(Q38078461)

28 August 2017

1 reference

title

Pichia pastoris: protein production host and model organism for biomedical research (English)

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28 August 2017

Pichia pastoris

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1 reference

Brigitte Gasser

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28 August 2017

Roland Prielhofer

1 reference

28 August 2017

Hans Marx

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28 August 2017

Michael Maurer

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28 August 2017

Justyna Nocon

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28 August 2017

Matthias Steiger

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28 August 2017

Verena Puxbaum

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28 August 2017

Michael Sauer

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28 August 2017

Diethard Mattanovich

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28 August 2017

language of work or name

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1 February 2013

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28 August 2017

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inferred from page(s)

published in

Future Microbiology

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28 August 2017

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28 August 2017

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28 August 2017

page(s)

191-208

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Heterologous protein production using the Pichia pastoris expression system.

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The yeast Golgi apparatus: insights and mysteries

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Peroxisome assembly: matrix and membrane protein biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Genome sequence of the recombinant protein production host Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Genome, secretome and glucose transport highlight unique features of the protein production host Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

High-quality genome sequence of Pichia pastoris CBS7435

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Posttransformational vector amplification in the yeast Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Directed gene copy number amplification in Pichia pastoris by vector integration into the ribosomal DNA locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Heterologous protein expression in the methylotrophic yeast Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

A strong nitrogen source-regulated promoter for controlled expression of foreign genes in the yeast Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Expression of the lacZ gene from two methanol-regulated promoters in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The ICL1 gene of Pichia pastoris, transcriptional regulation and use of its promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Phosphate-responsive promoter of a Pichia pastoris sodium phosphate symporter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Promoter library designed for fine-tuned gene expression in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Identification and characterisation of novel Pichia pastoris promoters for heterologous protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Versatile modeling and optimization of fed batch processes for the production of secreted heterologous proteins with Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

GAP Promoter Library for Fine-Tuning of Gene Expression in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Translation elongation factor 1-alpha gene from Pichia pastoris: molecular cloning, sequence, and use of its promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Engineering of biotin-prototrophy in Pichia pastoris for robust production processes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Genome-scale analysis of library sorting (GALibSo): Isolation of secretion enhancing factors for recombinant protein production in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Operational strategies, monitoring and control of heterologous protein production in the methylotrophic yeast Pichia pastoris under different promoters: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

SCPD: a promoter database of the yeast Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Protein secretion in Pichia pastoris and advances in protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Enhancement of protein secretion in Pichia pastoris by overexpression of protein disulfide isomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Expression of heterologous proteins in Pichia pastoris: a useful experimental tool in protein engineering and production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Protein quality control in the early secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Protein folding and modification in the mammalian endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Oxidative protein folding in the secretory pathway and redox signaling across compartments and cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Mechanism and components of endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The endoplasmic reticulum and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

One step at a time: endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Engineering of protein secretion in yeast: strategies and impact on protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Cooverexpression of chaperones for enhanced secretion of a single-chain antibody fragment in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Engineering of Pichia pastoris for improved production of antibody fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Engineering of a Pichia pastoris expression system for secretion of high amounts of intact human parathyroid hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Co-expression of human protein disulfide isomerase (hPDI) enhances secretion of bovine follicle-stimulating hormone (bFSH) in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Overproduction of Pichia pastoris or Plasmodium falciparum protein disulfide isomerase affects expression, folding and O-linked glycosylation of a malaria vaccine candidate expressed in P. pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Cloning, disruption and protein secretory phenotype of the GAS1 homologue of Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Molecular genetic manipulation of Pichia pastoris SEC4 governs cell growth and glucoamylase secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Modeling and measuring intracellular fluxes of secreted recombinant protein in Pichia pastoris with a novel 34S labeling procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Systematic single-cell analysis of Pichia pastoris reveals secretory capacity limits productivity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Enhanced secretion of heterologous proteins in Pichia pastoris following overexpression of Saccharomyces cerevisiae chaperone proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Glycosylation engineering in yeast: the advent of fully humanized yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Engineering of glycosylation in yeast and other fungi: current state and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Recent patents on the Pichia pastoris expression system: expanding the toolbox for recombinant protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Expression of recombinant proteins in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Yeast systems biotechnology for the production of heterologous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Novel insights into the unfolded protein response using Pichia pastoris specific DNA microarrays.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The response to unfolded protein is involved in osmotolerance of Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

A multi-level study of recombinant Pichia pastoris in different oxygen conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The impact of oxygen on the transcriptome of recombinant S. cerevisiae and P. pastoris - a comparative analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

The effect of temperature on the proteome of recombinant Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Physiological response of Pichia pastoris GS115 to methanol-induced high level production of the Hepatitis B surface antigen: catabolic adaptation, stress responses, and autophagic processes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

A proteomic analysis of the Pichia pastoris secretome in methanol-induced cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Tracing putative trafficking of the glycolytic enzyme enolase via SNARE-driven unconventional secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Systems metabolic engineering: genome-scale models and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Genome-scale metabolic model of methylotrophic yeast Pichia pastoris and its use for in silico analysis of heterologous protein production.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Genome-scale metabolic reconstruction and in silico analysis of methylotrophic yeast Pichia pastoris for strain improvement

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Quantitative physiology of Pichia pastoris during glucose-limited high-cell density fed-batch cultivation for recombinant protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Metabolic flux profiling of recombinant protein secreting Pichia pastoris growing on glucose:methanol mixtures.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

High-Throughput Protein Expression Using a Combination of Ligation-Independent Cloning (LIC) and Infrared Fluorescent Protein (IFP) Detection

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Efficient vectors for expression cloning of large numbers of PCR fragments in P. pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

High-throughput construction of expression system using yeast Pichia pastoris, and its application to membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

High-throughput screening for expression of heterologous proteins in the yeast Pichia pastoris.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Reliable high-throughput screening with Pichia pastoris by limiting yeast cell death phenomena

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Generation and screening of Pichia pastoris strains with enhanced protein production by use of microengraving

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Sequence-based factors influencing the expression of heterologous genes in the yeast Pichia pastoris--A comparative view on 79 human genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Identification of pexophagy genes by restriction enzyme-mediated integration

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

A combinatorial genetic library approach to target heterologous glycosylation enzymes to the endoplasmic reticulum or the Golgi apparatus of Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Recent developments in yeast cell surface display toward extended applications in biotechnology.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Applications of cell sorting in biotechnology

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Novel yeast bioassay for high-throughput screening of matrix metalloproteinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

A new screening method based on yeast-expressed human dipeptidyl peptidase IV and discovery of novel inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Pexophagy: the selective degradation of peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Development of the yeast Pichia pastoris as a model organism for a genetic and molecular analysis of peroxisome assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Pexophagy: the selective autophagy of peroxisomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Golgi structure correlates with transitional endoplasmic reticulum organization in Pichia pastoris and Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Tomographic evidence for continuous turnover of Golgi cisternae in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Membrane traffic within the Golgi apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Sec12 binds to Sec16 at transitional ER sites

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Oxidative protein folding and unfolded protein response elicit differing redox regulation in endoplasmic reticulum and cytosol of yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

21 January 2018

ER stress and diseases.

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

ER and aging-Protein folding and the ER stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Effect of copper and manganese on the de novo generation of protease-resistant prion protein in yeast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

From laboratory to Phase I/II cancer trials with recombinant biotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Recombinant protein vaccines against the asexual blood stages of Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Secretory expression of interferon-alpha 2b in recombinant Pichia pastoris using three different secretion signals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

High-level expression, purification and characterization of recombinant Aspergillus oryzae alkaline protease in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Acidophilic xylanase from Aureobasidium pullulans: efficient expression and secretion in Pichia pastoris and mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Hydrophobin signal sequence mediates efficient secretion of recombinant proteins in Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Viral preprotoxin signal sequence allows efficient secretion of green fluorescent protein by Candida glabrata, Pichia pastoris, Saccharomyces cerevisiae, and Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Isolation of Pichia pastoris PIR genes and their utilization for cell surface display and recombinant protein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

A quantitative analysis of the benefits of mixed feeds of sorbitol and methanol for the production of recombinant avidin with Pichia pastoris

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Developing high cell density fed-batch cultivation strategies for heterologous protein production in Pichia pastoris using the nitrogen source-regulated FLD1 Promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Macromolecular and elemental composition analysis and extracellular metabolite balances of Pichia pastoris growing at different oxygen levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Monitoring intracellular redox conditions in the endoplasmic reticulum of living yeasts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Catabolite repression of Aox in Pichia pastoris is dependent on hexose transporter PpHxt1 and pexophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Highly efficient gene targeting in the Aspergillus niger kusA mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Engineering Aggregation Resistance in IgG by Two Independent Mechanisms: Lessons from Comparison of Pichia pastoris and Mammalian Cell Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

Golgi maturation visualized in living yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFMB.12.133

21 January 2018

Identifiers

DOI

10.2217/FMB.12.133

1 reference

28 August 2017

1 reference