(Q36573999)

English

The Ras-Specific Exchange Factors Mouse Sos1 (mSos1) and mSos2 Are Regulated Differently: mSos2 Contains Ubiquitination Signals Absent in mSos1

scientific article published on December 1, 1997

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Europe PubMed Central

PMC publication ID

15 August 2017

The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1 (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

The Ras-Specific Exchange Factors Mouse Sos1 (mSos1) and mSos2 Are Regulated Differently: mSos2 Contains Ubiquitination Signals Absent in mSos1 (English)

1 reference

10.1128/MCB.17.12.7132

https://api.crossref.org/works/10.1128/MCB.17.12.7132

24 November 2024

protein ubiquitination

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K. H. Nielsen

1

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

A. G. Papageorge

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

W. C. Vass

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

B. M. Willumsen

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

D. R. Lowy

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

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1 December 1997

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15 August 2017

December 1997

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9372945

24 November 2024

full work available at URL

https://europepmc.org/articles/pmc232570?pdf=render

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

http://mcb.asm.org/cgi/content/abstract/17/12/7132

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

https://europepmc.org/articles/PMC232570

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content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

https://europepmc.org/articles/PMC232570?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9372945

24 November 2024

https://journals.asm.org/doi/pdf/10.1128/MCB.17.12.7132

1 reference

10.1128/MCB.17.12.7132

https://api.crossref.org/works/10.1128/MCB.17.12.7132

24 November 2024

https://www.tandfonline.com/doi/pdf/10.1128/MCB.17.12.7132

1 reference

10.1128/MCB.17.12.7132

https://api.crossref.org/works/10.1128/MCB.17.12.7132

24 November 2024

Molecular and Cellular Biology

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

7132-7138

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Cell surface control of the multiubiquitination and deubiquitination of high-affinity immunoglobulin E receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Function and regulation of ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Proteins regulating Ras and its relatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Accumulation of p53 in a mutant cell line defective in the ubiquitin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

The ubiquitin-proteasome proteolytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Regulation of Ras-mediated signalling: more than one way to skin a cat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

The Cellular Content of Cdc25p, the Ras Exchange Factor in Saccharomyces cerevisiae, Is Regulated by Destabilization Through a Cyclin Destruction Box

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Differential interactions of human Sos1 and Sos2 with Grb2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Ras target proteins in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Monoclonal antibodies specific for the carboxy terminus of simian virus 40 large T antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Two dominant-acting selectable markers for gene transfer studies in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

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Degradation of nuclear oncoproteins by the ubiquitin system in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Cyclin is degraded by the ubiquitin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=232570

30 September 2017

Both cyclin A delta 60 and B delta 97 are stable and arrest cells in M-phase, but only cyclin B delta 97 turns on cyclin destruction

1 reference

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The bovine papillomavirus E5 oncogene can cooperate with ras: identification of p21 amino acids critical for transformation by c-rasH but not v-rasH.

1 reference

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Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation

1 reference

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The short-lived MAT alpha 2 transcriptional regulator is ubiquitinated in vivo

1 reference

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Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

1 reference

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

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Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24

1 reference

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Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae

1 reference

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1 reference

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Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator

1 reference

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C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1 reference

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An essential role for Rac in Ras transformation

1 reference

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1 reference

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28 June 2018

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

1 reference

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Conserved structural motifs in cyclins identified by sequence analysis

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the ubiquitin-dependent proteolytic pathway in MHC class I-restricted antigen presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9372945

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Sos (Son of sevenless) protein

2

1 reference

10.1128/MCB.17.12.7132

https://api.crossref.org/works/10.1128/MCB.17.12.7132

24 November 2024

Cancer Research

16

51

712

author name string

DeClue J. E.

publication date

1991

1 reference

10.1128/MCB.17.12.7132

https://api.crossref.org/works/10.1128/MCB.17.12.7132

24 November 2024

Identifiers

10.1128/MCB.17.12.7132

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

release_asczhx6mu5g4xdahapfk4sn74e

1 reference

https://api.fatcat.wiki/v0/release/asczhx6mu5g4xdahapfk4sn74e

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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