(Q37660895)

English

Regulation of cell signalling by uPAR.

scientific article published on January 2010

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1 reference

Europe PubMed Central

Regulation of cell signalling by uPAR. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

author name string

Harvey W Smith

1

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Chris J Marshall

2

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

publication date

1 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Nature Reviews Molecular Cell Biology

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

23-36

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Serpins and other covalent protease inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Inhibition of FAK signaling activated by urokinase receptor induces dormancy in human carcinoma cells in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase Receptor Is Associated with the Components of the JAK1/STAT1 Signaling Pathway and Leads to Activation of This Pathway upon Receptor Clustering in the Human Kidney Epithelial Tumor Cell Line TCL-598

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

An autocrine role for urokinase in phorbol ester-mediated differentiation of myeloid cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

uPAR-induced cell adhesion and migration: vitronectin provides the key

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of integrin function by the urokinase receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

CD87 (urokinase-type plasminogen activator receptor), function and pathology in hematological disorders: a review

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Intact and cleaved uPAR forms: diagnostic and prognostic value in cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase plasminogen activator receptor choreographs multiple ligand interactions: implications for tumor progression and therapy

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Evolving role of uPA/uPAR system in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Plasminogen activation and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The plasminogen activation system in inflammation.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Structure and function of the plasminogen/plasmin system

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase and its receptors in chronic kidney disease.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

uPAR: a versatile signalling orchestrator

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Structure and ligand interactions of the urokinase receptor (uPAR).

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Structure of human urokinase plasminogen activator in complex with its receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase regulates vitronectin binding by controlling urokinase receptor oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Dimerization controls the lipid raft partitioning of uPAR/CD87 and regulates its biological functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Monomer dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Characterization of low-glycosylated forms of soluble human urokinase receptor expressed in Drosophila Schneider 2 cells after deletion of glycosylation-sites.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Cellular glycosylphosphatidylinositol-specific phospholipase D regulates urokinase receptor shedding and cell surface expression

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Modification of kidney barrier function by the urokinase receptor.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Cell-surface acceleration of urokinase-catalyzed receptor cleavage

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The cleavage of the urokinase receptor regulates its multiple functions

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Mannose 6-phosphate/insulin-like growth factor 2 receptor limits cell invasion by controlling alphaVbeta3 integrin expression and proteolytic processing of urokinase-type plasminogen activator receptor.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Vascular endothelial growth factor receptor-2-induced initial endothelial cell migration depends on the presence of the urokinase receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase induces basophil chemotaxis through a urokinase receptor epitope that is an endogenous ligand for formyl peptide receptor-like 1 and -like 2.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

An uncleavable uPAR mutant allows dissection of signaling pathways in uPA-dependent cell migration.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activity

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Recycling of the urokinase receptor upon internalization of the uPA:serpin complexes

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

A urokinase receptor-associated protein with specific collagen binding properties

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The C-type lectin receptor Endo180 displays internalization and recycling properties distinct from other members of the mannose receptor family

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of Rac1 activation by the low density lipoprotein receptor-related protein

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Plasminogen activator inhibitor-1 regulates cell adhesion by binding to the somatomedin B domain of vitronectin

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Localization and significance of urokinase plasminogen activator and its receptor in placental tissue from intrauterine, ectopic and molar pregnancies.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase plasminogen activator (uPA) and its receptor (uPAR) in gestational tissues; Measurements and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The receptor for urokinase-type plasminogen activator is expressed by keratinocytes at the leading edge during re-epithelialization of mouse skin wounds

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Lesion-associated accumulation of uPAR/CD87- expressing infiltrating granulocytes, activated microglial cells/macrophages and upregulation by endothelial cells following TBI and FCI in humans

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor (CD87) regulates leukocyte recruitment via beta 2 integrins in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Antigen-driven lymphocyte recruitment to the lung is diminished in the absence of urokinase-type plasminogen activator (uPA) receptor, but is independent of uPA.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The absence of uPAR is associated with the progression of dermal fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor modulates cellular and angiogenic responses in obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Immunohistochemical expression of uPA, uPAR, and PAI-1 in breast carcinoma. Fibroblastic expression has strong associations with tumor pathology

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Immunohistochemical detection of the receptor for urokinase plasminogen activator in human colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Soluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Recombinant soluble urokinase receptor as a scavenger for urokinase-type plasminogen activator (uPA). Inhibition of proliferation and invasion of human ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Reduction of breast carcinoma tumor growth and lung colonization by overexpression of the soluble urokinase-type plasminogen activator receptor (CD87).

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Identification of SLURP-1 as an epidermal neuromodulator explains the clinical phenotype of Mal de Meleda

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Methylation of expanded CCG triplet repeat DNA from fragile X syndrome patients enhances nucleosome exclusion

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Identification of a novel nuclear factor-kappaB sequence involved in expression of urokinase-type plasminogen activator receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Identification of Tcf-4 as a transcriptional target of p53 signalling

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Combination Analysis of Activator Protein-1 Family Members, Sp1 and an Activator Protein-2 -Related Factor Binding to Different Regions of the Urokinase Receptor Gene in Resected Colorectal Cancers

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Analysis of specific transcriptional regulators as early predictors of independent prognostic relevance in resected colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Modulation of the receptor for urokinase-type plasminogen activator in macrophage-like U937 cells by inflammatory mediators

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of urokinase receptor mRNA stability by hnRNP C in lung epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of urokinase receptor expression by p53: novel role in stabilization of uPAR mRNA.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

p53 in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of urokinase receptor proteolytic function by the tetraspanin CD82.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Distribution and lateral mobility of the urokinase-receptor complex at the cell surface.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase plasminogen activator receptor, beta 2-integrins, and Src-kinases within a single receptor complex of human monocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Regulation of urokinase receptor function and pericellular proteolysis by the integrin alpha(5)beta(1).

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Signaling through urokinase and urokinase receptor in lung cancer cells requires interactions with beta1 integrins

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Function of the lectin domain of Mac-1/complement receptor type 3 (CD11b/CD18) in regulating neutrophil adhesion

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The urokinase receptor is required for human monocyte chemotaxis in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Function of the urokinase receptor (CD87) in neutrophil Chemotaxis

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Cancer-related inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The Receptor for Urokinase-type Plasminogen Activator Regulates Fibronectin Matrix Assembly in Human Skin Fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

The role of integrin binding sites in fibronectin matrix assembly in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-type plasminogen activator receptor regulates a novel pathway of fibronectin matrix assembly requiring Src-dependent transactivation of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Functional relevance of urinary-type plasminogen activator receptor-alpha3beta1 integrin association in proteinase regulatory pathways

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptors are required for alpha 5 beta 1 integrin-mediated signaling in tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase receptor primes cells to proliferate in response to epidermal growth factor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Cetuximab attenuates metastasis and u-PAR expression in non-small cell lung cancer: u-PAR and E-cadherin are novel biomarkers of cetuximab sensitivity.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

uPAR-deficient mouse keratinocytes fail to produce EGFR-dependent laminin-5, affecting migration in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Comparative distribution of fibronectin and vitronectin in human breast and colon carcinomas. An immunofluorescence study

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Protein complexes regulating Arp2/3-mediated actin assembly.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Mechanisms of cancer cell invasion

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Linking integrin conformation to function

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-type plasminogen activator receptor induces conformational changes in the integrin alphaMbeta2 headpiece and reorientation of its transmembrane domains

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Vitronectin and its receptors

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Electron crystallography of proteins in membranes

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Involvement of a mitogen-activated protein kinase signaling pathway in the regulation of urokinase promoter activity by c-Ha-ras.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Urokinase-type plasminogen activator stimulates the Ras/Extracellular signal-regulated kinase (ERK) signaling pathway and MCF-7 cell migration by a mechanism that requires focal adhesion kinase, Src, and Shc. Rapid dissociation of GRB2/Sps-Shc compl

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Reduced metastasis of transgenic mammary cancer in urokinase-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptor

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET.

1 reference

https://api.crossref.org/works/10.1038%2FNRM2821

31 March 2020

Requirement of an upstream AP-1 motif for the constitutive and phorbol ester-inducible expression of the urokinase-type plasminogen activator receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of fibroblast growth factors on expression of genes of the plasminogen activator and insulin-like growth factor systems by human breast fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metalloproteases cleave the urokinase-type plasminogen activator receptor in the D1-D2 linker region and expose epitopes not present in the intact soluble receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LY-6K gene: a novel molecular marker for human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase receptor interacts with alpha(v)beta5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular signal-regulated kinase functions in the urokinase receptor-dependent pathway by which neutralization of low density lipoprotein receptor-related protein promotes fibrosarcoma cell migration and matrigel invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the urokinase receptor as an adhesion receptor for vitronectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase receptor. An activation antigen in human T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of colon carcinoma cell invasion by hypoxia-inducible factor 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble receptor for urokinase plasminogen activator in both full-length and a cleaved form is present in high concentration in cystic fluid from ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase-type plasminogen activator system and breast cancer (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-linked glycosylation of the ligand-binding domain of the human urokinase receptor contributes to the affinity for its ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cellular binding site for the urokinase-type plasminogen activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase-type plasminogen activator receptors associate with beta1 and beta3 integrins of fibrosarcoma cells: dependence on extracellular matrix components.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electron microscopy of integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20027185

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NRM2821

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37660895&oldid=2225867153"