(Q37807909)

23 August 2017

title

The "dying-back" phenomenon of motor neurons in ALS. (English)

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amyotrophic lateral sclerosis

23 August 2017

main subject

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Michal Dadon-Nachum

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23 August 2017

Eldad Melamed

series ordinal

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23 August 2017

Daniel Offen

series ordinal

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23 August 2017

publication date

7 November 2010

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Journal of Molecular Neuroscience

23 August 2017

published in

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23 August 2017

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23 August 2017

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23 August 2017

page(s)

470-477

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Semaphorin function in neural plasticity and disease.

23 August 2017

cites work

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12 December 2020

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

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12 December 2020

IGF-I specifically enhances axon outgrowth of corticospinal motor neurons

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12 December 2020

Pre-symptomatic detection of chronic motor deficits and genotype prediction in congenic B6.SOD1(G93A) ALS mouse model.

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BDNF heightens the sensitivity of motor neurons to excitotoxic insults through activation of TrkB.

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The bound leading the bound: target-derived receptors act as guidance cues

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Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

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A longitudinal study comparing thenar motor unit number estimates to other quantitative tests in patients with amyotrophic lateral sclerosis

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12 December 2020

Molecular and cellular pathways of neurodegeneration in motor neurone disease

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12 December 2020

Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases

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12 December 2020

Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice

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12 December 2020

Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

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12 December 2020

Axon guidance proteins: novel therapeutic targets for ALS?

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12 December 2020

Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway.

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12 December 2020

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

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12 December 2020

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

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12 December 2020

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

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12 December 2020

Amyotrophic lateral sclerosis: all roads lead to Rome

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12 December 2020

Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model

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12 December 2020

ALS: a disease of motor neurons and their nonneuronal neighbors

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12 December 2020

Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis

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12 December 2020

Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant

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12 December 2020

Clinical and molecular aspects of motoneurone diseases: animal models, neurotrophic factors and Bcl-2 oncoprotein

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12 December 2020

The resilience of the size principle in the organization of motor unit properties in normal and reinnervated adult skeletal muscles

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12 December 2020

Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration.

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12 December 2020

BDNF rescues myosin heavy chain IIB muscle fibers after neonatal nerve injury

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12 December 2020

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

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12 December 2020

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

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12 December 2020

Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

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12 December 2020

Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

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12 December 2020

Time course of preferential motor unit loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis

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12 December 2020

Presymptomatic biochemical changes in hindlimb muscle of G93A human Cu/Zn superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis

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12 December 2020

DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS.

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12 December 2020

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

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12 December 2020

Nogo expression in muscle correlates with amyotrophic lateral sclerosis severity

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12 December 2020

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

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12 December 2020

Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.

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12 December 2020

Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis

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12 December 2020

Intramuscular grafts of myoblasts genetically modified to secrete glial cell line-derived neurotrophic factor prevent motoneuron loss and disease progression in a mouse model of familial amyotrophic lateral sclerosis

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12 December 2020

Unraveling the mechanisms involved in motor neuron degeneration in ALS

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12 December 2020

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

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12 December 2020

VEGF at the neurovascular interface: therapeutic implications for motor neuron disease

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12 December 2020

Mutant Cu/Zn-superoxide dismutase associated with amyotrophic lateral sclerosis destabilizes vascular endothelial growth factor mRNA and downregulates its expression

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12 December 2020

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

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12 December 2020

Amplitude-dependent slowing of conduction in amyotrophic lateral sclerosis and polyneuropathy

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12 December 2020

Early abnormalities in transgenic mouse models of amyotrophic lateral sclerosis

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12 December 2020

Recovery from paralysis in adult rats using embryonic stem cells.

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12 December 2020

Insulin-like growth factor-I for the treatment of amyotrophic lateral sclerosis

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12 December 2020

Axon pathology in neurological disease: a neglected therapeutic target

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12 December 2020

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease

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12 December 2020

Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis

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12 December 2020

Increased survival and function of SOD1 mice after glial cell-derived neurotrophic factor gene therapy

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12 December 2020

Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.

1 reference

12 December 2020

VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice

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12 December 2020

10.1007/S12031-010-9467-1

Identifiers

DOI

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23 August 2017

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