(Q38010956)

26 August 2017

title

Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology (English)

1 reference

26 August 2017

0 references

1 reference

Bradley T Hyman

1 reference

26 August 2017

Junying Yuan

1 reference

26 August 2017

language of work or name

English

0 references

publication date

18 May 2012

1 reference

Nature Reviews Neuroscience

26 August 2017

published in

1 reference

26 August 2017

1 reference

26 August 2017

1 reference

26 August 2017

page(s)

395-406

1 reference

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

26 August 2017

cites work

1 reference

Apoptosis in the nervous system

31 March 2020

1 reference

Prevention of vertebrate neuronal death by the crmA gene

31 March 2020

1 reference

Cell death: critical control points

31 March 2020

1 reference

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

31 March 2020

1 reference

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

31 March 2020

1 reference

The Jekyll and Hyde functions of caspases

31 March 2020

1 reference

31 March 2020

1 reference

RAIDD is a new 'death' adaptor molecule

31 March 2020

1 reference

Caspase-containing complexes in the regulation of cell death and inflammation

31 March 2020

1 reference

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

31 March 2020

1 reference

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

31 March 2020

1 reference

bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death

31 March 2020

1 reference

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

31 March 2020

1 reference

A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w

31 March 2020

1 reference

BAX is required for neuronal death after trophic factor deprivation and during development

31 March 2020

1 reference

Evidence for the spontaneous production but massive programmed cell death of new neurons in the subcallosal zone of the postnatal mouse brain

31 March 2020

1 reference

BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

31 March 2020

1 reference

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

31 March 2020

1 reference

Mitogenic signaling from apoptotic cells in Drosophila.

31 March 2020

1 reference

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

31 March 2020

1 reference

Differential requirement for caspase 9 in apoptotic pathways in vivo.

31 March 2020

1 reference

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

31 March 2020

1 reference

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

31 March 2020

1 reference

Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia

31 March 2020

1 reference

Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.

31 March 2020

1 reference

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

31 March 2020

1 reference

Embryonic neuronal death due to neurotrophin and neurotransmitter deprivation occurs independent of Apaf-1.

31 March 2020

1 reference

Necroptosis as an alternative form of programmed cell death

31 March 2020

1 reference

Molecular mechanisms of necroptosis: an ordered cellular explosion

31 March 2020

1 reference

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

31 March 2020

1 reference

Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning

31 March 2020

1 reference

Local caspase activity directs engulfment of dendrites during pruning.

31 March 2020

1 reference

Neuronal remodeling and apoptosis require VCP-dependent degradation of the apoptosis inhibitor DIAP1

31 March 2020

1 reference

Dynamic role of postsynaptic caspase-3 and BIRC4 in zebra finch song-response habituation

31 March 2020

1 reference

Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb.

31 March 2020

1 reference

Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity

31 March 2020

1 reference

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

31 March 2020

1 reference

Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission.

31 March 2020

1 reference

XIAP as a ubiquitin ligase in cellular signaling

31 March 2020

1 reference

Regulation of apoptosis by XIAP ubiquitin-ligase activity

31 March 2020

1 reference

Autophosphorylated CaMKIIalpha acts as a scaffold to recruit proteasomes to dendritic spines

31 March 2020

1 reference

Protein degradation by the proteasome is required for synaptic tagging and the heterosynaptic stabilization of hippocampal late-phase long-term potentiation.

31 March 2020

1 reference

A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing

31 March 2020

1 reference

Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke

31 March 2020

1 reference

Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing

31 March 2020

1 reference

Function of BID -- a molecule of the bcl-2 family -- in ischemic cell death in the brain

31 March 2020

1 reference

BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

31 March 2020

1 reference

Neuroprotective strategies targeting apoptotic and necrotic cell death for stroke

31 March 2020

1 reference

Specific caspase pathways are activated in the two stages of cerebral infarction.

31 March 2020

1 reference

Caspase inhibitors reduce neuronal injury after focal but not global cerebral ischemia in rats

31 March 2020

1 reference

Reperfusion differentially induces caspase-3 activation in ischemic core and penumbra after stroke in immature brain

31 March 2020

1 reference

Cleaved caspase-3 expression after experimental stroke exhibits different phenotypes and is predominantly non-apoptotic

31 March 2020

1 reference

Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis

31 March 2020

1 reference

Caspase-3 cleaved spectrin colocalizes with neurofilament-immunoreactive neurons in Alzheimer's disease

31 March 2020

1 reference

The role of caspase cleavage of tau in Alzheimer disease neuropathology

31 March 2020

1 reference

Caspase-mediated degeneration in Alzheimer's disease

31 March 2020

1 reference

Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect?

31 March 2020

1 reference

Caspase activation in the limbic cortex of subjects with early Alzheimer's disease

31 March 2020

1 reference

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

31 March 2020

1 reference

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

31 March 2020

1 reference

Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain

31 March 2020

1 reference

Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease

31 March 2020

1 reference

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

31 March 2020

1 reference

Aβ Oligomers Cause Localized Ca2+Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

31 March 2020

1 reference

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

31 March 2020

1 reference

Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels

31 March 2020

1 reference

Neurodegeneration in Alzheimer's disease: caspases and synaptic element interdependence

31 March 2020

1 reference

Caspase activation precedes and leads to tangles

31 March 2020

1 reference

Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy

31 March 2020

1 reference

Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation

31 March 2020

1 reference

Activation of caspase-6 in aging and mild cognitive impairment

31 March 2020

1 reference

Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

31 March 2020

1 reference

Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease

31 March 2020

1 reference

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

31 March 2020

1 reference

Caspase activation without apoptosis: insight into Aβ initiation of neurodegeneration

31 March 2020

1 reference

Amyloid β-Mediated Cell Death of Cultured Hippocampal Neurons Reveals Extensive Tau Fragmentation without Increased Full-length Tau Phosphorylation

31 March 2020

1 reference

Convergence of amyloid-beta and tau pathologies on mitochondria in vivo

31 March 2020

1 reference

Microglia activation mediates fibrillar amyloid-β toxicity in the aged primate cortex.

31 March 2020

1 reference

Alzheimer's dementia begins as a disease of small blood vessels, damaged by oxidative‐induced inflammation and dysregulated amyloid metabolism: implications for early detection and therapy

31 March 2020

1 reference

In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.

31 March 2020

1 reference

Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease

31 March 2020

1 reference

Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

31 March 2020

1 reference

Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease

31 March 2020

1 reference

Tau suppression in a neurodegenerative mouse model improves memory function

31 March 2020

1 reference

Neuronal caspase-3 signaling: not only cell death

31 March 2020

1 reference

Synaptic and neuritic alterations during the progression of Alzheimer's disease

31 March 2020

1 reference

Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

31 March 2020

1 reference

DNA damage and activated caspase-3 expression in neurons and astrocytes: evidence for apoptosis in frontotemporal dementia

31 March 2020

1 reference

Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons.

31 March 2020

1 reference

Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models

31 March 2020

1 reference

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

31 March 2020

1 reference

Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1

31 March 2020

1 reference

Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure.

31 March 2020

1 reference

Caspase levels and execution efficiencies determine the apoptotic potential of the cell

31 March 2020

1 reference

For synapses, it's depression not death

31 March 2020

1 reference

Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22595785

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22595785

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Caspase-cleaved TAR DNA-binding protein-43 in Pick's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22595785

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRN3228

1 reference

Dimensions Publication ID

26 August 2017

1033822251

0 references

1 reference