(Q36973852)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

A chemical and genetic approach to the mode of action of fumagillin (English)

1 reference

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30 December 2019

1 reference

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30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Yi Zhang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Jing Ruey Yeh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Andrew Mara

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Rong Ju

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

John F Hines

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Pasquale Cirone

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Hilary L Griesbach

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Scott A Holley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Craig M Crews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

publication date

1 September 2006

1 reference

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30 December 2019

published in

Chemistry and Biology

1 reference

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30 December 2019

volume

1 reference

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30 December 2019

issue

1 reference

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30 December 2019

page(s)

1001-1009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest

30 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Planar cell polarity signalling couples cell division and morphogenesis during neurulation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Identification of a specific inhibitor of the dishevelled PDZ domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Organising cells into tissues: new roles for cell adhesion molecules in planar cell polarity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Rho activity critically and selectively regulates endothelial cell organization during angiogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Planar polarity from flies to vertebrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Non-canonical Wnt signalling and regulation of gastrulation movements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

The promise and perils of Wnt signaling through beta-catenin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Linking colorectal cancer to Wnt signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Activation of rat frizzled-1 promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via pathways that require Galpha(q) and Galpha(o) function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Therapeutic potential of the anti-angiogenesis drug TNP-470.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Structure of human methionine aminopeptidase-2 complexed with fumagillin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Expression of G-protein subtypes in cultured cerebral endothelial cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Wnt signaling: a common theme in animal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

A member of the Frizzled protein family mediating axis induction by Wnt-5A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Xwnt-5A: a maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

A methionine aminopeptidase and putative regulator of translation initiation is required for cell growth and patterning in Drosophila

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

A small-molecule agonist of the Wnt signaling pathway

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Trimeric G protein-dependent frizzled signaling in Drosophila

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

4 September 2018

Angiogenesis and c-Jun

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Gene profiling of Frizzled-1 and Frizzled-2 signaling: expression of G-protein-coupled receptor chimeras in mouse F9 teratocarcinoma embryonal cells.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

PP2A:B56ϵ is required for Wnt/β-catenin signaling during embryonic development

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Wnt signaling, Ca2+, and cyclic GMP: visualizing Frizzled functions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

The role of Ppt/Wnt5 in regulating cell shape and movement during zebrafish gastrulation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Planar cell polarization requires Widerborst, a B' regulatory subunit of protein phosphatase 2A.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathway

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Signaling specificity by Frizzled receptors in Drosophila.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

Wnt5 is required for tail formation in the zebrafish embryo.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2583369

10.1016/J.CHEMBIOL.2006.07.010

4 September 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

16984890

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984890%20AND%20SRC:MED&resulttype=core&format=json