(Q36226774)

12 August 2017

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title

In vivo application of RNA interference: from functional genomics to therapeutics (English)

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12 August 2017

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Patrick Y Lu

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12 August 2017

Frank Xie

series ordinal

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12 August 2017

Martin C Woodle

series ordinal

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12 August 2017

publication date

1 January 2005

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12 August 2017

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12 August 2017

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12 August 2017

page(s)

117-142

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RNAi-induced gene silencing by local electroporation in targeting brain region.

12 August 2017

cites work

1 reference

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7 January 2021

RNA interference and the use of small interfering RNA to study gene function in mammalian systems

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7 January 2021

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

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7 January 2021

Genomewide view of gene silencing by small interfering RNAs

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7 January 2021

Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice

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7 January 2021

Molecular medicine for the brain: silencing of disease genes with RNA interference

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7 January 2021

Retrovirus-delivered siRNA

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7 January 2021

siRNA relieves chronic neuropathic pain

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7 January 2021

Liposomes modified with cyclic RGD peptide for tumor targeting

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7 January 2021

RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine

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7 January 2021

Potential applications of siRNA for pain therapy

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7 January 2021

Inhibition of influenza virus production in virus-infected mice by RNA interference

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Small interfering RNA Inhibits Hepatitis B virus replication in mice

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7 January 2021

A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs

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7 January 2021

Lack of interferon response in animals to naked siRNAs

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7 January 2021

Tumor regression by targeted gene delivery to the neovasculature

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7 January 2021

Expression profiling reveals off-target gene regulation by RNAi

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7 January 2021

Block copolymer-coated calcium phosphate nanoparticles sensing intracellular environment for oligodeoxynucleotide and siRNA delivery

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7 January 2021

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

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7 January 2021

Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: in vitro and in vivo studies.

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Vector-Based in Vivo RNA Interference: Dose- and Time-Dependent Suppression of Transgene Expression

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7 January 2021

In vivo activity of nuclease-resistant siRNAs

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

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7 January 2021

Modulation of angiogenesis with siRNA inhibitors for novel therapeutics

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7 January 2021

Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

RNA interference in adult mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes

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7 January 2021

Intravenous, non-viral RNAi gene therapy of brain cancer

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Synthesis of galactosyl compounds for targeted gene delivery

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7 January 2021

Towards in vivo application of RNA interference - new toys, old problems

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7 January 2021

Pharmaceutical prospects for RNA interference.

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7 January 2021

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

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7 January 2021

Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Specificity of short interfering RNA determined through gene expression signatures

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Inhibition of hepatitis C virus protein expression by RNA interference

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Attenuation of alpha2A-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Activation of the interferon system by short-interfering RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

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7 January 2021

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

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7 January 2021

Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA.

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7 January 2021

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

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7 January 2021

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Protection against lethal influenza virus challenge by RNA interference in vivo.

1 reference

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7 January 2021

Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo

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7 January 2021

Sterically stabilized polyplex: ligand-mediated activity

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https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

siRNA-mediated gene silencing in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Caspase 8 small interfering RNA prevents acute liver failure in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2805%2954006-9

7 January 2021

p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

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12 December 2020

Gene silencing in mammals by small interfering RNAs

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12 December 2020

Novel cationic cardiolipin analogue-based liposome for efficient DNA and small interfering RNA delivery in vitro and in vivo

1 reference

12 December 2020

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

1 reference

12 December 2020

SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth.

1 reference

12 December 2020

Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery.

1 reference

12 December 2020

siRNA-mediated antitumorigenesis for drug target validation and therapeutics.

1 reference

12 December 2020

Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels

1 reference

12 December 2020

10.1016/S0065-2660(05)54006-9

Identifiers

DOI

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12 August 2017

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