(Q37237194)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

0 references

0 references

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Malgorzata Borowiak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Francis P Pankowicz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Mercedes Barzi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Xavier Legras

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Leroy Hubert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Tian Mi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Milan Ravishankar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Qin Sun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Diane Yang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Pavel Sumazin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Sarah H Elsea

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Beatrice Bissig-Choisat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Karl-Dimiter Bissig

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

language of work or name

English

0 references

publication date

30 August 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

page(s)

12642

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

22 March 2020

start time

30 August 2016

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5013601/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Management of non-alcoholic fatty liver disease in 2015

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Target specificity of the CRISPR-Cas9 system.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

DNA targeting specificity of RNA-guided Cas9 nucleases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Monogenic diseases that can be cured by liver transplantation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Transplantation for inherited metabolic disorders of the liver

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

RNA-programmed genome editing in human cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

RNA-guided human genome engineering via Cas9

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Multiplex genome engineering using CRISPR/Cas systems

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Major challenges limiting liver transplantation in the United States.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Fast and accurate long-read alignment with Burrows-Wheeler transform

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Mechanism of eukaryotic homologous recombination

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Gene therapy progress and prospects: hydrodynamic gene delivery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Identification of genes that are associated with DNA repeats in prokaryotes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

9 September 2017

Tyrosinemia: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Nontransplant treatment of tyrosinemia

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Complete Rescue of Lethal Albino c Mice by Null Mutation of 4-Hydroxyphenylpyruvate Dioxygenase and Induction of Apoptosis of Hepatocytes in These Mice by in VivoRetrieval of the Tyrosine Catabolic Pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Different molecular basis for fumarylacetoacetate hydrolase deficiency in the two clinical forms of hereditary tyrosinemia (type I)

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

On the enzymic defects in hereditary tyrosinemia

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione).

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Frequency and outcomes of liver transplantation for nonalcoholic steatohepatitis in the United States

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

A gift from nature: the birth of the statins

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5013601

Diagnosis of organic acidemias by gas chromatography--mass spectrometry

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27572891

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS12642

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

27572891

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27572891%20AND%20SRC:MED&resulttype=core&format=json