(Q36377044)

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Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

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Europe PubMed Central

PMC publication ID

13 August 2017

Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Toxoplasma gondii

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author name string

T M Scharton-Kersten

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

G Yap

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

J Magram

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

A Sher

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

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publication date

1 April 1997

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Experimental Medicine

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Europe PubMed Central

PMC publication ID

13 August 2017

185

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1261-1273

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

The role of IL12 in toxoplasmosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Role of macrophage-derived cytokines in the induction and regulation of cell-mediated immunity to Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Listeria monocytogenes induces apoptosis of infected hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Role of nitric oxide in parasitic infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Emergence of NK1.1+ cells as effectors of IFN-gamma dependent immunity to Toxoplasma gondii in MHC class I-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Reduced replication of Toxoplasma gondii is necessary for induction of bradyzoite-specific antigens: a possible role for nitric oxide in triggering stage conversion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Interleukin-12 enhances murine survival against acute toxoplasmosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

The p47phox mouse knock-out model of chronic granulomatous disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Nitric oxide synthases: Roles, tolls, and controls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Nitric oxide produced during murine listeriosis is protective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

A Role for Activated Macrophages in Resistance to Infection with Toxoplasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

How does Toxoplasma gondii enter host cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Nonoxidative microbicidal activity in normal human alveolar and peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Treatment of toxoplasmic encephalitis in mice with recombinant gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Murine gamma interferon fails to inhibit Toxoplasma gondii growth in murine fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

A method to evaluate the capacity of monocytes and macrophages to inhibit multiplication of an intracellular pathogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Macrophage oxygen-dependent antimicrobial activity. I. Susceptibility of Toxoplasma gondii to oxygen intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Specific Labeling of IntracellularToxoplasma gondiiwith Uracil*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

30 September 2017

Contribution of nitric oxide to the host parasite equilibrium in toxoplasmosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Altered immune responses in mice lacking inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Killing of Listeria monocytogenes by inflammatory neutrophils and mononuclear phagocytes from immune and nonimmune mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

Activity of Human Blood Leukocytes against Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

28 June 2018

IL-4 is protective against development of toxoplasmic encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

21 September 2018

Production of nitric oxide (NO) is not essential for protection against acute Toxoplasma gondii infection in IRF-1-/- mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

21 September 2018

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

21 September 2018

Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

21 September 2018

Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196248

21 September 2018

Strong cytolytic activity of natural killer cells is neither necessary nor sufficient for preimmune resistance to Toxoplasma gondii infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histological and Ultrastructural Studies of the Interaction of Toxoplasma gondii Tachyzoites with Mouse Omentum in Experimental Infection1

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of murine interferon gamma on murine toxoplasmosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mononuclear phagocyte antiprotozoal mechanisms: oxygen-dependent vs oxygen-independent activity against intracellular Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage oxidative metabolism and intracellular Toxoplasma gondii

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha synergizes with IFN-gamma in mediating killing of Leishmania major through the induction of nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human endothelial cells are activated by IFN-gamma to inhibit Toxoplasma gondii replication. Inhibition is due to a different mechanism from that existing in mouse macrophages and human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated microglia inhibit multiplication of Toxoplasma gondii via a nitric oxide mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon gamma modulates the expression of neutrophil-derived chemokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/9104813

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.185.7.1261

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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