(Q38299277)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes (English)

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9 November 2019

0 references

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9 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

C Y Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

S Krauss

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

O Peroni

1 reference

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9 November 2019

D Grujic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

T Hagen

1 reference

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9 November 2019

O Boss

1 reference

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9 November 2019

Y B Kim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

X X Zheng

1 reference

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9 November 2019

B B Lowell

1 reference

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9 November 2019

language of work or name

English

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publication date

1 June 2001

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9 November 2019

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9 November 2019

volume

105

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9 November 2019

issue

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9 November 2019

page(s)

745-755

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Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter

9 November 2019

cites work

1 reference

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7 January 2021

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

1 reference

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7 January 2021

ATP-sensitive K+ channels and insulin secretion: their role in health and disease.

1 reference

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7 January 2021

Blood Glucose and Serum Insulin Levels in Lean and Genetically Obese Mice

1 reference

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7 January 2021

Effects of lipid on basal carbohydrate metabolism in normal men

1 reference

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7 January 2021

Effects of fat on insulin-stimulated carbohydrate metabolism in normal men

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

1 reference

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7 January 2021

Marked improvement of glucose homeostasis in diabetic ob/ob mice given oral vanadate.

1 reference

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7 January 2021

Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

1 reference

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7 January 2021

Effect of pertussis toxin on islet insulin secretion in obese (fa/fa) Zucker rats

1 reference

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7 January 2021

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

1 reference

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7 January 2021

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLP) and electrophoretic assays for the mouse obese (Lepob) mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Lipids up-regulate uncoupling protein 2 expression in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

1 reference

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7 January 2021

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Pancreatic islets in mice with the obese-hyperglycemic syndrome: lack of effect of carbutamide

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

The distribution pattern of the pancreatic islet volume in normal and hyperglycaemic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Brown adipose tissue thermogenesis and obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Recombinant human uncoupling protein-3 increases thermogenesis in yeast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Transport function and regulation of mitochondrial uncoupling proteins 2 and 3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

The importance of the beta-cell in the pathogenesis of type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Structure and function of the uncoupling protein from brown adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

An integrated view of beta-cell dysfunction in type-II diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Dietary fatty acids Up-regulate the expression of UCP2 in 3T3-L1 preadipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Retinoids activate proton transport by the uncoupling proteins UCP1 and UCP2.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Luminometric assays of ATP, phosphocreatine, and creatine for estimation of free ADP and free AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Cellular mechanisms of insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Uncoupling: new approaches to an old problem of bioenergetics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene

1 reference

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7 January 2021

Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Energy metabolism in uncoupling protein 3 gene knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

Renal metabolism of C-peptide in man

1 reference

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7 January 2021

Assessment of uncoupling activity of uncoupling protein 3 using a yeast heterologous expression system

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900378-6

7 January 2021

10.1016/S0092-8674(01)00378-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11440717%20AND%20SRC:MED&resulttype=core&format=json