(Q36817570)

16 August 2017

Side-specific endothelial-dependent regulation of aortic valve calcification: interplay of hemodynamics and nitric oxide signaling. (English)

1 reference

16 August 2017

0 references

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Jennifer Richards

1 reference

16 August 2017

Ismail El-Hamamsy

1 reference

16 August 2017

Si Chen

1 reference

16 August 2017

Zubair Sarang

1 reference

16 August 2017

Padmini Sarathchandra

1 reference

16 August 2017

Magdi H Yacoub

1 reference

16 August 2017

Adrian H Chester

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16 August 2017

Jonathan T Butcher

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16 August 2017

language of work or name

English

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publication date

13 March 2013

1 reference

The American Journal of Pathology

16 August 2017

1 reference

16 August 2017

182

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16 August 2017

1 reference

16 August 2017

1922-1931

1 reference

describes a project that uses

16 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3644712/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Insights into the use of biomarkers in calcific aortic valve disease

29 September 2017

1 reference

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Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents.

29 September 2017

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Statin therapy and aortic stenosis: a systematic review of the effects of statin therapy on aortic stenosis

29 September 2017

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Photodegradable hydrogels for dynamic tuning of physical and chemical properties

29 September 2017

1 reference

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A measured approach to managing the aortic root in patients with bicuspid aortic valve disease

29 September 2017

1 reference

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Identification and characterization of aortic valve mesenchymal progenitor cells with robust osteogenic calcification potential

29 September 2017

1 reference

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Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice

29 September 2017

1 reference

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Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathway

29 September 2017

1 reference

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Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans.

29 September 2017

1 reference

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Design of an ex vivo culture system to investigate the effects of shear stress on cardiovascular tissue

29 September 2017

1 reference

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Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis

29 September 2017

1 reference

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Mutations in NOTCH1 cause aortic valve disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves.

29 September 2017

1 reference

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Porcine aortic valve interstitial cells in three-dimensional culture: comparison of phenotype with aortic smooth muscle cells.

29 September 2017

1 reference

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Endothelial function. From vascular biology to clinical applications

29 September 2017

1 reference

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Cellular and molecular mechanisms of endothelial cell dysfunction

29 September 2017

1 reference

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On the history and mechanism of alizarin and alizarin red S stains for calcium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Endothelial cell orientation on aortic valve leaflets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Nitric oxide: physiology, pathophysiology, and pharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Isolation of valvular endothelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Hypercholesterolemia induces side-specific phenotypic changes and peroxisome proliferator-activated receptor-gamma pathway activation in swine aortic valve endothelium

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Transforming growth factor-beta regulates in vitro heart valve repair by activated valve interstitial cells

27 June 2018

1 reference

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A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Phenotypic and functional changes in regenerated porcine coronary endothelial cells : increased uptake of modified LDL and reduced production of NO.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Micromechanics of the fibrosa and the ventricularis in aortic valve leaflets

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Endothelium-dependent regulation of the mechanical properties of aortic valve cusps

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Oxidation, inflammation, and aortic valve calcification peroxide paves an osteogenic path

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Regulation of valvular interstitial cell calcification by components of the extracellular matrix

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Activation of valvular interstitial cells is mediated by transforming growth factor-beta1 interactions with matrix molecules

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Elastic fiber production in cardiovascular tissue-equivalents

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Effects of the reactive oxygen species hydrogen peroxide and hypochlorite on endothelial nitric oxide production.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Abnormal aortic valve development in mice lacking endothelial nitric oxide synthase

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644712

Stress sharing between the sinus and leaflets of canine aortic valve

5 September 2018

1 reference

12 December 2020

Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies

1 reference

12 December 2020

Association of Aortic-Valve Sclerosis with Cardiovascular Mortality and Morbidity in the Elderly

1 reference

12 December 2020

On the biaxial mechanical properties of the layers of the aortic valve leaflet

1 reference

12 December 2020

Early calcifications in human coronary arteries as determined with a proton microprobe

1 reference

12 December 2020

Inhibition of Pathological Differentiation of Valvular Interstitial Cells by C-Type Natriuretic Peptide

1 reference

12 December 2020

Bone formation and inflammation in cardiac valves

1 reference

12 December 2020

Aortic valve sclerosis is associatedwith systemic endothelial dysfunction

1 reference

12 December 2020

10.1016/J.AJPATH.2013.01.037

Identifiers

DOI

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

23499458

1 reference