(Q36120748)

12 August 2017

1 reference

title

Neurotensin agonists as an alternative to antipsychotics (English)

1 reference

12 August 2017

Mona Boules

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12 August 2017

Paul Fredrickson

series ordinal

1 reference

12 August 2017

Elliott Richelson

series ordinal

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12 August 2017

language of work or name

English

0 references

publication date

1 April 2005

1 reference

Expert Opinion on Investigational Drugs

12 August 2017

published in

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12 August 2017

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12 August 2017

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12 August 2017

page(s)

359-369

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Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia

12 August 2017

cites work

1 reference

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21 January 2018

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21 January 2018

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The changing roles and targets for animal models of schizophrenia

21 January 2018

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Neurotensin receptor agonists and antagonists for schizophrenia

21 January 2018

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Placebo-controlled evaluation of four novel compounds for the treatment of schizophrenia and schizoaffective disorder

21 January 2018

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The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs

21 January 2018

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Neurotensin, schizophrenia, and antipsychotic drug action

21 January 2018

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Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons

21 January 2018

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Effects of neurotensin on midbrain dopamine neurons: Are they mediated by formation of a neurotensin?dopamine complex?

21 January 2018

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Neurotensin: an endogenous antipsychotic?

21 January 2018

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Neurotensin and neurotensin receptors

21 January 2018

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Neurotensin, a central nervous system peptide: apparent receptor binding in brain membranes

21 January 2018

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Neurotensin regulates intracellular calcium in ventral tegmental area astrocytes: evidence for the involvement of multiple receptors

21 January 2018

1 reference

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Rapid desensitization of agonist-induced calcium mobilization in transfected PC12 cells expressing the rat neurotensin receptor

21 January 2018

1 reference

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The rat neurotensin receptor expressed in Chinese hamster ovary cells mediates the release of inositol phosphates

21 January 2018

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Intramembrane interactions between neurotensin receptors and dopamine D2 receptors as a major mechanism for the neuroleptic-like action of neurotensin

21 January 2018

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Mechanisms of regulation of neurotensin receptors

21 January 2018

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Neurotensin analogs indications for use as potential antipsychotic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Characterization of the genomic structure, promoter region, and a tetranucleotide repeat polymorphism of the human neurotensin receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Stimulatory actions of insulin-like growth factor-I and transforming growth factor-alpha on intestinal neurotensin and peptide YY.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

An association study of the neurotensin receptor gene with schizophrenia and clozapine response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Activation and functional characterization of the mosaic receptor SorLA/LR11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Effects of neurotensin on regional brain concentrations of dopamine, serotonin and their main metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Interactions of neurotensin with brain dopamine systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

CCK and other peptides modulate hypothalamic norepinephrine release in the rat: dependence on hunger or satiety

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The neurobiology of neurotensin: focus on neurotensin-dopamine interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin receptor expression in the rat forebrain and midbrain: a combined analysis by in situ hybridization and receptor autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Differential expression of neurotensin receptor mRNA in the dopaminergic cell groups of the rat diencephalon and mesencephalon

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin receptors are located on dopamine-containing neurones in rat midbrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Correspondence between high affinity 125I-neurotensin binding sites and dopaminergic neurons in the rat substantia nigra and ventral tegmental area: a combined radioautographic and immunohistochemical light microscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Distribution of neurotensin binding sites in rat brain: a light microscopic radioautographic study using monoiodo [125I]Tyr3-neurotensin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Binding of [3H]neurotensin in human brain: properties and distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

[3H]neurotensin(8-13) binds in human brain to the same sites as does [3H]neurotensin but with higher affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Differential effect of haloperidol on release of neurotensin in extrapyramidal and limbic systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Atypical antipsychotic drugs selectively increase neurotensin efflux in dopamine terminal regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Chronic neuroleptic treatment enhances neurotensin receptor binding in human and rat substantia nigra

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Haloperidol rapidly increases the number of neurotensin mRNA-expressing neurons in neostriatum of the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

BMY 14802, a potential antipsychotic drug, increases expression of proneurotensin mRNA in the rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Coexpression of neurotensin and c-fos mRNAs in rat neostriatal neurons following acute haloperidol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The effects of acute antipsychotic drug administration on the neurotensin system of the developing rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Differential effects of antipsychotic drugs on the neurotensin concentration of discrete rat brain nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Pharmacological specificity of the increase in neurotensin concentrations after antipsychotic drug treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Comparison of neurotensin responses to MDL 100,907, a selective 5HT2A antagonist, with clozapine and haloperidol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Current topics: brain penetrating neurotensin analog

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: a search for common ground

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Effects of neurotensin on dopamine release and metabolism in the rat striatum and nucleus accumbens: cross-validation using in vivo voltammetry and microdialysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Pharmacological evidence for common mechanisms underlying the effects of neurotensin and neuroleptics on in vivo dopamine efflux in the rat nucleus accumbens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Muscarinic antagonists attenuate neurotensin-stimulated accumbens and striatal dopamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Activation of neurotensin receptors in the prefrontal cortex stimulates midbrain dopamine cell firing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin and cholecystokinin microinjected into the ventral tegmental area modulate microdialysate concentrations of dopamine and metabolites in the posterior nucleus accumbens

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin: central nervous system effects of a hypothalamic peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin affects hyperactivity but not stereotypy induced by pre and post synaptic dopaminergic stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Atypical neuroleptic-like behavioral effects of neurotensin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The effects of neuropeptides on discrete-trial conditioned avoidance responding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Pro-Dopamine Effects of Neurotensin on Sensorimotor Gating Deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The effects of intra-accumbens neurotensin on sensorimotor gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Anatomy and Mechanisms of Neurotensin‐Dopamine Interactions in the Central Nervous System

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Sensorimotor gating and schizophrenia. Human and animal model studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Startle gating deficits occur across prepulse intensities in schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin selectively antagonizes apomorphine-induced stereotyped climbing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The effects of neurotensin and [D-Tyr11]-NT on the hyperactivity induced by intra-accumbens administration of a potent dopamine receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

[3H]Neurotensin receptor densities in human postmortem brain tissue obtained from normal and schizophrenic persons. An autoradiographic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin receptor binding abnormalities in the entorhinal cortex in schizophrenia and affective disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Reduced CSF neurotensin concentration in drug-free schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

CSF neurotensin concentrations and antipsychotic treatment in schizophrenia and schizoaffective disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

A systemically administered neurotensin agonist blocks disruption of prepulse inhibition produced by a serotonin-2A agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The effects of systemic NT69L, a neurotensin agonist, on baseline and drug-disrupted prepulse inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Reversal of sensorimotor gating deficits in Brattleboro rats by acute administration of clozapine and a neurotensin agonist, but not haloperidol: a potential predictive model for novel antipsychotic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin agonists block the prepulse inhibition deficits produced by a 5-HT2A and an alpha1 agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Altering behavioral responses and dopamine transporter protein with antisense peptide nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

A novel neurotensin analog blocks cocaine- and D-amphetamine-induced hyperactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

In vitro binding and CNS effects of novel neurotensin agonists that cross the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neurotensin analog selective for hypothermia over antinociception and exhibiting atypical neuroleptic-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

JMV 449: a pseudopeptide analogue of neurotensin-(8-13) with highly potent and long-lasting hypothermic and analgesic effects in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Neuroprotective effect of the neurotensin analogue JMV-449 in a mouse model of permanent middle cerebral ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Tolerance to the hypothermic but not to the analgesic effect of [D-Trp11]neurotensin during the semichronic intracerebroventricular infusion of the peptide in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Stability of [D-Trp11]-neurotensin to rat brain peptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The neurotensin agonist PD149163 increases Fos expression in the prefrontal cortex of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Aphagia in the rat following microinjection of neurotensin into the ventral tegmental area

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

The effect of neurotensin on food consumption in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Blockade of nicotine-induced locomotor sensitization by a novel neurotensin analog in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Novel neurotensin analog blocks the initiation and expression of nicotine-induced locomotor sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Relationships between structure and duration of neurotensin's central action: emergence of long acting analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Comparative Antipsychotic Profiles of Neurotensin and a Related Systemically Active Peptide Agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Antinociceptive, hypothermic, hypotensive, and reinforcing effects of a novel neurotensin receptor agonist, NT69L, in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

Cellular distribution of neurotensin receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.14.4.359

10.1517/13543784.14.4.359

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference