(Q37283441)

19 August 2017

Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma (English)

1 reference

19 August 2017

Kimberly R Byrnes

0 references

Bogdan A Stoica

0 references

Genell D Hilton

1 reference

19 August 2017

Alan I Faden

series ordinal

1 reference

19 August 2017

9 July 2008

1 reference

Journal of Cerebral Blood Flow & Metabolism

19 August 2017

1 reference

19 August 2017

1 reference

19 August 2017

1 reference

19 August 2017

1845-1859

1 reference

describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2718694/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Attenuation of astrogliosis by suppressing of microglial proliferation with the cell cycle inhibitor olomoucine in rat spinal cord injury model

6 September 2017

1 reference

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Role of cell cycle proteins in CNS injury

6 September 2017

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Cyclin G1 overcomes radiation-induced G2 arrest and increases cell death through transcriptional activation of cyclin B1.

6 September 2017

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Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo.

6 September 2017

1 reference

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Roscovitine targets, protein kinases and pyridoxal kinase

6 September 2017

1 reference

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Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury

6 September 2017

1 reference

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Inflammation-induced GDNF improves locomotor function after spinal cord injury

6 September 2017

1 reference

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Flavopiridol: pleiotropic biological effects enhance its anti-cancer activity

6 September 2017

1 reference

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Astrocyte apoptosis: implications for neuroprotection

6 September 2017

1 reference

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Regeneration beyond the glial scar

6 September 2017

1 reference

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Cdk2 knockout mice are viable

6 September 2017

1 reference

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Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials

6 September 2017

1 reference

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The specificities of protein kinase inhibitors: an update

6 September 2017

1 reference

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Cycling at the interface between neurodevelopment and neurodegeneration

6 September 2017

1 reference

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Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat

6 September 2017

1 reference

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Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol

6 September 2017

1 reference

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The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4

6 September 2017

1 reference

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The mouse interferon-gamma transgene chronic hepatitis model (Review).

6 September 2017

1 reference

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Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

6 September 2017

1 reference

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Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

6 September 2017

1 reference

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

6 September 2017

1 reference

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Differential regulation of trophic and proinflammatory microglial effectors is dependent on severity of neuronal injury

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

p25/Cdk5-mediated retinoblastoma phosphorylation is an early event in neuronal cell death.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Mechanical injury to neuronal/glial cultures in microplates: role of NMDA receptors and pH in secondary neuronal cell death

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Cell cycle activation contributes to post-mitotic cell death and secondary damage after spinal cord injury.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Regional expression of key cell cycle proteins in brain from subjects with amnestic mild cognitive impairment

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Expression of two temporally distinct microglia-related gene clusters after spinal cord injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Role of the cell cycle in the pathobiology of central nervous system trauma

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

The p53-independent nuclear translocation of cyclin G1 in degenerating neurons by ischemic and traumatic insults

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

The pathobiology of moderate diffuse traumatic brain injury as identified using a new experimental model of injury in rats

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Roscovitine, olomoucine, purvalanol: inducers of apoptosis in maturing cerebellar granule neurons

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Cell cycle activation linked to neuronal cell death initiated by DNA damage

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Novel diketopiperazine enhances motor and cognitive recovery after traumatic brain injury in rats and shows neuroprotection in vitro and in vivo

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Activation of CPP32-Like Caspases Contributes to Neuronal Apoptosis and Neurological Dysfunction after Traumatic Brain Injury

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Structure and transcriptional regulation of the GFAP gene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Imidazo[2,1 -b]thiazolylmethylene- and indolylmethylene-2-indolinones: a new class of cyclin-dependent kinase inhibitors. Design, synthesis, and CDK1/cyclin B inhibition

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2718694

Cyclin D1 and Cdk4 protein induction in motor neurons after transient spinal cord ischemia in rabbits

20 October 2018

1 reference

12 December 2020

Galectin-3 is upregulated in microglial cells in response to ischemic brain lesions, but not to facial nerve axotomy

2 references

12 December 2020

Crossref

https://api.crossref.org/works/10.1038%2FJCBFM.2008.75

7 January 2021

inferred from DOI database lookup

Gene profiling in spinal cord injury shows role of cell cycle in neuronal death

1 reference

12 December 2020

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

12 December 2020

Identifiers

DOI

10.1038/JCBFM.2008.75

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

18612315

1 reference