(Q36454338)

14 August 2017

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Investigating the genetic determinants of cardiovascular disease using candidate genes and meta-analysis of association studies (English)

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14 August 2017

main subject

cardiovascular disease

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Aroon D Hingorani

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14 August 2017

Juan P Casas

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14 August 2017

Jackie Cooper

series ordinal

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14 August 2017

George J Miller

series ordinal

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14 August 2017

Steve E Humphries

series ordinal

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14 August 2017

language of work or name

English

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publication date

1 March 2006

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14 August 2017

published in

Annals of Human Genetics

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14 August 2017

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14 August 2017

issue

Pt 2

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14 August 2017

page(s)

145-169

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Longitudinal and secular trends in lipoprotein cholesterol measurements in a general population sample. The Framingham Offspring Study

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Testing for population subdivision and association in four case-control studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Münster (PROCAM) study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Heritabilities of apolipoprotein and lipid levels in three countries

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The genetics of human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Clinical correlates and heritability of flow-mediated dilation in the community: the Framingham Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Mortality in treated heterozygous familial hypercholesterolaemia: implications for clinical management. Scientific Steering Committee on behalf of the Simon Broome Register Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The effect of apolipoprotein(a)-, apolipoprotein E-, and apolipoprotein A4- polymorphisms on quantitative lipoprotein(a) concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A comprehensive linkage analysis for myocardial infarction and its related risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

G20210A prothrombin gene polymorphism and coronary ischaemic syndromes: a phenotype-specific meta-analysis of 12 034 subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genomewide Transmission/Disequilibrium Testing—Consideration of the Genotypic Relative Risks at Disease Loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Association study designs for complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Population stratification and spurious allelic association

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

ARP1 interacts with the 5' flanking region of the coagulation factor VII gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Homocysteine and stroke: evidence on a causal link from mendelian randomisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Evidence of admixture from haplotyping in an epidemiological study of UK Caucasian males: implications for association analyses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

APO B gene polymorphisms and coronary artery disease: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Epidemiological methods for studying genes and environmental factors in complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Problems of reporting genetic associations with complex outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Apolipoprotein E and atherosclerosis: insight from animal and human studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Variation in bradykinin receptor genes increases the cardiovascular risk associated with hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Cardiovascular risk in healthy men and markers of oxidative stress in diabetic men are associated with common variation in the gene for uncoupling protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Mortality in relation to smoking: 40 years' observations on male British doctors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

R643G polymorphism in PECAM-1 influences transendothelial migration of monocytes and is associated with progression of CHD and CHD events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Peroxisome proliferator-activated receptor alpha gene variants influence progression of coronary atherosclerosis and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic and cultural inheritance of serum lipids, low and high density lipoprotein cholesterol and serum apolipoproteins A-I, A-II and B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Family history is a coronary heart disease risk factor in the Second Northwick Park Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic and environmental influences on serum lipid levels in twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A comprehensive review of genetic association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Control of confounding of genetic associations in stratified populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Interaction between smoking and the stromelysin-1 (MMP3) gene 5A/6A promoter polymorphism and risk of coronary heart disease in healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic testing for cardiovascular disease susceptibility: a useful clinical management tool or possible misinformation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Gene-environment interactions in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic associations: false or true?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Replication validity of genetic association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Revisiting the clinical validity of multiplex genetic testing in complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic variants of angiotensin II receptors and cardiovascular risk in hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Heritability and correlates of intercellular adhesion molecule-1 in the Framingham Offspring Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic epidemiological studies of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Vascular biology of atherosclerosis: overview and state of the art.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Comparing costs and benefits over a 10 year period of strategies for familial hypercholesterolaemia screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetics of essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Overestimation of genetic risks owing to small sample sizes in cardiovascular studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Tests and estimates of allelic association in complex inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Parental history is an independent risk factor for coronary artery disease: the Framingham Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The future of association studies: gene-based analysis and replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic and environmental contributions to platelet aggregation: the Framingham heart study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Limitations of the odds ratio in gauging the performance of a diagnostic, prognostic, or screening marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The Family Risk Score for coronary heart disease: associations with lipids, lipoproteins, and body habitus in a middle-aged bi-racial cohort: The ARIC study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Family history as a risk factor of coronary heart disease in patients under 60 years of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Case-control studies of association in structured or admixed populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Use of unlinked genetic markers to detect population stratification in association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genes influencing HDL metabolism: new perspectives and implications for atherosclerosis prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Detecting association in a case-control study while correcting for population stratification

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Searching for genetic determinants in the new millennium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Atherosclerosis — An Inflammatory Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Angiotensinogen gene polymorphism, plasma angiotensinogen, and risk of hypertension and ischemic heart disease: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

A New Statistical Method for Haplotype Reconstruction from Population Data

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Substitution of asparagine for aspartic acid at residue 9 (D9N) of lipoprotein lipase markedly augments risk of ischaemic heart disease in male smokers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic and environmental determinants of plasma high density lipoprotein cholesterol and apolipoprotein AI concentrations in healthy middle-aged men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

No APOEepsilon4 effect on coronary heart disease risk in a cohort with low smoking prevalence: the Whitehall II study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The significant increase in cardiovascular disease risk in APOEepsilon4 carriers is evident only in men who smoke: potential relationship between reduced antioxidant status and ApoE4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Power of association and linkage tests when the disease alleles are unobserved

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: implications for linkage-disequilibrium gene mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genetic and environmental influences on the size and number of cells in the blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The APOA4 T347S variant is associated with reduced plasma TAOS in subjects with diabetes mellitus and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Improving the prediction of complex diseases by testing for multiple disease-susceptibility genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Population-based gene discovery in the post-genomic era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Parameters for reliable results in genetic association studies in common disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Linkage disequilibrium at the cystathionine β synthase (CBS) locus and the association between genetic variation at the CBS locus and plasma levels of homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

The NHLBI Twin Study: heritability of apolipoprotein A-I, B, and low density lipoprotein subclasses and concordance for lipoprotein(a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Reply to 'Haplotype block structure of the cytochrome P450 CYP2C gene cluster on chromosome 10'

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genomic Control to the extreme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

Genome scans and candidate gene approaches in the study of common diseases and variable drug responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-1809.2005.00241.X

10.1111/J.1469-1809.2005.00241.X

21 January 2018

Identifiers

DOI

1 reference

14 August 2017

1 reference