(Q37165497)

18 August 2017

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title

Insulin, insulin-like growth factors and incretins: neural homeostatic regulators and treatment opportunities (English)

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18 August 2017

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Joanna K Soczynska

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Roger S McIntyre

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18 August 2017

Dragana Vagic

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18 August 2017

Shari A Swartz

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18 August 2017

Hanna O Woldeyohannes

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18 August 2017

Lakshmi P Voruganti

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18 August 2017

Jakub Z Konarski

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18 August 2017

publication date

1 January 2008

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18 August 2017

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18 August 2017

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18 August 2017

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18 August 2017

page(s)

443-453

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Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium

18 August 2017

cites work

1 reference

12 December 2020

Stimulation of glucose uptake by the natural coenzyme alpha-lipoic acid/thioctic acid: participation of elements of the insulin signaling pathway

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12 December 2020

Gliogenesis and glial pathology in depression

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12 December 2020

The IGF-I signaling pathway

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12 December 2020

The source of cerebral insulin

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12 December 2020

Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging

1 reference

12 December 2020

Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner

1 reference

12 December 2020

Intranasal insulin improves memory in humans

1 reference

12 December 2020

Insulin promotes rapid delivery of N-methyl-D- aspartate receptors to the cell surface by exocytosis

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12 December 2020

Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells

1 reference

12 December 2020

Alpha-lipoic acid as a new treatment option for Alzheimer [corrected] type dementia

1 reference

12 December 2020

Glucagon-like peptide-1: a potent regulator of food intake in humans

1 reference

12 December 2020

Relation of diabetes to mild cognitive impairment

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12 December 2020

Cognitive function in diabetes mellitus

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12 December 2020

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations

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12 December 2020

Central nervous system effects of intranasally administered insulin during euglycemia in men.

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12 December 2020

A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in human immunodeficiency virus-associated cognitive impairment. Dana Consortium on the Therapy of HIV Dementia and Related Cognitive Disorders

1 reference

12 December 2020

Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention

1 reference

12 December 2020

Insulin receptors and signal transduction proteins in the hypothalamo-hypophyseal system: a review on morphological findings and functional implications

1 reference

12 December 2020

Brain morphometric abnormalities in geriatric depression: long-term neurobiological effects of illness duration

1 reference

12 December 2020

Insulin receptor in rat peripheral nerve: its localization and alternatively spliced isoforms

1 reference

12 December 2020

Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study

1 reference

12 December 2020

(r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia

1 reference

12 December 2020

Emerging roles of insulin-like growth factor-I in the adult brain.

1 reference

12 December 2020

Increasing the levels of insulin-like growth factor-I by an IGF binding protein inhibitor produces anxiolytic and antidepressant-like effects

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12 December 2020

Studies of hormone action in the hippocampal formation: possible relevance to depression and diabetes

1 reference

12 December 2020

Insulin metabolism in Alzheimer's disease differs according to apolipoprotein E genotype and gender

1 reference

12 December 2020

Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy

1 reference

12 December 2020

Reduction of Insulin Resistance in Obese and/or Diabetic Animals by 5-[4-(1-Methylcyclohexylmethoxy)benzyl]-thiazolidine-2,4-dione (ADD-3878, U-63,287, Ciglitazone), a New Antidiabetic Agent

1 reference

12 December 2020

Neuron somal size is decreased in the lateral amygdalar nucleus of subjects with bipolar disorder

1 reference

12 December 2020

Glucose treatment reduces memory deficits in young adult rats fed high-fat diets

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12 December 2020

Insulin sensitizers may prevent metabolic inflammation

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12 December 2020

Insulin and neurodegenerative disease: shared and specific mechanisms

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12 December 2020

Hippocampal volume and cognitive performance in long-standing Type 1 diabetic patients without macrovascular complications.

1 reference

12 December 2020

Glutamate modulators as novel interventions for mood disorders

1 reference

12 December 2020

Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine

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12 December 2020

Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.

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12 December 2020

Mood disorders and allostatic load

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12 December 2020

Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation

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12 December 2020

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

1 reference

12 December 2020

Functions of PI 3-kinase in development of the nervous system

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12 December 2020

Serum insulin-like growth factor I in brain function

1 reference

12 December 2020

Cognitive dysfunctions in bipolar disorder: evidence of neuropsychological disturbances.

1 reference

12 December 2020

Gene expression and association analysis of vascular endothelial growth factor in major depressive disorder

1 reference

12 December 2020

Heterogeneity of messenger RNA that encodes the rat insulin receptor is limited to the domain of exon 11. Analysis by RNA heteroduplex mapping, amplification of cDNA, and in vitro translation

1 reference

12 December 2020

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

1 reference

12 December 2020

Evidence of GLP-1-mediated neuroprotection in an animal model of pyridoxine-induced peripheral sensory neuropathy

1 reference

12 December 2020

The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice

1 reference

12 December 2020

Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis.

1 reference

12 December 2020

Peptide hormones: Review of current and emerging uses by nasal delivery

1 reference

12 December 2020

Intranasal insulin improves memory in humans: superiority of insulin aspart

1 reference

12 December 2020

Glucagon-like peptide-1: regulation of insulin secretion and therapeutic potential

1 reference

12 December 2020

Insulin-like growth factor I stimulates angiogenesis and the production of vascular endothelial growth factor.

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12 December 2020

Impairment of endothelial function in unipolar and bipolar depression

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12 December 2020

Structural differences between insulin receptors in the brain and peripheral target tissues.

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12 December 2020

Neurocognitive impairment in euthymic young adults with bipolar spectrum disorder and recurrent major depressive disorder

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12 December 2020

Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype

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12 December 2020

Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI.

1 reference

12 December 2020

The IRS-signalling system: a network of docking proteins that mediate insulin action

1 reference

12 December 2020

The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

1 reference

12 December 2020

Insulin signaling in the central nervous system: learning to survive

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12 December 2020

Cognitive deficits are associated with functional impairment in severely depressed patients.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo

1 reference

12 December 2020

Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal

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12 December 2020

Peroxisome proliferator-activated receptor gamma thiazolidinedione agonists increase glucose metabolism in astrocytes

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12 December 2020

Insulin-like growth factor-I mRNA and peptide in the human anterior pituitary

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12 December 2020

Neurocognitive impairment in drug-free patients with major depressive disorder

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12 December 2020

IGF1R signalling and its inhibition

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12 December 2020

Cognitive deficits in depression: possible implications for functional neuropathology

1 reference

12 December 2020

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

1 reference

12 December 2020

Decreased expression of insulin-like growth factor binding protein 2 in the prefrontal cortex of subjects with bipolar disorder and its regulation by lithium treatment

1 reference

12 December 2020

Therapeutic Potential of Peroxisome Proliferator-Activated Receptor Agonists for Neurological Disease

1 reference

12 December 2020

Increased hippocampal plaques and tangles in patients with Alzheimer disease with a lifetime history of major depression

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12 December 2020

Effect of alpha lipoic acid on intracerebroventricular streptozotocin model of cognitive impairment in rats

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12 December 2020

Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin

1 reference

12 December 2020

Proteomic analysis of specific brain proteins in aged SAMP8 mice treated with alpha-lipoic acid: implications for aging and age-related neurodegenerative disorders

1 reference

12 December 2020

A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q

1 reference

12 December 2020

Unravelling the activation mechanisms of protein kinase B/Akt

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12 December 2020

Is Glucagon-like peptide-1, an agent treating diabetes, a new hope for Alzheimer's disease?

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12 December 2020

Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

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12 December 2020

Lipoic acid improves survival in transgenic mouse models of Huntington's disease

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12 December 2020

Insulin resistance in skeletal muscles in patients with NIDDM.

1 reference

12 December 2020

Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells.

1 reference

12 December 2020

Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration

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12 December 2020

Hyperinsulinemia and risk of Alzheimer disease

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12 December 2020

10.2165/00023210-200822060-00001

Identifiers

DOI

1 reference

Dimensions Publication ID

18 August 2017

1014515378

0 references

1 reference