(Q36131738)

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Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

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12 August 2017

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein (English)

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12 August 2017

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Gerd Fätkenheuer

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Gerd Fätkenheuer

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Ten Feizi

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Michel C. Nussenzweig

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Michel C Nussenzweig

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Lynn Morris

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Bruce D. Walker

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Bruce D Walker

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Pascal Poignard

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Pascal Poignard

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12 August 2017

Christian Gaebler

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Christian Gaebler

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Michael S Seaman

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Michael S Seaman

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Florian Klein

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Hugo Mouquet

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John Pietzsch

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Arlene Hurley

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Leonidas Stamatatos

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Leonidas Stamatatos

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Clara Lehmann

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D Noah Sather

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Johannes F Scheid

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Johannes F Scheid

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Zane Kraft

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Yan Liu

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publication date

23 July 2012

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12 August 2017

Journal of Experimental Medicine

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12 August 2017

209

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12 August 2017

8

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Europe PubMed Central

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12 August 2017

1469-1479

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Europe PubMed Central

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12 August 2017

Immune-correlates analysis of an HIV-1 vaccine efficacy trial

1 reference

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2 October 2017

The Antibody Response against HIV-1

1 reference

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2 October 2017

Two distinct broadly neutralizing antibody specificities of different clonal lineages in a single HIV-1-infected donor: implications for vaccine design

1 reference

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Prospects for an HIV vaccine: leading B cells down the right path

1 reference

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

1 reference

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Neoglycolipid-based oligosaccharide microarray system: preparation of NGLs and their noncovalent immobilization on nitrocellulose-coated glass slides for microarray analyses

1 reference

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Increasing the potency and breadth of an HIV antibody by using structure-based rational design

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

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Isolation of a human anti-HIV gp41 membrane proximal region neutralizing antibody by antigen-specific single B cell sorting

1 reference

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Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

1 reference

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Broad neutralization coverage of HIV by multiple highly potent antibodies

1 reference

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

1 reference

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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

1 reference

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2 October 2017

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

1 reference

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2 October 2017

Binding interactions between soluble HIV envelope glycoproteins and quaternary-structure-specific monoclonal antibodies PG9 and PG16.

1 reference

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2 October 2017

The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

1 reference

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2 October 2017

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

1 reference

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2 October 2017

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

1 reference

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2 October 2017

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals

1 reference

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2 October 2017

Human anti-HIV-neutralizing antibodies frequently target a conserved epitope essential for viral fitness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409500

2 October 2017

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

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2 October 2017

Anti-V3 monoclonal antibodies display broad neutralizing activities against multiple HIV-1 subtypes

1 reference

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2 October 2017

The role of antibodies in HIV vaccines

1 reference

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Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

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Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

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Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

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Effective, low-titer antibody protection against low-dose repeated mucosal SHIV challenge in macaques

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Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

1 reference

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Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay together with an analytical selection algorithm

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Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers

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Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

1 reference

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1 reference

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Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

1 reference

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Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infection

1 reference

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Characterization of neutralizing antibody responses elicited by clade A envelope immunogens derived from early transmitted viruses

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

1 reference

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A broadly neutralizing human monoclonal antibody against gp41 of human immunodeficiency virus type 1.

1 reference

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1 reference

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1 reference

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1 reference

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12 December 2020

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10.1084/JEM.20120423

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Europe PubMed Central

PMC publication ID

12 August 2017

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Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

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Europe PubMed Central

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12 August 2017

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