(Q37759873)

22 August 2017

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title

Cognitive deficits and associated neurological complications in individuals with Down's syndrome (English)

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22 August 2017

Mara Dierssen

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Ira T Lott

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22 August 2017

publication date

1 June 2010

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22 August 2017

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22 August 2017

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22 August 2017

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22 August 2017

page(s)

623-633

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The four ages of Down syndrome

22 August 2017

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7 January 2021

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7 January 2021

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7 January 2021

The endophenotype concept in psychiatry: etymology and strategic intentions

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7 January 2021

Homocysteine metabolism in children with Down syndrome: in vitro modulation

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7 January 2021

Genetic determinants of folate and vitamin B12 metabolism: a common pathway in neural tube defect and Down syndrome?

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7 January 2021

Learning and memory as a function of age in Down syndrome: a study using animal-based tasks

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7 January 2021

Aneuploidy: from a physiological mechanism of variance to Down syndrome

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7 January 2021

Measuring behavior in genetic disorders of mental retardation

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Selective neuroanatomic abnormalities in Down's syndrome and their cognitive correlates: evidence from MRI morphometry.

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7 January 2021

Down's syndrome: a genetic disorder in biobehavioral perspective

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7 January 2021

Text comprehension in Down syndrome: the role of lower and higher level abilities

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7 January 2021

Verbal, visual, and spatio-sequential short-term memory: assessment of the storage capacities of children and teenagers with Down's syndrome.

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7 January 2021

A specific deficit in visuospatial simultaneous working memory in Down syndrome.

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7 January 2021

Working memory and cognitive skills in individuals with Down syndrome.

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7 January 2021

Working memory and Down syndrome

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7 January 2021

Patterns of syntactic development in children with Williams syndrome and Down's syndrome: evidence from passives and wh-questions.

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7 January 2021

A longitudinal study of motivation and competence in children with Down syndrome: early childhood to early adolescence

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7 January 2021

Magnetic resonance imaging analysis of age-related changes in the brains of individuals with Down's syndrome

1 reference

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7 January 2021

Long-term memory in mental retardation: evidence for a specific impairment in subjects with Down's syndrome.

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7 January 2021

Strengthening behavioral research on genetic mental retardation syndromes

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7 January 2021

Direct and Indirect Behavioral Effects of Different Genetic Disorders of Mental Retardation

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7 January 2021

The development of learning difficulties in children with Down's syndrome.

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7 January 2021

Implicit versus explicit memory function in children with Down and Williams syndrome.

1 reference

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7 January 2021

The effect of damage to the cerebellum on sensorimotor and cognitive function in children and adolescents.

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7 January 2021

Cerebellar contributions to cognition

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7 January 2021

The cerebellar cognitive affective syndrome

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7 January 2021

The hippocampus is required for short-term topographical memory in humans

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7 January 2021

On the cerebello-cerebral interactions

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7 January 2021

Cerebellum and nonmotor function

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7 January 2021

Executive function in adolescents with Down Syndrome.

1 reference

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7 January 2021

Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment

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7 January 2021

Dendritic anomalies in disorders associated with mental retardation

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7 January 2021

Amygdala and hippocampal volumes in children with Down syndrome: a high-resolution MRI study

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7 January 2021

Neuroanatomy of Down's syndrome: a high-resolution MRI study.

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7 January 2021

Tc-99m HMPAO brain perfusion imaging in young Down's syndrome patients

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7 January 2021

Microstructure of the neocortex: comparative aspects

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7 January 2021

Emotion recognition by children with Down syndrome: investigation of specific impairments and error patterns

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7 January 2021

Socio-cognitive understanding: a strength or weakness in Down's syndrome?

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7 January 2021

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

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7 January 2021

Murine models for Down syndrome

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7 January 2021

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome.

1 reference

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7 January 2021

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

1 reference

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7 January 2021

DYRK1A (dual-specificity tyrosine-phosphorylated and -regulated kinase 1A): a gene with dosage effect during development and neurogenesis.

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7 January 2021

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

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7 January 2021

1 reference

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7 January 2021

Using mouse models to explore genotype-phenotype relationship in Down syndrome.

1 reference

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7 January 2021

Seizure Disorders in Down Syndrome

1 reference

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7 January 2021

The long-term effects of neonatal seizures

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7 January 2021

Absence seizures: a review of recent reports with new concepts

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7 January 2021

Multi-institutional study on the correlation between chromosomal abnormalities and epilepsy

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7 January 2021

Antiepileptic drug-induced cognitive adverse effects: potential mechanisms and contributing factors

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7 January 2021

Adverse effects of phenytoin given for late-onset seizures in adults with Down syndrome

1 reference

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7 January 2021

Seizures in children with Down syndrome: etiology, characteristics and outcome

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7 January 2021

Epilepsy in childhood down syndrome

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7 January 2021

Increased levels of carbonic anhydrase II in the developing Down syndrome brain.

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7 January 2021

Infantile spasms in children with Down syndrome.

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7 January 2021

Seizure frequency and characteristics in children with Down syndrome

1 reference

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7 January 2021

Infantile spasms in Down syndrome--effects of delayed anticonvulsive treatment.

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7 January 2021

Developing an animal model for infantile spasms: pathogenesis, problems and progress

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7 January 2021

Clinical and EEG features of epilepsy in children and adolescents in Down syndrome

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7 January 2021

Down syndrome, Alzheimer's disease and seizures

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7 January 2021

Phenotype associated with APP duplication in five families

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7 January 2021

Epilepsy and cognitive impairments in Alzheimer disease

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7 January 2021

Use of electroencephalography to detect Alzheimer's disease in Down's syndrome.

1 reference

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7 January 2021

Early amyloid deposition in the medial temporal lobe of young Down syndrome patients: a regional quantitative analysis

1 reference

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7 January 2021

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

1 reference

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7 January 2021

Chromosome 21 and down syndrome: from genomics to pathophysiology

1 reference

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7 January 2021

ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.

1 reference

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7 January 2021

Drosophila melanogaster homolog of Down syndrome critical region 1 is critical for mitochondrial function

1 reference

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7 January 2021

Alzheimer's disease in Down syndrome: neurobiology and risk.

1 reference

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7 January 2021

Intrinsic defect of the immune system in children with Down syndrome: a review.

1 reference

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7 January 2021

DNA damage and repair: relevance to mechanisms of neurodegeneration

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7 January 2021

Role of DNA dynamics in Alzheimer's disease

1 reference

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7 January 2021

Dementia in people with Down's syndrome.

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7 January 2021

Dementia and mortality in persons with Down's syndrome

1 reference

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7 January 2021

Promising strategies for the prevention of dementia

1 reference

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7 January 2021

Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down syndrome

1 reference

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7 January 2021

Amyloid beta concentrations in older people with Down syndrome and dementia.

1 reference

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7 January 2021

Molecular dating of senile plaques in the brains of individuals with Down syndrome and in aged dogs

1 reference

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7 January 2021

A four year prospective study of age-related cognitive change in adults with Down's syndrome.

1 reference

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7 January 2021

Symptoms of dementia among adults with Down's syndrome: a qualitative study

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7 January 2021

Neurological changes and emotional functioning in adults with Down Syndrome

1 reference

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7 January 2021

Executive dysfunction and its association with personality and behaviour changes in the development of Alzheimer's disease in adults with Down syndrome and mild to moderate learning disabilities.

1 reference

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7 January 2021

Selective attention deficits associated with mild cognitive impairment and early stage Alzheimer's disease in adults with Down syndrome.

1 reference

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7 January 2021

Sequence of cognitive decline in dementia in adults with Down's syndrome.

1 reference

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7 January 2021

Diagnosing Alzheimer's dementia in Down syndrome: problems and possible solutions

1 reference

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7 January 2021

Obstructive sleep apnea: Should all children with Down syndrome be tested?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2810%2970112-5

7 January 2021

The effect of chronic or intermittent hypoxia on cognition in childhood: a review of the evidence

1 reference

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7 January 2021

Daytime sleepiness and hyperactivity in children with suspected sleep-disordered breathing

1 reference

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7 January 2021

Cognitive status in Down syndrome individuals with sleep disordered breathing deficits (SDB).

1 reference

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7 January 2021

Otitis media in a mouse model for Down syndrome

1 reference

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7 January 2021

Sensory impairments and health concerns related to the degree of intellectual disability in people with Down syndrome

1 reference

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7 January 2021

Inner ear dysplasia is common in children with Down syndrome (trisomy 21).

1 reference

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7 January 2021

Ophthalmic abnormalities in children with Down syndrome

1 reference

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7 January 2021

Surveillance of vision and ocular disorders in children with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2810%2970112-5

7 January 2021

Inter-hemispheric functional coupling of eyes-closed resting EEG rhythms in adolescents with Down syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2810%2970112-5

7 January 2021

Does visual impairment lead to additional disability in adults with intellectual disabilities?

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2810%2970112-5

7 January 2021

Evidence for a specific defect in hippocampal memory in overt and subclinical hypothyroidism.

1 reference

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7 January 2021

The association of congenital hypothyroidism and congenital gastrointestinal anomalies in Down's syndrome infants

1 reference

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7 January 2021

Lower neonatal screening thyroxine concentrations in down syndrome newborns

1 reference

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7 January 2021

Health supervision for children with Down syndrome

1 reference

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7 January 2021

Natural history of thyroid function in adults with Down syndrome--10-year follow-up study

1 reference

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7 January 2021

Increased incidence of extrathyroidal congenital malformations in Japanese patients with congenital hypothyroidism and their relationship with Down syndrome and other factors

1 reference

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7 January 2021

Current dilemmas in Down syndrome clinical care: celiac disease, thyroid disorders, and atlanto-axial instability

1 reference

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7 January 2021

Hashimoto encephalopathy and Down syndrome

1 reference

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7 January 2021

Psychiatric and behavioral disorders in persons with Down syndrome

1 reference

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7 January 2021

Prevalence of pervasive developmental disorder in Down's syndrome

1 reference

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7 January 2021

Differences in the clinical presentation of Trisomy 21 with and without autism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2810%2970112-5

7 January 2021

Down syndrome and comorbid autism-spectrum disorder: characterization using the aberrant behavior checklist.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2810%2970112-5

7 January 2021

Obsessional slowness in Down's syndrome

1 reference

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7 January 2021

Behaviour problems and adults with Down syndrome: childhood risk factors.

1 reference

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7 January 2021

Differential rates of psychiatric disorders in adults with Down's syndrome compared with other mentally handicapped adults

1 reference

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7 January 2021

Neurobehavioral disorders in children, adolescents, and young adults with Down syndrome

1 reference

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7 January 2021

Lipids and lipoproteins in persons with Down's syndrome

1 reference

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7 January 2021

Down's syndrome: an atheroma-free model?

1 reference

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7 January 2021

Does Down's syndrome support the homocysteine theory of atherogenesis? Experience in elderly subjects with trisomy 21.

1 reference

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7 January 2021

Cholesterol level, statin use and Alzheimer's disease in adults with Down syndrome

1 reference

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7 January 2021

Total serum cholesterol levels and Alzheimer's dementia in patients with Down syndrome

1 reference

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7 January 2021

Adipocytokines in Down's syndrome, an atheroma-free model: Role of adiponectin

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7 January 2021

Prevalence of hypertension in adults with intellectual disability in the Netherlands

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7 January 2021

Differences in cardiovascular disease risk between nondiabetic adults with mental retardation with and without Down syndrome

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7 January 2021

Paraoxonase-1 expression is up-regulated in Down syndrome fetal liver.

1 reference

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7 January 2021

Alternating hemiplegia of childhood

1 reference

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7 January 2021

Moyamoya syndrome associated with Down syndrome: outcome after surgical revascularization

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7 January 2021

10.1016/S1474-4422(10)70112-5

Identifiers

DOI

1 reference

22 August 2017

1 reference