(Q37247461)

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Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/β-catenin Pathway Inhibition

scientific article published on 12 September 2016

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Europe PubMed Central

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19 August 2017

Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/β-catenin Pathway Inhibition (English)

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Europe PubMed Central

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19 August 2017

multicellularity

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based on heuristic

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Giuseppe Pettinato

1

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31 May 2020

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Rajesh Ramanathan

2

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31 May 2020

Robert A Fisher

3

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31 May 2020

Martin J Mangino

4

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31 May 2020

Ning Zhang

5

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31 May 2020

Xuejun Wen

6

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31 May 2020

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12 September 2016

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19 August 2017

Scientific Reports

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31 May 2020

6

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31 May 2020

32888

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31 May 2020

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12 September 2016

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Induced pluripotent stem cells as a source of hepatocytes

1 reference

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Hepatogenic differentiation of mesenchymal stem cells induced by insulin like growth factor-I.

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6 September 2017

Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol

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Differentiation and transplantation of human induced pluripotent stem cell-derived hepatocyte-like cells

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6 September 2017

Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

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Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells

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An endothelial cell niche induces hepatic specification through dual repression of Wnt and Notch signaling

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6 September 2017

In vivo liver regeneration potential of human induced pluripotent stem cells from diverse origins.

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Evidence for altered Wnt signaling in psoriatic skin.

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6 September 2017

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

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Generation of functional human hepatic endoderm from human induced pluripotent stem cells

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Wnt/beta-catenin signaling in hepatic organogenesis

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Liver tissue engineering: The future of liver therapeutics

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In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art.

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Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

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Human hepatocytes: isolation, cryopreservation and applications in drug development

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Human hepatocyte transplantation: worldwide results

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Factors influencing stem cell differentiation into the hepatic lineage in vitro

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Differentiation of human umbilical cord mesenchymal stromal cells into low immunogenic hepatocyte-like cells.

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Efficient differentiation of functional hepatocytes from human embryonic stem cells

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Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.

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Microscale culture of human liver cells for drug development

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Directed differentiation of human embryonic stem cells into functional hepatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Direct differentiation of human embryonic stem cells to hepatocyte-like cells exhibiting functional activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Glutathione transferases in hepatocyte-like cells derived from human embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

beta-Catenin is critical for early postnatal liver growth.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Reversal of mouse hepatic failure using an implanted liver-assist device containing ES cell-derived hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Modeling mass transfer in hepatocyte spheroids via cell viability, spheroid size, and hepatocellular functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Bioreactor cultivation enhances the efficiency of human embryoid body (hEB) formation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Wnt impacts growth and differentiation in ex vivo liver development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

Generation of Hepatocyte-Like Cells from Human Embryonic Stem Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

GATA transcription factors as potentiators of gut endoderm differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5018737

20 October 2018

Hepatocyte behavior within three-dimensional porous alginate scaffolds

1 reference

https://pubmed.ncbi.nlm.nih.gov/27616299

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic differentiation of mesenchymal stem cells: in vitro strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/27616299

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repression of Wnt/beta-catenin signaling in the anterior endoderm is essential for liver and pancreas development

1 reference

https://pubmed.ncbi.nlm.nih.gov/27616299

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct differentiation of hepatic cells from human induced pluripotent stem cells using a limited number of cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/27616299

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatogenic potential of human bone marrow and umbilical cord blood mesenchymal stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27616299

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP32888

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27616299%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27616299%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27616299%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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