(Q36559701)

14 August 2017

1 reference

title

Caspase-containing complexes in the regulation of cell death and inflammation (English)

1 reference

14 August 2017

1 reference

Nele Festjens

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Peter Vandenabeele

0 references

Sigrid Cornelis

1 reference

14 August 2017

Mohamed Lamkanfi

series ordinal

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14 August 2017

publication date

1 August 2006

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14 August 2017

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14 August 2017

volume

387

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14 August 2017

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14 August 2017

page(s)

1005-1016

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2006.124

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Role of prodomain in importin-mediated nuclear localization and activation of caspase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The biochemical mechanism of caspase-2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Structure of Apaf-1 in the auto-inhibited form: a critical role for ADP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The CD95 type I/type II model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The 1.4-MDa apoptosome is a critical intermediate in apoptosome maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Defects in regulation of apoptosis in caspase-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Mechanisms of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

A unified model for apical caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Activation of caspases-8 and -10 by FLIP(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Characterization of a novel proapoptotic caspase-2- and caspase-9-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

cFLIP regulation of lymphocyte activation and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The Apaf-1 apoptosome: a large caspase-activating complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Molecular cloning of the interleukin-1 beta converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Engineering a dimeric caspase-9: a re-evaluation of the induced proximity model for caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Insights into the regulatory mechanism for caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Involvement of caspase-2 long isoform in Fas-mediated cell death of human leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

RAIDD is a new 'death' adaptor molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-2 permeabilizes the outer mitochondrial membrane and disrupts the binding of cytochrome c to anionic phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Human caspase 12 has acquired deleterious mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Natural adjuvants: endogenous activators of dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Essential roles of the Bcl-2 family of proteins in caspase-2-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

ICEBERG: a novel inhibitor of interleukin-1beta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Inhibition of death receptor signals by cellular FLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Innate immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

PIDD mediates NF-kappaB activation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

ATP-activated oligomerization as a mechanism for apoptosis regulation: fold and mechanism prediction for CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase activation is required for T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Fire and death: the pyrin domain joins the death-domain superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Humoral links between sleep and the immune system: research issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

A novel caspase-2 complex containing TRAF2 and RIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Bcl-2 rescues ceramide- and etoposide-induced mitochondrial apoptosis through blockage of caspase-2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

NLRs join TLRs as innate sensors of pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The danger model: a renewed sense of self

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Innate immune recognition: mechanisms and pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

PTEN function: how normal cells control it and tumour cells lose it

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The CD95(APO-1/Fas) DISC and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Rapid turnover of c-FLIPshort is determined by its unique C-terminal tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

A novel Apaf-1-independent putative caspase-2 activation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The Birc6 (Bruce) gene regulates p53 and the mitochondrial pathway of apoptosis and is essential for mouse embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Structure of the apoptotic protease-activating factor 1 bound to ADP

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-9 and APAF-1 form an active holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase activation: the induced-proximity model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Non-apoptotic functions of caspases in cellular proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

p53-dependent caspase-2 activation in mitochondrial release of apoptosis-inducing factor and its role in renal tubular epithelial cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Subcellular localization and CARD-dependent oligomerization of the death adaptor RAIDD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Mechanisms and genes of cellular suicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Caspase-9 can be activated without proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Direct binding of Fas-associated death domain (FADD) to the tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 is regulated by the death effector domain of FADD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Death receptor-induced cell killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

CATERPILLER: a novel gene family important in immunity, cell death, and diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

In situ trapping of activated initiator caspases reveals a role for caspase-2 in heat shock-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

The death domain superfamily: a tale of two interfaces?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Requirement for aspartate-cleaved bid in apoptosis signaling by DNA-damaging anti-cancer regimens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Nod1, a CARD protein, enhances pro-interleukin-1beta processing through the interaction with pro-caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

An essential role for c-FLIP in the efficient development of mature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Injected cytochrome c induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2006.124

21 January 2018

Identifiers

DOI

10.1515/BC.2006.124

1 reference

14 August 2017

1 reference