(Q36685866)

15 August 2017

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title

Slicer and the argonautes (English)

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15 August 2017

Leemor Joshua-Tor

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Niraj H Tolia

object named as

Niraj H Tolia

series ordinal

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language of work or name

1 reference

1 January 2007

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15 August 2017

published in

Nature Chemical Biology

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15 August 2017

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15 August 2017

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15 August 2017

page(s)

36-43

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An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

15 August 2017

cites work

1 reference

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A role for the P-body component GW182 in microRNA function

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

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Argonaute2, a link between genetic and biochemical analyses of RNAi

21 January 2018

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A micrococcal nuclease homologue in RNAi effector complexes

21 January 2018

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21 January 2018

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A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

21 January 2018

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Crystal structure of Argonaute and its implications for RISC slicer activity

21 January 2018

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Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

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Crystal structure of a PIWI protein suggests mechanisms for siRNA recognition and slicer activity

21 January 2018

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

21 January 2018

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Ribonucleases H of retroviral and cellular origin

21 January 2018

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RISC is a 5' phosphomonoester-producing RNA endonuclease

21 January 2018

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The RNA-induced silencing complex is a Mg2+-dependent endonuclease.

21 January 2018

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

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ATP requirements and small interfering RNA structure in the RNA interference pathway

21 January 2018

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Purified Argonaute2 and an siRNA form recombinant human RISC

21 January 2018

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Biochemical identification of Argonaute 2 as the sole protein required for RNA-induced silencing complex activity

21 January 2018

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Argonaute and RNA--getting into the groove

21 January 2018

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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

21 January 2018

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Structure and nucleic-acid binding of the Drosophila Argonaute 2 PAZ domain

21 January 2018

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Structure and conserved RNA binding of the PAZ domain

21 January 2018

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Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain

21 January 2018

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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

21 January 2018

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Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

21 January 2018

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Stereochemical course of Escherichia coli RNase H.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO848

A general two-metal-ion mechanism for catalytic RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Two-metal active site binding of a Tn5 transposase synaptic complex

21 January 2018

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Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs

21 January 2018

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Biochemical specialization within Arabidopsis RNA silencing pathways

21 January 2018

1 reference

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Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Slicer function of Drosophila Argonautes and its involvement in RISC formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Argonaute slicing is required for heterochromatic silencing and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

The rde-1 gene, RNA interference, and transposon silencing in C. elegans

21 January 2018

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The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Sequence-independent assembly of spermatid mRNAs into messenger ribonucleoprotein particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Two mouse piwi-related genes: miwi and mili

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

A novel class of small RNAs in mouse spermatogenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Characterization of the piRNA Complex from Rat Testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

PPW-1, a PAZ/PIWI protein required for efficient germline RNAi, is defective in a natural isolate of C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

A genome-wide screen identifies 27 genes involved in transposon silencing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Specificity of microRNA target selection in translational repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Prediction of mammalian microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Identification of Drosophila MicroRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Structure and function of argonaute proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

21 January 2018

RNAi: RISC gets loaded.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Cleavage of the siRNA passenger strand during RISC assembly in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

In vitro analysis of RNA interference in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Ubiquitin ligase component Cul4 associates with Clr4 histone methyltransferase to assemble heterochromatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Two novel proteins, dos1 and dos2, interact with rik1 to regulate heterochromatic RNA interference and histone modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

The Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

MicroRNAs and other tiny endogenous RNAs in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Histone H3 lysine 9 methylation is required for DNA elimination in developing macronuclei in Tetrahymena.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Analysis of a piwi-related gene implicates small RNAs in genome rearrangement in tetrahymena

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

Methylation of histone h3 at lysine 9 targets programmed DNA elimination in tetrahymena

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

RNAi and the P-body connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

Integrating DNA: transposases and retroviral integrases

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

Single active site catalysis of the successive phosphoryl transfer steps by DNA transposases: insights from phosphorothioate stereoselectivity

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

A novel class of small RNAs bind to MILI protein in mouse testes

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

A germline-specific class of small RNAs binds mammalian Piwi proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO848

7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO848

1 reference

15 August 2017

1 reference