(Q36528512)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

review article

1 reference

title

PPAR Genomics and Pharmacogenomics: Implications for Cardiovascular Disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Sharon Cresci

1 reference

14 August 2017

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

374549

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

5 January 2020

start time

1 January 2008

1 reference

April 2022 Public Data File from Crossref

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone

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The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the Data From an Epidemiological Study on the Insulin Resi

30 September 2017

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Sequence variation in PPARG may underlie differential response to troglitazone

30 September 2017

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30 September 2017

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Nuclear receptors and their relevance to diseases related to lipid metabolism

30 September 2017

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30 September 2017

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Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy

30 September 2017

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Peroxisome proliferator-activated receptor beta/delta activation inhibits hypertrophy in neonatal rat cardiomyocytes

30 September 2017

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Nuclear receptor signaling and cardiac energetics

30 September 2017

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30 September 2017

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Changes in insulin sensitivity in response to troglitazone do not differ between subjects with and without the common, functional Pro12Ala peroxisome proliferator-activated receptor-gamma2 gene variant: results from the Troglitazone in Prevention of

30 September 2017

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Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse

30 September 2017

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Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

30 September 2017

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Alanine for proline substitution in the peroxisome proliferator-activated receptor gamma-2 (PPARG2) gene and the risk of incident myocardial infarction

30 September 2017

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A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

30 September 2017

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Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

30 September 2017

1 reference

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Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT).

30 September 2017

1 reference

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Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent

30 September 2017

1 reference

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Peroxisome proliferator-activated receptors, coactivators, and downstream targets

30 September 2017

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Adipose tissue as an endocrine organ

30 September 2017

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

30 September 2017

1 reference

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Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

30 September 2017

1 reference

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Deactivation of peroxisome proliferator-activated receptor-alpha during cardiac hypertrophic growth

30 September 2017

1 reference

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The human peroxisome proliferator-activated receptor alpha gene: identification and functional characterization of two natural allelic variants.

30 September 2017

1 reference

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Characterization of the human peroxisome proliferator activated receptor delta gene and its expression.

30 September 2017

1 reference

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Molecular scanning of the human PPARa gene: association of the L162v mutation with hyperapobetalipoproteinemia.

30 September 2017

1 reference

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Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR

30 September 2017

1 reference

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Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency

30 September 2017

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PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group

30 September 2017

1 reference

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A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders

30 September 2017

1 reference

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A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

30 September 2017

1 reference

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

30 September 2017

1 reference

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30 September 2017

1 reference

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Expression of peroxisome proliferator-activated receptor alpha (PPAR alpha) in primary cultures of human vascular endothelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

The organization, promoter analysis, and expression of the human PPARgamma gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

The Lipoprotein and Coronary Atherosclerosis Study (LCAS): design, methods, and baseline data of a trial of fluvastatin in patients without severe hypercholesterolemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Final report on the aspirin component of the ongoing Physicians' Health Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Response to micronized fenofibrate treatment is associated with the peroxisome-proliferator-activated receptors alpha G/C intron7 polymorphism in subjects with type 2 diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Molecular characterisation of six alternatively spliced variants and a novel promoter in human peroxisome proliferator-activated receptor alpha

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

TRIPOD (TRoglitazone In the Prevention Of Diabetes): a randomized, placebo-controlled trial of troglitazone in women with prior gestational diabetes mellitus.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Peroxisome proliferator-activated receptor gamma: A key regulator of adipogenesis and systemic insulin sensitivity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Baseline characteristics of subjects in the Lipoprotein and Coronary Atherosclerosis Study (LCAS) with fluvastatin.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance

28 June 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Hypoxia inhibits the peroxisome proliferator-activated receptor alpha/retinoid X receptor gene regulatory pathway in cardiac myocytes: a mechanism for O2-dependent modulation of mitochondrial fatty acid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

PPARbeta/delta potentiates PPARgamma-stimulated adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Association between the PPARA L162V polymorphism and plasma lipid levels: the Framingham Offspring Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Peroxisome proliferator-activated receptor alpha polymorphisms and postprandial lipemia in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease

21 January 2018

1 reference

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Influences of the PPAR alpha-L162V polymorphism on plasma HDL(2)-cholesterol response of abdominally obese men treated with gemfibrozil

21 January 2018

1 reference

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Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT).

21 January 2018

1 reference

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Insulin resistance and cardiovascular events with low HDL cholesterol: the Veterans Affairs HDL Intervention Trial (VA-HIT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Fenofibrate effect on triglyceride and postprandial response of apolipoprotein A5 variants: the GOLDN study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

A Val227Ala polymorphism in the peroxisome proliferator activated receptor alpha (PPARalpha) gene is associated with variations in serum lipid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

The V227A polymorphism at the PPARA locus is associated with serum lipid concentrations and modulates the association between dietary polyunsaturated fatty acid intake and serum high density lipoprotein concentrations in Chinese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Peroxisome proliferator--activated receptor alpha gene regulates left ventricular growth in response to exercise and hypertension

21 January 2018

1 reference

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Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: results from the Diabetes Atherosclerosis Intervention Study (DAIS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Sibling-based association study of the PPARgamma2 Pro12Ala polymorphism and metabolic variables in Chinese and Japanese hypertension families: a SAPPHIRe study. Stanford Asian-Pacific Program in Hypertension and Insulin Resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPARgamma-2) gene is associated with greater insulin sensitivity and decreased risk of type 2 diabetes in an Iranian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

PPAR-gamma2 Pro12Ala variant is associated with greater insulin sensitivity in childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Effect of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma-2 gene on adiposity, insulin sensitivity and lipid profile in the Spanish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Association of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma with Pre-diabetic phenotypes: meta-analysis of 57 studies on nondiabetic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Peroxisome proliferator-activated receptor-gamma2 P12A polymorphism and risk of coronary heart disease in US men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

The association of Pro12Ala polymorphism in PPARgamma2 with lower carotid artery IMT in Japanese

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma2 gene on rosiglitazone response in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

The 161TT genotype in the exon 6 of the peroxisome-proliferator-activated receptor gamma gene is associated with premature acute myocardial infarction and increased lipid peroxidation in habitual heavy smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Effects of PPARalpha, gamma and delta haplotypes on plasma levels of lipids, severity and progression of coronary atherosclerosis and response to statin therapy in the lipoprotein coronary atherosclerosis study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Evidence that peroxisome proliferator-activated receptor delta influences cholesterol metabolism in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

The Diabetes Prevention Program. Design and methods for a clinical trial in the prevention of type 2 diabetes

21 January 2018

2 references

https://api.crossref.org/works/10.1155%2F2008%2F374549

21 January 2018

12 December 2020

Transactivation of peroxisome proliferator-activated receptor alpha by green tea extracts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Mutation screening of the PPARalpha gene in type 2 diabetes associated with coronary heart disease.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2288645

Expression of the Peroxisome Proliferator-activated Receptor Gene Is Stimulated by Stress and Follows a Diurnal Rhythm

21 September 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Variation in the PPARα gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

A genetic polymorphism of the peroxisome proliferator-activated receptor gamma gene influences plasma leptin levels in obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Genetic Variation in PPARG Encoding Peroxisome Proliferator-Activated Receptor γ Associated With Carotid Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2008%2F374549

Baseline characteristics of the study population in the Diabetes Atherosclerosis Intervention Study (DAIS). World Health Organization Collaborating Centre for the Study of Atherosclerosis in Diabetes

21 January 2018

1 reference

12 December 2020

Activation of a novel metabolic gene regulatory pathway by chronic stimulation of skeletal muscle

1 reference

12 December 2020

Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study

1 reference

12 December 2020

Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma C161-->T polymorphism and coronary artery disease

1 reference

12 December 2020

Regulation of adipogenesis and energy balance by PPARgamma and PGC-1

1 reference

12 December 2020

Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study

1 reference

12 December 2020

Effects of fluvastatin on coronary atherosclerosis in patients with mild to moderate cholesterol elevations (Lipoprotein and Coronary Atherosclerosis Study [LCAS])

1 reference

12 December 2020

A study to determine the response of coronary atherosclerosis to raising low high density lipoprotein cholesterol with a fibric-acid derivative in men after coronary bypass surgery. The rationale, design, and baseline characteristics of the LOCAT St

1 reference

12 December 2020

The peroxisome proliferator-activated receptor alpha Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men

1 reference

12 December 2020

Prevention of the angiographic progression of coronary and vein-graft atherosclerosis by gemfibrozil after coronary bypass surgery in men with low levels of HDL cholesterol. Lopid Coronary Angiography Trial (LOCAT) Study Group

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12 December 2020

Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease risk in the Helsinki Heart Study. Implications for treatment

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Some coronary risk factors related to the insulin resistance syndrome and treatment with gemfibrozil. Experience from the Helsinki Heart Study

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12 December 2020

Identifiers

DOI

10.1155/2008/374549

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

PubMed publication ID

18401448

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18401448%20AND%20SRC:MED&resulttype=core&format=json