central
PMC publication ID
4325629
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25691811%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit