(Q36330867)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Tomohiro Watanabe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Peter J Murray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Keiko Ozato

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Prafullakumar Tailor

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Ivan J Fuss

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Atsushi Kitani

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Warren Strober

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

English

0 references

publication date

1 February 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

31 December 2019

published in

1 reference

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31 December 2019

volume

118

1 reference

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31 December 2019

issue

1 reference

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31 December 2019

page(s)

545-559

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction

31 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Defective acute inflammation in Crohn's disease: a clinical investigation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Signalling pathways and molecular interactions of NOD1 and NOD2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Negative regulation of Toll-like-receptor signaling by IRF-4.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Toll-like receptor 9-induced type I IFN protects mice from experimental colitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Anti-interleukin-12 antibody for active Crohn's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Interleukin 7 regulates the survival and generation of memory CD4 cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Role of Nod2 in the Response of Macrophages to Toll-Like Receptor Agonists

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

The immunological and genetic basis of inflammatory bowel disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

IRAK-M is a negative regulator of Toll-like receptor signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

The immunology of mucosal models of inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Toll-like receptors: critical proteins linking innate and acquired immunity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Antibodies to interleukin 12 abrogate established experimental colitis in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Adjuvant activity of 6-O-acyl-muramyldipeptides to enhance primary cellular and humoral immune responses in guinea pigs: dose-response and local reactions observed with selected compounds

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Enhancement of certain biological activities of muramyl dipeptide derivatives after conjugation to a multi-poly(DL-alanine)--poly(L-lysine) carrier

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Priming effect of muramyl peptides for induction by lipopolysaccharide of tumor necrosis factor production in mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Active repression of IFN regulatory factor-1-mediated transactivation by IFN regulatory factor-4.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

CD4+CD25+ T cells regulate colonic localization of CD4 T cells reactive to a microbial antigen.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Dendritic cell maturation induced by muramyl dipeptide (MDP) derivatives: monoacylated MDP confers TLR2/TLR4 activation

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2176188

IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity

22 September 2018

1 reference

12 December 2020

Role of toll-like receptors in spontaneous commensal-dependent colitis

1 reference

12 December 2020

Activation of toll-like receptor 3 protects against DSS-induced acute colitis

1 reference

12 December 2020

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

1 reference

12 December 2020

Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver

1 reference

12 December 2020

Induction of Nod2 in Myelomonocytic and Intestinal Epithelial Cells via Nuclear Factor-κB Activation

1 reference

12 December 2020

A liver tolerates a portal antigen by generating CD11c+ cells, which select Fas ligand+ Th2 cells via apoptosis

1 reference

12 December 2020

Muramyl dipeptide induces acute joint inflammation in the mouse

1 reference

12 December 2020

Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice

1 reference

12 December 2020

Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in h

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI33145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

PubMed publication ID

18188453

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18188453%20AND%20SRC:MED&resulttype=core&format=json