(Q37809577)

23 August 2017

title

Staying on message: design principles for controlling nonspecific responses to siRNA (English)

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

27 August 2024

0 references

Joshua N. Leonard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078117

27 August 2024

author name string

Shirley Samuel-Abraham

series ordinal

1 reference

23 August 2017

language of work or name

English

0 references

publication date

1 December 2010

1 reference

full work available at URL

23 August 2017

https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1742-4658.2010.07905.x

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21078117

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1742-4658.2010.07905.x

27 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1742-4658.2010.07905.x

27 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

27 August 2024

1 reference

23 August 2017

volume

277

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23 August 2017

1 reference

23 August 2017

page(s)

4828-4836

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Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

23 August 2017

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

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21 January 2018

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21 January 2018

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siRNA binding proteins of microglial cells: PKR is an unanticipated ligand.

21 January 2018

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21 January 2018

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Small self-RNA generated by RNase L amplifies antiviral innate immunity

21 January 2018

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2'-5'-Oligoadenylate synthetase is activated by a specific RNA sequence motif

21 January 2018

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Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

21 January 2018

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21 January 2018

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Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

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TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages

21 January 2018

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Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses

21 January 2018

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21 January 2018

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Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.

21 January 2018

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 January 2018

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

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5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

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Designing highly active siRNAs for therapeutic applications.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Positional effect of chemical modifications on short interference RNA activity in mammalian cells

21 January 2018

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Cleavage of the siRNA passenger strand during RISC assembly in human cells

21 January 2018

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Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

21 January 2018

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Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07905.X

siRNA function in RNAi: a chemical modification analysis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07905.X

The critical DNA flanking sequences of a CpG oligodeoxynucleotide, but not the 6 base CpG motif, can be replaced with RNA without quantitative or qualitative changes in Toll-like receptor 9-mediated activity

21 January 2018

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Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization

21 January 2018

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

21 January 2018

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Production of type I interferons: plasmacytoid dendritic cells and beyond

21 January 2018

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Toll-like receptor control of the adaptive immune responses

21 January 2018

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Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH.

21 January 2018

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07905.X

Misinterpreting the therapeutic effects of small interfering RNA caused by immune stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07905.X

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07905.X

Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

27 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

2'-O-methyl-modified RNAs act as TLR7 antagonists

27 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

27 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

A second binding site for double-stranded RNA in TLR3 and consequences for interferon activation

27 August 2024

1 reference

https://api.crossref.org/works/10.1111/J.1742-4658.2010.07905.X

27 August 2024

Identifiers

1 reference

23 August 2017

1 reference