(Q36130914)

12 August 2017

Mammalian DNA is an endogenous danger signal that stimulates local synthesis and release of complement factor B. (English)

1 reference

12 August 2017

Timothy R Billiar

1 reference

12 August 2017

David J Kaczorowski

1 reference

12 August 2017

Melanie J Scott

1 reference

12 August 2017

John P Pibris

1 reference

12 August 2017

Amin Afrazi

1 reference

12 August 2017

Atsunori Nakao

1 reference

12 August 2017

Rebecca D Edmonds

1 reference

12 August 2017

Sodam Kim

1 reference

12 August 2017

Joon H Kwak

1 reference

12 August 2017

Yujian Liu

1 reference

12 August 2017

Jie Fan

1 reference

12 August 2017

language of work or name

English

0 references

publication date

18 July 2012

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

12 August 2017

851-860

1 reference

Creative Commons Attribution 4.0 International

12 August 2017

start time

20 April 2012

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

IFI16 is an innate immune sensor for intracellular DNA

1 reference

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Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

2 October 2017

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Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms

2 October 2017

1 reference

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Circulating mitochondrial DAMPs cause inflammatory responses to injury

2 October 2017

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Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury

2 October 2017

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HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

2 October 2017

1 reference

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RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

2 October 2017

1 reference

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

2 October 2017

1 reference

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Complement-mediated ischemia-reperfusion injury: lessons learned from animal and clinical studies

2 October 2017

1 reference

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Mechanisms of Toll-like receptor 4 (TLR4)-mediated inflammation after cold ischemia/reperfusion in the heart.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Complement driven by conformational changes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

The role of the complement system in ischemia-reperfusion injury

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Complement factor B gene regulation: synergistic effects of TNF-alpha and IFN-gamma in macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Characterization of IFN-gamma regulation of the complement factor B gene in macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Genomic DNA released by dying cells induces the maturation of APCs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

TNF-alpha stimulates the biosynthesis of complement C3 and factor B by human umbilical cord vein endothelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Extrahepatic complement biosynthesis: where, when and why?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Expression of complement in the brain: role in health and disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Development of functional diversity in mouse macrophages. Mutual exclusion of two phenotypic states

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Complement biosynthesis by mononuclear phagocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Interleukin 2 mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Hemorrhagic shock primes for increased expression of cytokine-induced neutrophil chemoattractant in the lung: role in pulmonary inflammation following lipopolysaccharide.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Lymphocytoid choriomeningitis virus activates plasmacytoid dendritic cells and induces a cytotoxic T-cell response via MyD88.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Absence of functional alternative complement pathway alleviates lupus cerebritis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

Complement gene expression by rabbit heart: upregulation by ischemia and reperfusion

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3409274

TNF-alpha regulation of C3 gene expression and protein biosynthesis in rat glomerular endothelial cells

23 September 2018

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Compartmental localization of complement component transcripts in the normal human kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Local extravascular pool of C3 is a determinant of postischemic acute renal failure

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Complement Deficiency Ameliorates Collagen-Induced Arthritis in Mice

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

IFN-alphabeta-mediated inflammatory responses and antiviral defense in liver is TLR9-independent but MyD88-dependent during murine cytomegalovirus infection

31 March 2020

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2012.00011

Improved technique of heart transplantation in rats

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22526919

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2119/MOLMED.2012.00011

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

22526919

1 reference