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Stress and mTORture signaling

scientific article published on October 2006

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Europe PubMed Central

PubMed publication ID

15 August 2017

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Europe PubMed Central

Stress and mTORture signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

author name string

Reiling JH

1

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Europe PubMed Central

PubMed publication ID

15 August 2017

Sabatini DM

2

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Europe PubMed Central

PubMed publication ID

15 August 2017

language of work or name

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publication date

1 October 2006

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

48

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

6373-6383

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Dietary restriction in long-lived dwarf flies.

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How are the sizes of cells, organs, and bodies controlled?

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Genetics: influence of TOR kinase on lifespan in C. elegans

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Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

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Hydrogen peroxide activates p70(S6k) signaling pathway

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ROS, stress-activated kinases and stress signaling in cancer

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling

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Signaling pathways used in trabecular matrix metalloproteinase response to mechanical stretch.

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Advances in protein kinase B signalling: AKTion on multiple fronts

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Activation of p70 ribosomal protein S6 kinase is an essential step in the DNA damage-dependent signaling pathway responsible for the ultraviolet B-mediated increase in interstitial collagenase (MMP-1) and stromelysin-1 (MMP-3) protein levels in huma

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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

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TSC2 regulates VEGF through mTOR-dependent and -independent pathways

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hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

1 reference

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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

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Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

1 reference

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7 January 2021

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A nutrient sensor mechanism controls Drosophila growth.

1 reference

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7 January 2021

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Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

1 reference

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Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53.

1 reference

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7 January 2021

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Hypertonic shock inhibits growth factor receptor signaling, induces caspase-3 activation, and causes reversible fragmentation of the mitochondrial network.

1 reference

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7 January 2021

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Hypothalamic mTOR signaling regulates food intake

1 reference

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7 January 2021

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The GATA transcription factors GLN3 and GAT1 link TOR to salt stress in Saccharomyces cerevisiae.

1 reference

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7 January 2021

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The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability

1 reference

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7 January 2021

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Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

1 reference

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7 January 2021

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Mammalian TOR: a homeostatic ATP sensor

1 reference

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7 January 2021

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Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

1 reference

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7 January 2021

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FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction

1 reference

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7 January 2021

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Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis

1 reference

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7 January 2021

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Differential role of hydrogen peroxide in UV-induced signal transduction

1 reference

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7 January 2021

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Tsc2 is not a critical target of Akt during normal Drosophila development

1 reference

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7 January 2021

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Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis

1 reference

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7 January 2021

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PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.

1 reference

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Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation

1 reference

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7 January 2021

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The coordinate regulation of the p53 and mTOR pathways in cells

1 reference

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7 January 2021

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Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoplasmic p53 polypeptide is associated with ribosomes

1 reference

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p53 is covalently linked to 5.8S rRNA.

1 reference

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based on heuristic

inferred from DOI database lookup

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

1 reference

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7 January 2021

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Interactive effects of rearing temperature and oxygen on the development of Drosophila melanogaster.

1 reference

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7 January 2021

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Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein

1 reference

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Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic pathways that regulate ageing in model organisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional genomics identifies TOR-regulated genes that control growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

An expanding role for mTOR in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The AMP-activated protein kinase pathway--new players upstream and downstream.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

AMP-activated protein kinase--development of the energy sensor concept.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The p53 pathway: positive and negative feedback loops

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of translation factors during hindlimb unloading and denervation of skeletal muscle in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

A dynamic transcriptional network communicates growth potential to ribosome synthesis and critical cell size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrogen peroxide mediates arsenite activation of p70(s6k) and extracellular signal-regulated kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Heat shock induces two distinct S6 protein kinase activities in quiescent mammalian fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular signaling during skeletal muscle atrophy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

A C. elegans mutant that lives twice as long as wild type

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of protein kinase B (Akt/RAC‐protein kinase) by cellular stress and its association with heat shock protein Hsp27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Flow-induced DNA synthesis requires signaling to a translational control pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Heat Shock Activates c-Src Tyrosine Kinases and Phosphatidylinositol 3-Kinase in NIH3T3 Fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia-induced energy stress regulates mRNA translation and cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Rheb binds and regulates the mTOR kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Autophagy in metazoans: cell survival in the land of plenty

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Arabidopsis TARGET OF RAPAMYCIN interacts with RAPTOR, which regulates the activity of S6 kinase in response to osmotic stress signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Sfp1 is a stress- and nutrient-sensitive regulator of ribosomal protein gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis of the translational apparatus is regulated at the translational level

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of the cell growth regulator mTOR by Epstein-Barr virus-encoded LMP2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenoviral proteins mimic nutrient/growth signals to activate the mTOR pathway for viral replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Osmotic stress inhibits p70/85 S6 kinase through activation of a protein phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Drosophila Rheb GTPase is required for cell cycle progression and cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin regulation of hepatic insulin-like growth factor-binding protein-1 (IGFBP-1) gene expression and mammalian target of rapamycin (mTOR) signalling is impaired by the presence of hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced oxygen at high altitude limits maximum size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia signalling in cancer and approaches to enforce tumour regression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Extension of chronological life span in yeast by decreased TOR pathway signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of mammalian translation factors by nutrients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Heat shock factors and the control of the stress response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Rheb promotes cell growth as a component of the insulin/TOR signalling network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Heat-shock-induced alterations of ribosomal protein phosphorylation in plant cell cultures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The WD repeat: a common architecture for diverse functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of PTEN transcription by p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Rheb is an essential regulator of S6K in controlling cell growth in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

4E-BP functions as a metabolic brake used under stress conditions but not during normal growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Performance of a Brazilian population sample in the Boston Diagnostic Aphasia Examination: a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Combinatorial control of the specificity of protein tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Free radicals, metals and antioxidants in oxidative stress-induced cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Heat shock increases the association of binding protein-1 with initiation factor 4E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular organization of target of rapamycin complex 2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Drosophila target of rapamycin kinase functions as a multimer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209889

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1209889

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 August 2017

ResearchGate publication ID

0 references

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