(Q36938295)

17 August 2017

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title

The role of anti-inflammatory agents in Parkinson's disease (English)

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17 August 2017

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Edith G McGeer

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17 August 2017

Patrick L McGeer

series ordinal

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17 August 2017

publication date

1 January 2007

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17 August 2017

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17 August 2017

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17 August 2017

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17 August 2017

page(s)

789-797

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Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

17 August 2017

cites work

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Crossref

https://api.crossref.org/works/10.2165%2F00023210-200721100-00001

Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum

21 January 2018

1 reference

12 December 2020

MHC class II positive microglia and lymphocytic infiltration are present in the substantia nigra and striatum in mouse model of Parkinson's disease

1 reference

12 December 2020

Molecular mechanisms of nigral neurodegeneration in Park2 and regulation of parkin protein by other proteins

1 reference

12 December 2020

Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease

1 reference

12 December 2020

Rate of cell death in parkinsonism indicates active neuropathological process

1 reference

12 December 2020

FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-alpha in glial cells.

1 reference

12 December 2020

Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications

1 reference

12 December 2020

Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia

1 reference

12 December 2020

Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease

1 reference

12 December 2020

3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity.

1 reference

12 December 2020

A synthetic derivative of the natural product rocaglaol is a potent inhibitor of cytokine-mediated signaling and shows neuroprotective activity in vitro and in animal models of Parkinson's disease and traumatic brain injury

1 reference

12 December 2020

Trisialoganglioside GT1b induces in vivo degeneration of nigral dopaminergic neurons: role of microglia

1 reference

12 December 2020

Activation of microglia by human neuromelanin is NF-kappaB dependent and involves p38 mitogen-activated protein kinase: implications for Parkinson's disease

1 reference

12 December 2020

Sparing of age-related macular degeneration in rheumatoid arthritis

1 reference

12 December 2020

Role of cytokines in inflammatory process in Parkinson's disease.

1 reference

12 December 2020

The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse

1 reference

12 December 2020

Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

1 reference

12 December 2020

Dopamine-derived dopaminochrome promotes H(2)O(2) release at mitochondrial complex I: stimulation by rotenone, control by Ca(2+), and relevance to Parkinson disease

1 reference

12 December 2020

Polymorphisms in the interleukin-1 alpha and beta genes and the risk for Parkinson's disease

1 reference

12 December 2020

Proliferation of microglial cells induced by 1-methyl-4-phenylpyridinium in mesencephalic cultures results from an astrocyte-dependent mechanism: role of granulocyte macrophage colony-stimulating factor.

1 reference

12 December 2020

Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

1 reference

12 December 2020

Inflammation in Parkinson's disease.

1 reference

12 December 2020

The many faces of macrophage activation

1 reference

12 December 2020

Interaction of polymorphisms in the genes encoding interleukin-6 and estrogen receptor beta on the susceptibility to Parkinson's disease

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease

1 reference

12 December 2020

Involvement of inducible nitric oxide synthase in inflammation-induced dopaminergic neurodegeneration

1 reference

12 December 2020

Early-onset familial parkinsonism due to POLG mutations

1 reference

12 December 2020

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

1 reference

12 December 2020

NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies

1 reference

12 December 2020

Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations

1 reference

12 December 2020

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

1 reference

12 December 2020

A possible role for humoral immunity in the pathogenesis of Parkinson's disease

1 reference

12 December 2020

Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics

1 reference

12 December 2020

Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease.

1 reference

12 December 2020

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

1 reference

12 December 2020

Reactive macrophages increase oxidative stress and alpha-synuclein nitration during death of dopaminergic neuronal cells in co-culture: relevance to Parkinson's disease

1 reference

12 December 2020

Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons.

1 reference

12 December 2020

Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease.

1 reference

12 December 2020

Complement C3c and related protein biomarkers in amyotrophic lateral sclerosis and Parkinson's disease

1 reference

12 December 2020

Chromogranin A induces a neurotoxic phenotype in brain microglial cells

1 reference

12 December 2020

Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.

1 reference

12 December 2020

Oxidative stress in Parkinson's disease

1 reference

12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

12 December 2020

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

1 reference

12 December 2020

Critical role for microglial NADPH oxidase in rotenone-induced degeneration of dopaminergic neurons.

1 reference

12 December 2020

Differential activation of astrocytes and microglia during post-natal development of dopaminergic neuronal death in the weaver mouse

1 reference

12 December 2020

The flavanoide caffeic acid phenethyl ester blocks 6-hydroxydopamine-induced neurotoxicity

1 reference

12 December 2020

Expression of chromogranin A in lesions in the central nervous system from patients with neurological diseases

1 reference

12 December 2020

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

1 reference

12 December 2020

The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reactions on dopaminergic system

1 reference

12 December 2020

Nigrostriatal dopaminergic neurodegeneration in the weaver mouse is mediated via neuroinflammation and alleviated by minocycline administration

1 reference

12 December 2020

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12 December 2020

Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline

1 reference

12 December 2020

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

12 December 2020

Investigation of genes coding for inflammatory components in Parkinson's disease

1 reference

12 December 2020

Free radicals in Parkinson's disease

1 reference

12 December 2020

Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure

1 reference

12 December 2020

Association of interleukin-1 beta polymorphisms with idiopathic Parkinson's disease

1 reference

12 December 2020

Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.

1 reference

12 December 2020

Microglial activation and dopamine terminal loss in early Parkinson's disease

1 reference

12 December 2020

Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys

1 reference

12 December 2020

GT1b ganglioside induces death of dopaminergic neurons in rat mesencephalic cultures

1 reference

12 December 2020

Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study

1 reference

12 December 2020

Control of microglial neurotoxicity by the fractalkine receptor

1 reference

12 December 2020

Role of Fcgamma receptors in nigral cell injury induced by Parkinson disease immunoglobulin injection into mouse substantia nigra

1 reference

12 December 2020

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage

1 reference

12 December 2020

Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-alpha, interleukin-1beta, and nitric oxide

1 reference

12 December 2020

Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging.

1 reference

12 December 2020

LRRK2 expression in normal and pathologic human brain and in human cell lines

1 reference

12 December 2020

Immunologic diseases, anti-inflammatory drugs, and Parkinson disease: a case-control study

1 reference

12 December 2020

Lewy bodies in Parkinson's disease are recognized by antibodies to complement proteins

1 reference

12 December 2020

Clinical and pathologic features of families with LRRK2-associated Parkinson's disease

1 reference

12 December 2020

Nonsteroidal anti-inflammatory drugs and the incidence of Parkinson disease

1 reference

12 December 2020

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

1 reference

12 December 2020

Up-regulation of inducible nitric oxide synthase in the substantia nigra by lipopolysaccharide causes microglial activation and neurodegeneration

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12 December 2020

Clinical features of Parkinson disease patients with homozygous leucine-rich repeat kinase 2 G2019S mutations.

1 reference

12 December 2020

Lack of toxicity of human neuromelanin to rat brain dopaminergic neurons

1 reference

12 December 2020

Proteomic analysis of microglial contribution to mouse strain-dependent dopaminergic neurotoxicity.

1 reference

12 December 2020

Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

1 reference

12 December 2020

Selective microglial activation in the rat rotenone model of Parkinson's disease

1 reference

12 December 2020

Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase

1 reference

12 December 2020

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

1 reference

12 December 2020

Genetics of Parkinson's disease and parkinsonism

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12 December 2020

Thrombin-activated microglia contribute to death of dopaminergic neurons in rat mesencephalic cultures: dual roles of mitogen-activated protein kinase signaling pathways

1 reference

12 December 2020

Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease

1 reference

12 December 2020

10.2165/00023210-200721100-00001

Identifiers

DOI

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Dimensions Publication ID

17 August 2017

1007366812

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