(Q37815130)

23 August 2017

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title

Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues (English)

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23 August 2017

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Christopher D Gregory

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John D Pound

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23 August 2017

publication date

25 October 2010

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23 August 2017

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23 August 2017

volume

223

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23 August 2017

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23 August 2017

page(s)

177-194

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Nineteenth century research on naturally occurring cell death and related phenomena

23 August 2017

cites work

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Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

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A blast from the past: clearance of apoptotic cells regulates immune responses.

21 January 2018

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Clearance of apoptotic cells: getting rid of the corpses.

21 January 2018

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Apoptotic cell removal in development and tissue homeostasis

21 January 2018

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Engulfment of apoptotic cells: signals for a good meal

21 January 2018

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Clearance of apoptotic cells: implications in health and disease

21 January 2018

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Microenvironmental influences of apoptosis in vivo and in vitro

21 January 2018

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Postnatal changes in retinal ganglion cell and optic axon populations in the pigmented rat.

21 January 2018

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Cell death and control of cell survival in the oligodendrocyte lineage

21 January 2018

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Mechanisms and Functions of Cell Death

21 January 2018

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Clearance of apoptotic cells by phagocytes

21 January 2018

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Pentraxins, humoral innate immunity and tissue injury

21 January 2018

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Immunogenic and tolerogenic cell death

21 January 2018

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Autoimmunity and the clearance of dead cells

21 January 2018

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Inefficient clearance of dying cells in patients with SLE: anti-dsDNA autoantibodies, MFG-E8, HMGB-1 and other players.

21 January 2018

1 reference

Infection and apoptosis as a combined inflammatory trigger

21 January 2018

1 reference

Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway

21 January 2018

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Innate apoptotic immunity: the calming touch of death

21 January 2018

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Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

21 January 2018

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CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis

21 January 2018

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Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

21 January 2018

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Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a "come-and-get-me" signal

21 January 2018

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Apoptotic myocytes generate monocyte chemoattractant protein-1 and mediate macrophage recruitment

21 January 2018

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Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

21 January 2018

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Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte

21 January 2018

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Human CD14 mediates recognition and phagocytosis of apoptotic cells

21 January 2018

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Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis

21 January 2018

1 reference

BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module

21 January 2018

1 reference

Identification of Tim4 as a phosphatidylserine receptor

21 January 2018

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Rapid cell corpse clearance by stabilin-2, a membrane phosphatidylserine receptor

21 January 2018

1 reference

Immunobiology of the TAM receptors

21 January 2018

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Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

21 January 2018

1 reference

A model to die for: signaling to apoptotic cell removal in worm, fly and mouse

21 January 2018

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Innate immune discrimination of apoptotic cells: repression of proinflammatory macrophage transcription is coupled directly to specific recognition

21 January 2018

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Apoptotic volume decrease and the incredible shrinking cell

21 January 2018

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

21 January 2018

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Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

21 January 2018

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Rho kinase regulates fragmentation and phagocytosis of apoptotic cells

21 January 2018

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A short history of blebbing

21 January 2018

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Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

21 January 2018

1 reference

Membrane microparticles: two sides of the coin

21 January 2018

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Exosomes--vesicular carriers for intercellular communication

21 January 2018

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Tumour-released exosomes and their implications in cancer immunity.

21 January 2018

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Membrane microvesicles as actors in the establishment of a favorable prostatic tumoral niche: a role for activated fibroblasts and CX3CL1-CX3CR1 axis

21 January 2018

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Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A.

21 January 2018

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Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells

21 January 2018

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Apoptotic cells with oxidation-specific epitopes are immunogenic and proinflammatory

21 January 2018

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ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors.

21 January 2018

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Cell biology: Sent by the scent of death

21 January 2018

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Inhibition of eosinophil migration by lactoferrin

21 January 2018

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Lactoferrin down-regulates the LPS-induced cytokine production in monocytic cells via NF-kappa B.

21 January 2018

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Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses

21 January 2018

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I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation

21 January 2018

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Extracellular ATP induces a large nonselective conductance in macrophage plasma membranes

21 January 2018

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The P2Y11 receptor mediates the ATP-induced maturation of human monocyte-derived dendritic cells

21 January 2018

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Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage.

21 January 2018

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Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

21 January 2018

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Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases

21 January 2018

1 reference

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

21 January 2018

1 reference

Exposure of anionic phospholipids serves as anti-inflammatory and immunosuppressive signal--implications for antiphospholipid syndrome and systemic lupus erythematosus.

21 January 2018

1 reference

Specific recognition of apoptotic cells reveals a ubiquitous and unconventional innate immunity

21 January 2018

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Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

21 January 2018

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Transcriptional suppression of interleukin-12 gene expression following phagocytosis of apoptotic cells

21 January 2018

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Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1.

21 January 2018

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Transcriptional and translational regulation of TGF-beta production in response to apoptotic cells

21 January 2018

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Inhibitory effects of apoptotic cell ingestion upon endotoxin-driven myeloid dendritic cell maturation.

21 January 2018

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Apoptotic cells, at all stages of the death process, trigger characteristic signaling events that are divergent from and dominant over those triggered by necrotic cells: Implications for the delayed clearance model of autoimmunity

21 January 2018

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Cell surface externalization of annexin A1 as a failsafe mechanism preventing inflammatory responses during secondary necrosis.

21 January 2018

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Annexin 1: more than an anti-phospholipase protein

21 January 2018

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Phagocytosis of opsonized apoptotic cells: roles for 'old-fashioned' receptors for antibody and complement

21 January 2018

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The immunogenicity of tumor cell death

21 January 2018

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Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis

21 January 2018

1 reference

Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation

21 January 2018

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Production and neuroprotective functions of fractalkine in the central nervous system

21 January 2018

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Control of microglial neurotoxicity by the fractalkine receptor

21 January 2018

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Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

21 January 2018

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Alveolar macrophages that phagocytose apoptotic neutrophils produce hepatocyte growth factor during bacterial pneumonia in mice

21 January 2018

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Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro

21 January 2018

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Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling

21 January 2018

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Apoptotic cells initiate endothelial cell sprouting via electrostatic signaling

21 January 2018

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Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila.

21 January 2018

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Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role

21 January 2018

1 reference

Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila

21 January 2018

1 reference

The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc.

21 January 2018

1 reference

Caspases in cell survival, proliferation and differentiation.

21 January 2018

1 reference

Nonapoptotic functions of caspases: caspases as regulatory molecules for immunity and cell-fate determination

21 January 2018

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Can't live without them, can live with them: roles of caspases during vital cellular processes

21 January 2018

1 reference

Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye.

21 January 2018

1 reference

The polarization of immune cells in the tumour environment by TGFbeta

21 January 2018

1 reference

Multifunctional roles of lactoferrin: a critical overview

21 January 2018

1 reference

Non-apoptotic functions of caspases in cellular proliferation and differentiation

21 January 2018

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Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview

21 January 2018

1 reference

Macrophage polarization comes of age.

21 January 2018

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Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

21 January 2018

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Macrophage polarization in tumour progression

21 January 2018

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Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate.

21 January 2018

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Tumor cell apoptosis polarizes macrophages role of sphingosine-1-phosphate.

21 January 2018

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Apoptotic cell-derived sphingosine-1-phosphate promotes HuR-dependent cyclooxygenase-2 mRNA stabilization and protein expression

21 January 2018

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The supernatant of apoptotic cells causes transcriptional activation of hypoxia-inducible factor-1alpha in macrophages via sphingosine-1-phosphate and transforming growth factor-beta.

21 January 2018

1 reference

"Host tissue damage" signal ATP promotes non-directional migration and negatively regulates toll-like receptor signaling in human monocytes.

21 January 2018

1 reference

CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival

21 January 2018

1 reference

Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner.

21 January 2018

1 reference

Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN

21 January 2018

1 reference

Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice

21 January 2018

1 reference

Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo

21 January 2018

1 reference

Recognition of live phosphatidylserine-labeled tumor cells by dendritic cells: a novel approach to immunotherapy of skin cancer

21 January 2018

1 reference

Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy

21 January 2018

1 reference

Antiphosphatidylserine antibody combined with irradiation damages tumor blood vessels and induces tumor immunity in a rat model of glioblastoma

21 January 2018

1 reference

Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies

21 January 2018

1 reference

Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase

21 January 2018

1 reference

Clearance deficiency and systemic lupus erythematosus (SLE).

21 January 2018

1 reference

Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

21 January 2018

1 reference

Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice.

21 January 2018

1 reference

Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa.

21 January 2018

1 reference

Ulcerative colitis and autoimmunity induced by loss of myeloid alphav integrins

21 January 2018

1 reference

TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.

21 January 2018

1 reference

Cell death by necrosis: towards a molecular definition

21 January 2018

1 reference

The inflammatory response to cell death

21 January 2018

1 reference

Mincle is an ITAM-coupled activating receptor that senses damaged cells

21 January 2018

1 reference

Necrosis: C-type lectins sense cell death

21 January 2018

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Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.

21 January 2018

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Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype

21 January 2018

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A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo

21 January 2018

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Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8

21 January 2018

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Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice

21 January 2018

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

21 January 2018

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

21 January 2018

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C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction

21 January 2018

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Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

21 January 2018

1 reference

Host tissue damage by phagocytes

21 January 2018

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Dying neural cells activate glia through the release of a protease product.

21 January 2018

1 reference

Cytochrome c-induced lymphocyte death from the outside in: inhibition by serum leucine-rich alpha-2-glycoprotein-1.

21 January 2018

1 reference

Growth-inhibitory activity of lymphoid cell plasma membranes. II. Partial characterization of the inhibitor

21 January 2018

1 reference

Growth-inhibitory activity of lymphoid cell plasma membranes. I. Inhibition of lymphocyte and lymphoid tumor cell growth

21 January 2018

1 reference

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

21 January 2018

1 reference

Genetic Studies of the Relationship of Tumour–Host Cells: Effect of Tumour Cells killed by X-rays upon the Growth of Admixed Viable Cells

21 January 2018

1 reference

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

21 January 2018

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Immunosuppressive effects of apoptotic cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.2792

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23 August 2017

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