(Q36188794)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

1 reference

title

Hypoxia-responsive transcription factors (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Cormac T Taylor

1 reference

12 August 2017

Eoin P Cummins

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12 August 2017

publication date

9 July 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

450

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

363-371

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

Free radical production in hypoxic pulmonary artery smooth muscle cells

30 December 2019

cites work

1 reference

12 December 2020

p53 cannot be induced by hypoxia alone but responds to the hypoxic microenvironment

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12 December 2020

The mammalian Jun proteins: redundancy and specificity.

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12 December 2020

To die or not to die: how does p53 decide?

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12 December 2020

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia

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12 December 2020

Hypoxia attenuates the p53 response to cellular damage

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12 December 2020

Role of redox-regulated transcription factors in inflammation, aging and age-related diseases

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12 December 2020

The C/EBP family of transcription factors in the liver and other organs

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12 December 2020

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

12 December 2020

Specific protein-1 is a universal regulator of UDP-glucose dehydrogenase expression: its positive involvement in transforming growth factor-beta signaling and inhibition in hypoxia

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12 December 2020

CREB binds to multiple loci on human chromosome 22.

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12 December 2020

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

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12 December 2020

Oxygen-regulated transcription factors and their role in pulmonary disease

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12 December 2020

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells

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12 December 2020

Positive and negative regulation of the erythropoietin gene

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12 December 2020

AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells

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12 December 2020

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain

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12 December 2020

Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function

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12 December 2020

Hydroxylation of HIF-1: oxygen sensing at the molecular level

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12 December 2020

The role of C/EBPbeta in mammary gland development and breast cancer

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12 December 2020

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1 reference

12 December 2020

AP-1 in mouse development and tumorigenesis

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12 December 2020

RTEF-1, a novel transcriptional stimulator of vascular endothelial growth factor in hypoxic endothelial cells

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12 December 2020

Hypoxic activation of nuclear factor-kappa B is mediated by a Ras and Raf signaling pathway and does not involve MAP kinase (ERK1 or ERK2).

1 reference

12 December 2020

Hypoxia/Hypoxemia-Induced activation of the procoagulant pathways and the pathogenesis of ischemia-associated thrombosis

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12 December 2020

Egr-1 mediates transcriptional activation of IGF-II gene in response to hypoxia

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12 December 2020

Regulating the p53 system through ubiquitination

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12 December 2020

Intracellular pathways linking hypoxia to activation of c-fos and AP-1

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12 December 2020

Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia

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12 December 2020

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

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12 December 2020

Hypoxia induces phosphorylation of the cyclic AMP response element-binding protein by a novel signaling mechanism

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12 December 2020

Pulmonary expression of early growth response-1: biphasic time course and effect of oxygen concentration

1 reference

12 December 2020

AP-1: a double-edged sword in tumorigenesis

1 reference

12 December 2020

A role for AP-1 in apoptosis: the case for and against

1 reference

12 December 2020

Redox regulation of p53 during hypoxia

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12 December 2020

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

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12 December 2020

Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1.

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12 December 2020

Expression of the hypoxia marker carbonic anhydrase IX is critically dependent on SP1 activity. Identification of a novel type of hypoxia-responsive enhancer

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12 December 2020

Hypoxia-associated induction of early growth response-1 gene expression

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12 December 2020

Oxygen Radicals as Messengers in Oxygen-Dependent Gene Expression

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12 December 2020

Sp1 increases expression of cyclooxygenase-2 in hypoxic vascular endothelium. Implications for the mechanisms of aortic aneurysm and heart failure

1 reference

12 December 2020

NADPH oxidase is an O2 sensor in airway chemoreceptors: evidence from K+ current modulation in wild-type and oxidase-deficient mice

1 reference

12 December 2020

Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia

1 reference

12 December 2020

Hypoxia activates jun-N-terminal kinase, extracellular signal-regulated protein kinase, and p38 kinase in pulmonary arteries

1 reference

12 December 2020

Role of hydrogen peroxide in hypoxia-induced erythropoietin production

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12 December 2020

Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect

1 reference

12 December 2020

Regulation of gadd153 mRNA expression by hypoxia in pulmonary artery smooth muscle cells.

1 reference

12 December 2020

Mitochondrial respiration in the low oxygen environment of the cell. Effect of ADP on oxygen kinetics

1 reference

12 December 2020

USF1 and USF2 mediate inhibition of human trophoblast differentiation and CYP19 gene expression by Mash-2 and hypoxia

1 reference

12 December 2020

c-JUN gene induction and AP-1 activity is regulated by a JNK-dependent pathway in hypoxic HepG2 cells

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12 December 2020

Hypoxia links ATR and p53 through replication arrest

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12 December 2020

Hypoxia increases AP-1 binding activity by enhancing capacitative Ca2+ entry in human pulmonary artery endothelial cells

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12 December 2020

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

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12 December 2020

Hypoxia--a key regulatory factor in tumour growth

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12 December 2020

Acute hypoxia increases alveolar macrophage tumor necrosis factor activity and alters NF-kappaB expression

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12 December 2020

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

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12 December 2020

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

12 December 2020

Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.

1 reference

12 December 2020

AP-1 in cell proliferation and survival

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12 December 2020

Transcriptional regulation by the phosphorylation-dependent factor CREB

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12 December 2020

Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

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12 December 2020

Cellular oxygen sensing by mitochondria: old questions, new insight

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12 December 2020

Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation

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12 December 2020

Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus.

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12 December 2020

Regulation of life and death by the zinc finger transcription factor Egr-1.

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12 December 2020

Dephosphorylated hypoxia-inducible factor 1alpha as a mediator of p53-dependent apoptosis during hypoxia

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12 December 2020

Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes

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12 December 2020

Inhibition of erythropoietin gene expression signaling involves the transcription factors GATA-2 and NF-kappaB.

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12 December 2020

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

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12 December 2020

Regulation of gene expression for tyrosine hydroxylase in oxygen sensitive cells by hypoxia

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12 December 2020

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

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12 December 2020

Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor alpha4 gene by an interaction between hypoxia-inducible factor-1 and Sp1.

1 reference

12 December 2020

Sp1-dependent regulation of the tissue inhibitor of metalloproteinases-1 promoter

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12 December 2020

Hypoxia prevents induction of aromatase expression in human trophoblast cells in culture: potential inhibitory role of the hypoxia-inducible transcription factor Mash-2 (mammalian achaete-scute homologous protein-2).

1 reference

12 December 2020

Endothelial exposure to hypoxia induces Egr-1 expression involving PKCalpha-mediated Ras/Raf-1/ERK1/2 pathway

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12 December 2020

Sp1-dependent regulation of the RTP801 promoter and its application to hypoxia-inducible VEGF plasmid for ischemic disease

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12 December 2020

GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter

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12 December 2020

Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways

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12 December 2020

Oxygen sensing by HIF hydroxylases

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12 December 2020

Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

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12 December 2020

Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin

1 reference

12 December 2020

Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element

1 reference

12 December 2020

Early Growth Response-1 gene mediates up-regulation of epidermal growth factor receptor expression during hypoxia

1 reference

12 December 2020

New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases

1 reference

12 December 2020

Cooperation between transcription factor AP-1 and NF-kappaB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia

1 reference

12 December 2020

Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism

1 reference

12 December 2020

Induction of interleukin (IL)-6 by hypoxia is mediated by nuclear factor (NF)-kappa B and NF-IL6 in cardiac myocytes.

1 reference

12 December 2020

Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia

1 reference

12 December 2020

Cellular response to hypoxia involves signaling via Smad proteins

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12 December 2020

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

1 reference

12 December 2020

Molecular regulation of the endothelin-1 gene by hypoxia. Contributions of hypoxia-inducible factor-1, activator protein-1, GATA-2, AND p300/CBP.

1 reference

12 December 2020

Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells

1 reference

12 December 2020

Up-regulation of hypoxia-inducible factor-1alpha is not sufficient for hypoxic/anoxic p53 induction

1 reference

12 December 2020

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

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12 December 2020

Regulation of the activity of Sp1-related transcription factors.

1 reference

12 December 2020

Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.

1 reference

12 December 2020

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

12 December 2020

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia

1 reference

12 December 2020

Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha

1 reference

12 December 2020

Hypoxia enhances metastatic efficiency by up-regulating Mdm2 in KHT cells and increasing resistance to apoptosis

1 reference

12 December 2020

Protein kinase C-beta and oxygen deprivation. A novel Egr-1-dependent pathway for fibrin deposition in hypoxemic vasculature

1 reference

12 December 2020

Role of Sp1 in insulin regulation of gene expression

1 reference

12 December 2020

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

1 reference

12 December 2020

A cross-talk between hypoxia and TGF-beta orchestrates erythropoietin gene regulation through SP1 and Smads

1 reference

12 December 2020

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

12 December 2020

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

1 reference

12 December 2020

Induction of interleukin 6 (IL-6) by hypoxia in vascular cells. Central role of the binding site for nuclear factor-IL-6.

1 reference

12 December 2020

10.1007/S00424-005-1413-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16007431%20AND%20SRC:MED&resulttype=core&format=json