(Q36950900)

17 August 2017

1 reference

title

Ghrelin, obesity and diabetes (English)

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17 August 2017

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Matthias H Tschöp

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17 August 2017

Petra Wiedmer

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Rubén Nogueiras

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Fabio Broglio

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17 August 2017

David D'Alessio

series ordinal

1 reference

17 August 2017

publication date

1 October 2007

1 reference

Nature Clinical Practice Endocrinology and Metabolism

17 August 2017

published in

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17 August 2017

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17 August 2017

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17 August 2017

page(s)

705-712

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Growth hormone secretagogue (ghrelin-) receptors--a complex drug target for the regulation of body weight

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Intracerebroventricular acute and chronic administration of obestatin minimally affect food intake but not weight gain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Obestatin acts in brain to inhibit thirst

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Post-prandial decrease of circulating human ghrelin levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Ghrelin is an orexigenic and metabolic signaling peptide in the arcuate and paraventricular nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Ghrelin and GHS on cardiovascular applications/functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

Gut-brain axis: regulation of glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin controls hippocampal spine synapse density and memory performance

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Abdominal obesity and metabolic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Structural divergence of human ghrelin. Identification of multiple ghrelin-derived molecules produced by post-translational processing

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ingested medium-chain fatty acids are directly utilized for the acyl modification of ghrelin

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Cell biology of the ghrelin receptor

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

High constitutive signaling of the ghrelin receptor--identification of a potent inverse agonist

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Obestatin inhibits feeding but does not modulate GH and corticosterone secretion in the rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

GPR39 signaling is stimulated by zinc ions but not by obestatin

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Effects of obestatin on energy balance and growth hormone secretion in rodents

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Obestatin--a ghrelin-associated peptide that does not hold its promise to suppress food intake and motility

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Distribution and biological activity of obestatin in the rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Obestatin alters sleep in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Obestatin does not activate orphan G protein-coupled receptor GPR39

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ultradian Rhythmicity of Ghrelin Secretion in Relation with GH, Feeding Behavior, and Sleep-Wake Patterns in Rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin induces adiposity in rodents

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Role of the duodenum and macronutrient type in ghrelin regulation

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin: a link between eating disorders, obesity and reproduction.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Resistance to the orexigenic effect of ghrelin in dietary-induced obesity in mice: reversal upon weight loss

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Changes in 24-h area-under-the-curve ghrelin values following diet-induced weight loss are associated with loss of fat-free mass, but not with changes in fat mass, insulin levels or insulin sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Deletion of Ghrelin Impairs neither Growth nor Appetite

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

GH-releasing peptide-2 increases fat mass in mice lacking NPY: indication for a crucial mediating role of hypothalamic agouti-related protein

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Growth hormone receptor deficiency results in blunted ghrelin feeding response, obesity, and hypolipidemia in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Identification of a mouse ghrelin gene transcript that contains intron 2 and is regulated in the pituitary and hypothalamus in response to metabolic stress.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Synaptic plasticity in energy balance regulation

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Hypothalamic paraventricular injections of ghrelin: effect on feeding and c-Fos immunoreactivity.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Neural basis of orexigenic effects of ghrelin acting within lateral hypothalamus.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Hyperphagic effects of brainstem ghrelin administration

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin induces feeding in the mesolimbic reward pathway between the ventral tegmental area and the nucleus accumbens

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Expression of ghrelin receptor mRNA in the rat and the mouse brain

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Neither agouti-related protein nor neuropeptide Y is critically required for the regulation of energy homeostasis in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin action in the brain controls adipocyte metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Vaccination against weight gain

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Relationship between ghrelin and energy expenditure in healthy young women

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Centrally administered ghrelin suppresses sympathetic nerve activity in brown adipose tissue of rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin regulates mitochondrial-lipid metabolism gene expression and tissue fat distribution in liver and skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Insulin regulates plasma ghrelin concentration

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin levels correlate with insulin levels, insulin resistance, and high-density lipoprotein cholesterol, but not with gender, menopausal status, or cortisol levels in humans

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Mice lacking ghrelin receptors resist the development of diet-induced obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Dose-dependent inhibition by ghrelin of insulin secretion in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in beta-cells: implication in the glycemic control in rodents

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

IA-2beta, but not IA-2, is induced by ghrelin and inhibits glucose-stimulated insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin prevents development of diabetes at adult age in streptozotocin-treated newborn rats.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Circulating ghrelin levels are decreased in human obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin as a potential anti-obesity target

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Absence of ghrelin protects against early-onset obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Is ghrelin a signal for the development of metabolic systems?

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Genetics and pathophysiology of human obesity

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

High circulating ghrelin: a potential cause for hyperphagia and obesity in prader-willi syndrome

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin, a novel growth hormone-releasing peptide, in the treatment of cardiopulmonary-associated cachexia

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study.

1 reference

https://api.crossref.org/works/10.1038%2FNCPENDMET0625

7 January 2021

Identifiers

DOI

10.1038/NCPENDMET0625

1 reference

release_lzluk4hz6nex5mrtw4sjx745um

17 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lzluk4hz6nex5mrtw4sjx745um

24 November 2022

mapped directly with Wikidata item

1 reference