(Q36773354)

16 August 2017

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title

PARP inhibitors and heart failure--translational medicine caught in the act. (English)

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16 August 2017

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George W Booz

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16 August 2017

publication date

1 March 2007

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16 August 2017

published in

Congestive Heart Failure

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16 August 2017

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16 August 2017

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16 August 2017

page(s)

105-112

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Nitrosative stress and pharmacological modulation of heart failure

16 August 2017

cites work

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Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

21 January 2018

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Cardioprotective effects of poly(ADP-ribose) polymerase inhibition

21 January 2018

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Poly(ADP-ribose): novel functions for an old molecule

21 January 2018

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Novel modulators of poly(ADP-ribose) polymerase

21 January 2018

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21 January 2018

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AMP-activated protein kinase is a positive regulator of poly(ADP-ribose) polymerase

21 January 2018

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Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription

21 January 2018

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Nitric oxide-dependent negative feedback of PARP-1 trans-activation of the inducible nitric-oxide synthase gene

21 January 2018

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Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations

21 January 2018

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

21 January 2018

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A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription.

21 January 2018

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Alkylating DNA damage stimulates a regulated form of necrotic cell death

21 January 2018

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Critical role of PI3-kinase/Akt activation in the PARP inhibitor induced heart function recovery during ischemia-reperfusion

21 January 2018

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PARP inhibition prevents postinfarction myocardial remodeling and heart failure via the protein kinase C/glycogen synthase kinase-3beta pathway

21 January 2018

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Glycogen synthase kinase 3beta together with 14-3-3 protein regulates diabetic cardiomyopathy: effect of losartan and tempol

21 January 2018

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Differential regulation of activator protein-1 and heat shock factor-1 in myocardial ischemia and reperfusion injury: role of poly(ADP-ribose) polymerase-1.

21 January 2018

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Apoptosis effector mechanisms: a requiem performed in different keys

21 January 2018

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Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

21 January 2018

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Poly(ADP-ribose) polymerase-1 hyperactivation and impairment of mitochondrial respiratory chain complex I function in reperfused mouse hearts

21 January 2018

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Apoptosis-inducing factor: vital and lethal

21 January 2018

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Poly(ADP-ribose) (PAR) polymer is a death signal

21 January 2018

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Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation

21 January 2018

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Players in the PARP-1 cell-death pathway: JNK1 joins the cast.

21 January 2018

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NAD+ metabolism in health and disease

21 January 2018

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

21 January 2018

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Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked?

21 January 2018

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Therapeutic potential of resveratrol: the in vivo evidence

21 January 2018

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Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

21 January 2018

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Inhibition of poly(ADP-ribose) polymerase in cancer

21 January 2018

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Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone

21 January 2018

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Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling

21 January 2018

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Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors

21 January 2018

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Poly(ADP-ribose)polymerase inhibition - where now?

21 January 2018

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Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis

21 January 2018

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Poly(ADP-ribose)polymerase inhibition decreases angiogenesis

21 January 2018

1 reference

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Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its partner tankyrase

21 January 2018

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Potential role of poly(adenosine 5'-diphosphate-ribose) polymerase activation in the pathogenesis of myocardial contractile dysfunction associated with human septic shock

21 January 2018

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Poly (ADP) ribose polymerase inhibition improves rat cardiac allograft survival

21 January 2018

1 reference

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Poly(ADP-ribose) polymerase contributes to the development of myocardial infarction in diabetic rats and regulates the nuclear translocation of apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-5299.2007.06595.X

Inhibition of poly(adp-ribose) polymerase reduces cardiomyocytic apoptosis after global cardiac arrest under cardiopulmonary bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-5299.2007.06595.X

Poly(ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-5299.2007.06595.X

10.1111/J.1527-5299.2007.06595.X

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference